Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Zhenqiang, ZHANG"'
Autor:
Yunfang Su, Ningning Liu, Pan Wang, Congcong Shang, Ruiqin Sun, Jinlian Ma, Zhonghua Li, Huifen Ma, Yiran Sun, Zijuan Zhang, Junying Song, Zhishen Xie, Jiangyan Xu, Zhenqiang Zhang
Publikováno v:
Chinese Medicine, Vol 19, Iss 1, Pp 1-22 (2024)
Abstract Background Huanshaodan (HSD) is a Chinese Herbal Compound which has a definite clinical effect on Alzheimer’s disease (AD), however, the underlying mechanism remains unclear. The aim of this study is to preliminarily reveal the mechanism o
Externí odkaz:
https://doaj.org/article/14bcac5d76734315a0c3d15ced091649
Autor:
Guoqiang Wang, Zijuan Zhang, Jiaxing Wang, Lu Kang, Guanmin Zheng, Baoguang Liu, Jiezhi Yang, Yangang Sun, Huahui Zeng, Zhenqiang Zhang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Lung adenocarcinoma (LUAD) is the most common subtypes of NSCLC. However, the therapeutic effects for LUAD are unsatisfactory at current stage, so it is important to find new molecular targets and therapeutic strategies. circRNAs can regulat
Externí odkaz:
https://doaj.org/article/2a32a3c7c229449a91c4c6dac0142e87
Autor:
Congcong Shang, Yunfang Su, Jinlian Ma, Zhonghua Li, Pan Wang, Huifen Ma, Junying Song, Zhenqiang Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Abnormal glucose metabolism in microglial is closely associated with Alzheimer’s disease (AD). Reprogramming of microglial glucose metabolism is centered on regulating the way in which microglial metabolize glucose to alter microglial function. The
Externí odkaz:
https://doaj.org/article/77f0808ec8294cc4b4bf391d9b68e411
Publikováno v:
Frontiers in Psychology, Vol 15 (2024)
PurposeThe purpose of this study is to investigate the impact of negative urgency on implicit mobile phone addiction tendency among college freshmen, and to observe whether social exclusion situations affect the relationship between negative urgency
Externí odkaz:
https://doaj.org/article/84a0255dd35f4de2a050f8b217eaa07d
Publikováno v:
Journal of Materials Research and Technology, Vol 26, Iss , Pp 4516-4525 (2023)
The effect of alternating magnetic field (AMF) on the microstructure evolution and mechanical properties during tempering of M50 bearing steel have been investigated for evaluating the application prospect of magnetic field in steels. Microstructural
Externí odkaz:
https://doaj.org/article/e2409d9c31f044bf9c11b92d36fcc297
Autor:
Zhiyang Yu, Wenpan Wang, Qiong Qiao, Yiran Sun, Zhishen Xie, Junying Song, Zhenqiang Zhang, Huifen Ma
Publikováno v:
Chinese Medicine and Natural Products, Vol 04, Iss 01, Pp e1-e7 (2024)
Alzheimer's disease (AD) is characterized by a complex pathogenesis, limited diagnostic methods, and a lack of effective therapeutic drugs in clinical settings, posing significant challenges in modern medical research. Bioinformatics offers new persp
Externí odkaz:
https://doaj.org/article/fbd1007a5fff4702bac51735514dc582
Publikováno v:
Metals, Vol 14, Iss 7, p 753 (2024)
In this work, a novel internal heat absorption technology using inorganic material rods is employed during the solidification process of steel ingots, aiming to control their solidification and improve the quality of the final product. The study inve
Externí odkaz:
https://doaj.org/article/e3589c7000cf4317bfc06a658676cb98
Autor:
Ye Yuan, Yamei Liu, Li Hao, Jinlian Ma, Simai Shao, Ziyang Yu, Ming Shi, Zhenqiang Zhang, Zijuan Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Alzheimer’s disease (AD) is an age-related neurodegenerative disease that progressively impairs cognitive function and memory. The occurrence and development of Alzheimer’s disease involves many processes. In response to the complex pathogenesis
Externí odkaz:
https://doaj.org/article/1c70a18a6ebd4e0aaf8e982e3c8dc8c6
Autor:
Man Li, Guoqiang Wang, Yinyin Yan, Mengyuan Jiang, Zhirong Wang, Zhenqiang Zhang, Xiangxiang Wu, Huahui Zeng
Publikováno v:
Drug Delivery, Vol 29, Iss 1, Pp 2751-2758 (2022)
Triptolide (TP) has its unique curative effect in the treatment of rheumatoid arthritis (RA), but its application is limited by the poor water solubility and multi-organ toxicity. We herein developed a novel nanoparticle platform composed of L-ascorb
Externí odkaz:
https://doaj.org/article/ac58615c88694ea38e22a7f1782f1efd
Autor:
Xiaohu Zeng, Xin Zhu, Qikang Tian, Xiaoke Tan, Ning Sun, Min Yan, Junwei Zhao, Xiangxiang Wu, Ruiqin Li, Zhenqiang Zhang, Huahui Zeng
Publikováno v:
Drug Delivery, Vol 29, Iss 1, Pp 89-98 (2022)
Celastrol is a promising antitumor drug candidate, but the poor water solubility and cytotoxicity limit its clinical application. Herein, we synthesized a Celastrol (Cel)-chitosan oligosaccharide (CSO) conjugate (Cel-CSO) for drug delivery. Celastrol
Externí odkaz:
https://doaj.org/article/8321f9c5178c4b63b4b4a918bd23bbfd