Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Zhenlong Shao"'
Autor:
Yuan Liu, Cuifu Yu, Zhenlong Shao, Xiaohong Xia, Tumei Hu, Weiyao Kong, Xiaoyue He, Wenshuang Sun, Yuanfei Deng, Yuning Liao, Hongbiao Huang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-13 (2021)
Abstract Androgen receptor splice variant 7 (AR-V7), a form of ligand-independent and constitutively activating variant of androgen receptor (AR), is considered as the key driver to initiate castration-resistant prostate cancer (CRPC). Because AR-V7
Externí odkaz:
https://doaj.org/article/475b921610f947b4a4e3c36febb984eb
Autor:
Yuning Liao, Zhenlong Shao, Yuan Liu, Xiaohong Xia, Yuanfei Deng, Cuifu Yu, Wenshuang Sun, Weiyao Kong, Xiaoyue He, Fang Liu, Zhiqiang Guo, Guoxing Chen, Daolin Tang, Huoye Gan, Jinbao Liu, Hongbiao Huang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-16 (2021)
Abstract Background Hepatocellular carcinoma (HCC) remains a medical challenge due to its high proliferation and metastasis. Although deubiquitinating enzymes (DUBs) play a key role in regulating protein degradation, their pathological roles in HCC h
Externí odkaz:
https://doaj.org/article/a8687c9fed95485abac156ed27348169
Autor:
Xiaohong Xia, Chuyi Huang, Yuning Liao, Yuan Liu, Jinchan He, Zhenlong Shao, Tumei Hu, Cuifu Yu, Lili Jiang, Jinbao Liu, Hongbiao Huang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-15 (2021)
Abstract Breast cancer has the highest incidence and mortality in women worldwide. There are 70% of breast cancers considered as estrogen receptor α (ERα) positive. Therefore, the ERα-targeted therapy has become one of the most effective solution
Externí odkaz:
https://doaj.org/article/cdfefd67067246128aaa0f758437da76
Autor:
Yufan Tan, Xiaoyu Zhong, Xizhi Wen, Leyi Yao, Zhenlong Shao, Wenshuang Sun, Jiawen Wu, Guanmei Wen, Daolin Tang, Xiaoshi Zhang, Yuning Liao, Jinbao Liu
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Melanoma, the most threatening cancer in the skin, has been considered to be driven by the carcinogenic RAF-MEK1/2-ERK1/2 signaling pathway. This signaling pathway is usually mainly dysregulated by mutations in BRAF or RAS in skin melanomas. Although
Externí odkaz:
https://doaj.org/article/cd8d33404e8248769e4d8de07d19f8a8
Autor:
Ningning Liu, Jinchan He, Xiaohong Xia, Cuifu Yu, Tumei Hu, Qiong Xu, Xiaolin Liu, Hongbiao Huang, Yuning Liao, Bin Liu, Zhenlong Shao
Publikováno v:
International Journal of Biological Sciences
The incidence and mortality of breast cancer (BCa) are the highest among female cancers. There are approximate 70% BCa that are classified as estrogen receptor alpha (ERα) positive. Therefore, targeting ERα is the most significantly therapeutic sch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e31d4e99dd177825faf06fe179c2aa59
https://doi.org/10.7150/ijbs.44005
https://doi.org/10.7150/ijbs.44005
Autor:
Zhenlong Shao, Hongbiao Huang, Jinchan He, Jinbao Liu, Daolin Tang, Xiaohong Xia, Yuan Liu, Chuyi Huang, Lili Jiang, Yuning Liao
Publikováno v:
Theranostics
Rationale: Androgen receptor splice variant 7 (AR-V7) is a leading cause of the development of castration-resistant prostate cancer (CRPC). However, the regulation and function of AR-V7 at levels of post-translational modifications in prostate cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b9a828cb8de58183c7b281e6d19c945
https://doi.org/10.7150/thno.41849
https://doi.org/10.7150/thno.41849
Autor:
Yuning Liao, Wenshuang Sun, Zhenlong Shao, Yuan Liu, Xiaoyu Zhong, Yuanfei Deng, Fang Liu, Hongbiao Huang, Jinbao Liu
Publikováno v:
International journal of biological sciences. 18(6)
Prostate cancer (PC) remains a great medical challenge due to its high incidence and the development of castration resistance in patients treated with androgen deprivation therapy. Deubiquitinases, the enzymes that specifically hydrolyze ubiquitin ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d0a72d0b22cdcabc81f1b163118eca7
https://pubmed.ncbi.nlm.nih.gov/35414775
https://pubmed.ncbi.nlm.nih.gov/35414775
Autor:
Tumei Hu, Yuning Liao, Yuan Liu, Xiaoyue He, Zhenlong Shao, Xiaohong Xia, Hongbiao Huang, Weiyao Kong, Wenshuang Sun, Yuanfei Deng, Cuifu Yu
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 10, Pp 1-13 (2021)
Cell Death and Disease, Vol 12, Iss 10, Pp 1-13 (2021)
Androgen receptor splice variant 7 (AR-V7), a form of ligand-independent and constitutively activating variant of androgen receptor (AR), is considered as the key driver to initiate castration-resistant prostate cancer (CRPC). Because AR-V7 lacks lig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de9f8fcc5ea81ce9220cdea98952eabd
https://doi.org/10.1038/s41419-021-04162-0
https://doi.org/10.1038/s41419-021-04162-0
Autor:
Hongbiao Huang, Yuanfei Deng, Cuifu Yu, Yuning Liao, Fang Liu, Zhiqiang Guo, Wenshuang Sun, Weiyao Kong, Yuan Liu, Xiaohong Xia, Guoxing Chen, Jinbao Liu, Daolin Tang, Zhenlong Shao, Huoye Gan, Xiaoyue He
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-16 (2021)
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-16 (2021)
Background Hepatocellular carcinoma (HCC) remains a medical challenge due to its high proliferation and metastasis. Although deubiquitinating enzymes (DUBs) play a key role in regulating protein degradation, their pathological roles in HCC have not b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c375bc5e642c8f5fa987f31b330fa6a7
https://doi.org/10.1186/s13046-021-02008-3
https://doi.org/10.1186/s13046-021-02008-3
Autor:
Hongbiao Huang, Yuning Liao, Jinchan He, Yuanfei Deng, Cuifu Yu, Jianyu Cai, Tumei Hu, Jinbao Liu, Daolin Tang, Wenshuang Sun, Leyi Yao, Xiaohong Xia, Zhenlong Shao, Fang Liu, Yuan Liu
Publikováno v:
Oncogene. 40(25)
Prostate cancer (PC) is the second most common cancer with limited treatment option in males. Although the reactivation of embryonic signals in adult cells is one of the characteristics of cancer, the underlying protein degradation mechanism remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2559f672da47253ad397d7182201d4e
https://pubmed.ncbi.nlm.nih.gov/34633210
https://pubmed.ncbi.nlm.nih.gov/34633210