Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Zhennan Shi"'
Publikováno v:
Zhongguo Jianchuan Yanjiu, Vol 19, Iss 5, Pp 180-187 (2024)
ObjectiveA lightweight and efficient ship detection method based on the YOLO-FNC model is proposed for complex environments such as ports with dense traffic. MethodFirst, a FasterNeXt neural network module is designed on the basis of the FasterNet me
Externí odkaz:
https://doaj.org/article/ed02247a67f5437ea3d67c2f4cd43d83
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Dynamic changes in chromatin landscape affect CD8+ T cell phenotype and function in chronic infections and cancer. Here the authors show that targeting the histone demethylase LSD1 increases the persistence of progenitor exhausted CD8+ T cells, impro
Externí odkaz:
https://doaj.org/article/955b0af54ffd473f80b420733cf001e9
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-4 (2021)
The cyst(e)ine/glutathione (GSH)/glutathione peroxidase 4 (GPX4) axis is the most frequently targeted pathway to trigger the ferroptosis cascade and suppress tumor growth. Two recent studies present additional mechanisms underlying cystine starvation
Externí odkaz:
https://doaj.org/article/50bee55a5c3a4361aba7967bd6419551
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/71f912fcabdd4b64ab8440fc70f779a1
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/1649dfecf99b4077a4250a9fdd7e5927
Autor:
Chun Ma, Violetta Karwacki-Neisius, Haoran Tang, Wenjing Li, Zhennan Shi, Haolin Hu, Wenqi Xu, Zhentian Wang, Lingchun Kong, Ruitu Lv, Zheng Fan, Wenhao Zhou, Pengyuan Yang, Feizhen Wu, Jianbo Diao, Li Tan, Yujiang Geno Shi, Fei Lan, Yang Shi
Publikováno v:
Cell Reports, Vol 17, Iss 4, Pp 997-1007 (2016)
Nono is a component of the para-speckle, which stores and processes RNA. Mouse embryonic stem cells (mESCs) lack para-speckles, leaving the function of Nono in mESCs unclear. Here, we find that Nono functions as a chromatin regulator cooperating with
Externí odkaz:
https://doaj.org/article/7748b79881e6457c87da8bdf760bfc13
Autor:
M. Andrés Blanco, David B. Sykes, Ben Z. Stanger, Benjamin A. Garcia, Fei Lan, Liling Wan, Pamela J. Sung, Sara E. Meyer, Neil Palmisiano, Susumu Rokudai, Yiman Liu, Sixiang Yu, Joshua Rico, Yuwei Qi, Janice M. Reynaga, Salina Yuan, Zhennan Shi, Suying Liu, Ricardo Petroni, Jelena Milosevic, Jinyang Li, Fangxue Yan
Supplementary Data from KAT6A and ENL Form an Epigenetic Transcriptional Control Module to Drive Critical Leukemogenic Gene-Expression Programs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08944082e5e92778ca9637a67237bae6
https://doi.org/10.1158/2159-8290.22541249.v1
https://doi.org/10.1158/2159-8290.22541249.v1
Autor:
M. Andrés Blanco, David B. Sykes, Ben Z. Stanger, Benjamin A. Garcia, Fei Lan, Liling Wan, Pamela J. Sung, Sara E. Meyer, Neil Palmisiano, Susumu Rokudai, Yiman Liu, Sixiang Yu, Joshua Rico, Yuwei Qi, Janice M. Reynaga, Salina Yuan, Zhennan Shi, Suying Liu, Ricardo Petroni, Jelena Milosevic, Jinyang Li, Fangxue Yan
Epigenetic programs are dysregulated in acute myeloid leukemia (AML) and help enforce an oncogenic state of differentiation arrest. To identify key epigenetic regulators of AML cell fate, we performed a differentiation-focused CRISPR screen in AML ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::137da5138aa0253a5d42c0f930caaac6
https://doi.org/10.1158/2159-8290.c.6549584.v1
https://doi.org/10.1158/2159-8290.c.6549584.v1
Autor:
Sixiang Yu, Suying Liu, Pamela J Sung, Neil Palmisiano, Zhennan Shi, Yiman Liu, Joshua Rico, David B. Sykes, Yuwei Qi, Sara E. Meyer, Jinyang Li, Janice M Reynaga, Ricardo Petroni, Ben Z. Stanger, Susumu Rokudai, Benjamin A. Garcia, Fei Lan, Salina Yuan, Fangxue Yan, M Andres Blanco, Liling Wan, Jelena Milosevic
Publikováno v:
Cancer Discov
Epigenetic programs are dysregulated in acute myeloid leukemia (AML) and help enforce an oncogenic state of differentiation arrest. To identify key epigenetic regulators of AML cell fate, we performed a differentiation-focused CRISPR screen in AML ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a5367c316e209345368e925992fc13d
https://doi.org/10.1158/2159-8290.cd-20-1459
https://doi.org/10.1158/2159-8290.cd-20-1459
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications
Nature Communications
Exhausted CD8+ T cells are key targets of immune checkpoint blockade therapy and their ineffective reinvigoration limits the durable benefit in some cancer patients. Here, we demonstrate that histone demethylase LSD1 acts to enforce an epigenetic pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99cdef5cb3ee5424ae5c594515b14ef6
https://doaj.org/article/955b0af54ffd473f80b420733cf001e9
https://doaj.org/article/955b0af54ffd473f80b420733cf001e9