Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Zhenmei Gao"'
Autor:
Xianli Hu, Bo Hou, Zhiai Xu, Madiha Saeed, Fang Sun, Zhenmei Gao, Yi Lai, Tong Zhu, Fan Zhang, Wen Zhang, Haijun Yu
Publikováno v:
Advanced Science, Vol 7, Iss 8, Pp n/a-n/a (2020)
Abstract Immunotherapy aiming to harness the exquisite power of the immune system has emerged as a crucial part of clinical cancer management. However, only a subset of cancer patients responds to current immunotherapy because of low immunogenicity o
Externí odkaz:
https://doaj.org/article/566cd7e6db0d410384ef91d066ce9453
Publikováno v:
Journal of Medicinal Chemistry. 63:3028-3046
PI3K-Akt-mTOR signaling pathway has been validated as an effective targeting pathway for cancer therapy. However, no PI3K/mTOR dual inhibitor has been approved by the FDA yet. Therefore, it is still essential to discover a candidate with good efficac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::798c89014b2ccf1f18dae126f4ed6901
https://doi.org/10.1021/acs.jmedchem.9b01736
https://doi.org/10.1021/acs.jmedchem.9b01736
Publikováno v:
Journal of medicinal chemistry. 63(6)
PI3K-Akt-mTOR signaling pathway has been validated as an effective targeting pathway for cancer therapy. However, no PI3K/mTOR dual inhibitor has been approved by the FDA yet. Therefore, it is still essential to discover a candidate with good efficac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9819515de9031912e5e5d77ec7aa772e
https://pubmed.ncbi.nlm.nih.gov/32069401
https://pubmed.ncbi.nlm.nih.gov/32069401
Publikováno v:
Chemical Physics Letters. 741:137126
The smoothened receptor (SMO) plays a critical role in embryonic development. Vismodegib was approved by the FDA to treat metastatic basal-cell carcinoma. However, The D473H mutation can cause obvious drug resistance toward Vismodegib. In this work,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76c977e5cd7ad7252b9664dc17b7597f
https://doi.org/10.1016/j.cplett.2020.137126
https://doi.org/10.1016/j.cplett.2020.137126
Publikováno v:
Rehabilitation Medicine. 27:10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bffa698782bbfe2eb6f4a9c677f8b55a
https://doi.org/10.3724/sp.j.1329.2017.01010
https://doi.org/10.3724/sp.j.1329.2017.01010
Publikováno v:
Acta Microscopica. 2020, Vol. 29 Issue 6, p3266-3274. 9p.