Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Zhenna Xia"'
Autor:
Yan Chang, Bojun Yuan, Xin Wang, Yang Luan, Changhui Zhou, Qingli Wang, Xingchao Geng, Na Wei, Jiangbo Zhu, Mingyang Liao, Ming Zhang, Jing Ma, Zhaomin Zhong, Fanghua Huang, Jinbao Yu, Zhongchun Zhang, Fengjun An, Zhenna Xia, Ying Jiang, Yongsheng Yu, Tianbao Zhang, Dorothea K. Torous, Qing Ju, Chang Shi, Hongling Wang, Yiyi Cao, Stephen D. Dertinger, Bo Li
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 772:6-13
Although inter-laboratory validation efforts of the in-vivo micronucleus (MN) assay based on flow cytometry (FCM) have taken place in the EU and US, none have been organized in China. Therefore, an inter-laboratory study that included eight laborator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::762649141c5facc5836c13caa068d554
https://doi.org/10.1016/j.mrgentox.2014.04.027
https://doi.org/10.1016/j.mrgentox.2014.04.027
Autor:
Yilei Zhang, Robert V. Swanda, Litong Nie, Xiaoguang Liu, Chao Wang, Hyemin Lee, Guang Lei, Chao Mao, Pranavi Koppula, Weijie Cheng, Jie Zhang, Zhenna Xiao, Li Zhuang, Bingliang Fang, Junjie Chen, Shu-Bing Qian, Boyi Gan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Glutathione peroxidase 4 (GPX4) inhibits ferroptosis, but protein synthesis is inefficient and costly. Here, the authors reveal that cystine uptake promotes GPX4 synthesis by activating mTORC1 and show that cancer cells are sensitized to ferroptosis
Externí odkaz:
https://doaj.org/article/f3ac49c7fb974751a3e7aab804b7d325
Autor:
Fan Yao, Zhicheng Zhou, Jongchan Kim, Qinglei Hang, Zhenna Xiao, Baochau N. Ton, Liang Chang, Na Liu, Liyong Zeng, Wenqi Wang, Yumeng Wang, Peijing Zhang, Xiaoyu Hu, Xiaohua Su, Han Liang, Yutong Sun, Li Ma
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Regulation of Yes-associated protein (YAP) through the Hippo pathway is well established, but its Hippo-independent regulation remains to be elucidated. Here, the authors show that non-proteolytic ubiquitination presents another means of YAP regulati
Externí odkaz:
https://doaj.org/article/c6c5c3f681fa48b9a88a52e4fc86fcb8
Autor:
Peijing Zhang, Zhenna Xiao, Shouyu Wang, Mutian Zhang, Yongkun Wei, Qinglei Hang, Jongchan Kim, Fan Yao, Cristian Rodriguez-Aguayo, Baochau N. Ton, Minjung Lee, Yumeng Wang, Zhicheng Zhou, Liyong Zeng, Xiaoyu Hu, Sarah E. Lawhon, Ashley N. Siverly, Xiaohua Su, Jia Li, Xiaoping Xie, Xuhong Cheng, Liang-Chiu Liu, Hui-Wen Chang, Shu-Fen Chiang, Gabriel Lopez-Berestein, Anil K. Sood, Junjie Chen, M. James You, Shao-Cong Sun, Han Liang, Yun Huang, Xianbin Yang, Deqiang Sun, Yutong Sun, Mien-Chie Hung, Li Ma
Publikováno v:
Cell Reports, Vol 23, Iss 3, Pp 823-837 (2018)
Summary: Although EZH2 enzymatic inhibitors have shown antitumor effects in EZH2-mutated lymphoma and ARID1A-mutated ovarian cancer, many cancers do not respond because EZH2 can promote cancer independently of its histone methyltransferase activity.
Externí odkaz:
https://doaj.org/article/826b612e0a014d98a43b8f9d302c0b0f
Publikováno v:
Cell Stress, Vol 2, Iss 9, Pp 233-235 (2018)
Dysregulation of signaling pathways that control organ size, such as the AKT-mTOR and Hippo-YAP pathways, often leads to tumorigenesis and metastasis. The Hippo pathway effector YAP is a transcriptional co-activator overexpressed or activated in huma
Externí odkaz:
https://doaj.org/article/3e308f33a92f4209bd5c5060dd5f6db5