Zobrazeno 1 - 10
of 456
pro vyhledávání: '"Zhennan Gu"'
Publikováno v:
Life, Vol 13, Iss 7, p 1488 (2023)
Objectives: An analysis of the weight and blood glucose management associated with fecal microbiota transplantation (FMT) as well as metabolic diseases associated with FMT was conducted by the authors in order to provide clinical recommendations rega
Externí odkaz:
https://doaj.org/article/2dbdcbbfdb974a859bbd37cbb18946a3
Autor:
Hongchao Wang, Chen Zhang, Haiqin Chen, Zhennan Gu, Jianxin Zhao, Hao Zhang, Yong Q. Chen, Wei Chen
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Tetrahydrobiopterin (BH4) is well-known as a cofactor of phenylalanine hydroxylase (PAH) and nitric oxide synthase (NOS), but its exact role in lipogenesis is unclear. In this study, the GTP cyclohydrolase I (GTPCH) gene was overexpressed to investig
Externí odkaz:
https://doaj.org/article/33fc087277f94122b5b66752ccab8536
Autor:
Jingjing Li, Zhennan Gu, Yong Pan, Shunhe Wang, Haiqin Chen, Hao Zhang, Wei Chen, Yong Q. Chen
Publikováno v:
Lipids in Health and Disease, Vol 16, Iss 1, Pp 1-9 (2017)
Abstract Background α-linolenic acid (ALA) is an n-3 polyunsaturated fatty acid (PUFA) and the substrate for long-chain n-3 PUFAs. The beneficial effects of ALA on chronic diseases are still in dispute, unlike those of eicosapentaenoic acid (EPA) an
Externí odkaz:
https://doaj.org/article/bf0f539a154d424a9f8d7ec01bbad35f
Autor:
Kai Shan, Hongyan Qu, Keru Zhou, Liangfang Wang, Congmin Zhu, Haiqin Chen, Zhennan Gu, Jing Cui, Guoling Fu, Jiaqi Li, Heyan Chen, Rong Wang, Yumin Qi, Wei Chen, Yong Q. Chen
Publikováno v:
mSystems, Vol 4, Iss 5 (2019)
ABSTRACT Gut microbiota play important roles in host metabolism, especially in diabetes. However, why different diets lead to similar diabetic states despite being associated with different microbiota is not clear. Mice were fed two high-energy diets
Externí odkaz:
https://doaj.org/article/8e5d10140e4c480580c70cad64dc5d6c
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Pathogen-induced infectious diseases pose great threats to public health. Accordingly, many studies have investigated effective strategies targeting pathogenic infections. We previously reported the preventive effects of Lactobacillus plantarum ZS205
Externí odkaz:
https://doaj.org/article/201c6e36ab00452b86d959bd84de3f55
Autor:
Haisu Shi (史海粟), Haiqin Chen (陈海琴), Zhennan Gu (顾震南), Yuanda Song (宋元达), Hao Zhang (张灏), Wei Chen (陈卫), Yong Q. Chen (陈永泉)
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 12, Pp 2309-2321 (2015)
The ω6 and ω3 pathways are two major pathways in the biosynthesis of PUFAs. In both of these, delta 6 desaturase (FADS6) is a key bifunctional enzyme desaturating linoleic acid or α-linolenic acid. Microbial species have different propensity for a
Externí odkaz:
https://doaj.org/article/d8daea3bb9e94437b8ed9de9e2bd253d
Autor:
Xin Tang, Haiqin Chen, Tiantian Mei, Chengfeng Ge, Zhennan Gu, Hao Zhang, Yong Q. Chen, Wei Chen
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Omega-3 long-chain polyunsaturated fatty acids (LC-PUFAs) have important therapeutic and nutritional benefits in humans. In the biosynthesis pathways of these LC-PUFAs, omega-3 desaturase plays a critical role. In this study, we report a new omega-3
Externí odkaz:
https://doaj.org/article/a4531f9deaed46a8afa9d906264c625f
Autor:
Chengfeng Ge, Haiqin Chen, Tiantian Mei, Xin Tang, Lulu Chang, Zhennan Gu, Hao Zhang, Wei Chen, Yong Q. Chen
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 5 (2018)
In the industrial oleaginous fungus Mortierella alpina, the arachidonic acid (AA; C20:4; ω-6) fraction can reach 50% of the total fatty acids (TFAs) in vivo. However, the eicosapentaenoic acid (EPA; C20:5; ω-3) fraction is less than 3% when this fu
Externí odkaz:
https://doaj.org/article/c1db9743e22b4df49d9a1a2cce3ca4d4