Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Zhenkun Na"'
Unannotated microprotein EMBOW regulates the interactome and chromatin and mitotic functions of WDR5
Autor:
Yanran Chen, Haomiao Su, Jianing Zhao, Zhenkun Na, Kevin Jiang, Antonella Bacchiocchi, Ken H. Loh, Ruth Halaban, Zhentian Wang, Xiongwen Cao, Sarah A. Slavoff
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113145- (2023)
Summary: The conserved WD40-repeat protein WDR5 interacts with multiple proteins both inside and outside the nucleus. However, it is currently unclear whether and how the distribution of WDR5 between complexes is regulated. Here, we show that an unan
Externí odkaz:
https://doaj.org/article/677a2dd973a34f00ba7e7ac83d8ed9a4
Autor:
Xiongwen Cao, Alexandra Khitun, Yang Luo, Zhenkun Na, Thitima Phoodokmai, Khomkrit Sappakhaw, Elizabeth Olatunji, Chayasith Uttamapinant, Sarah A. Slavoff
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Many alternative ORFs are co-encoded with characterized proteins, but their function is often not understood. Here, the authors discover that ribosomal protein L36 is co-encoded with alternative protein, which they identify as an upstream regulator o
Externí odkaz:
https://doaj.org/article/091905a115924482b3ee4fbf7e8b7e99
Autor:
Xiaoyun Dai, Jonathan J. Park, Yaying Du, Zhenkun Na, Stanley Z. Lam, Ryan D. Chow, Paul A. Renauer, Jianlei Gu, Shan Xin, Zhiyuan Chu, Cun Liao, Paul Clark, Hongyu Zhao, Sarah Slavoff, Sidi Chen
Publikováno v:
Nature Biotechnology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b622480f20164e56bdfb5b973a0e03c1
https://doi.org/10.1038/s41587-022-01639-x
https://doi.org/10.1038/s41587-022-01639-x
Autor:
Sarah A. Slavoff, Matthew D. Simon, Sowndarya Muthukumar, Alexandra Khitun, Yang Luo, Jeremy A. Schofield, Zhenkun Na, Stephanie Smelyansky, Eugene Valkov
Publikováno v:
Biochemistry
Proteogenomic identification of translated small open reading frames in human has revealed thousands of microproteins, or polypeptides of fewer than 100 amino acids, that were previously invisible to geneticists. Hundreds of microproteins have been s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45248573e9d6416fc7b5fc4f8caaa35d
https://doi.org/10.1021/acs.biochem.0c00672
https://doi.org/10.1021/acs.biochem.0c00672
Autor:
Yanran Chen, Xiongwen Cao, Haomiao Su, Zhenkun Na, Kevin Jiang, Antonella Bacchiocchi, Ken H. Loh, Ruth Halaban, Sarah Slavoff
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::624ba3ab9b9b3fb799d0bc8364662610
https://doi.org/10.2139/ssrn.4283173
https://doi.org/10.2139/ssrn.4283173
Mapping subcellular localizations of unannotated microproteins and alternative proteins with MicroID
Autor:
Zhenkun Na, Xiaoyun Dai, Shu-Jian Zheng, Carson J. Bryant, Ken H. Loh, Haomiao Su, Yang Luo, Amber F. Buhagiar, Xiongwen Cao, Susan J. Baserga, Sidi Chen, Sarah A. Slavoff
Publikováno v:
Molecular cell. 82(15)
Proteogenomic identification of translated small open reading frames has revealed thousands of previously unannotated, largely uncharacterized microproteins, or polypeptides of less than 100 amino acids, and alternative proteins (alt-proteins) that a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a0a3fb5d7d397b7806ffc02de686877
https://pubmed.ncbi.nlm.nih.gov/35905735
https://pubmed.ncbi.nlm.nih.gov/35905735
Autor:
Alexandra Khitun, Stephanie Smelyansky, Yang Luo, D.S. Cui, Sarah A. Slavoff, J. Patrick Loria, Zhenkun Na
Publikováno v:
J Am Chem Soc
Proteogenomic identification of translated small open reading frames in humans has revealed thousands of microproteins, or polypeptides of fewer than 100 amino acids, that were previously invisible to geneticists. Hundreds of microproteins have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9d3a5149df353663f2fce014a84a405
https://pubmed.ncbi.nlm.nih.gov/34651502
https://pubmed.ncbi.nlm.nih.gov/34651502
Autor:
J. Patrick Loria, DanicaS. Cui, Stephanie Smelyansky, Sarah A. Slavoff, Alexandra Khitun, Zhenkun Na, Yang Luo
This study reports detection of specific phosphorylation sites installed on a small open reading frame-encoded polypeptide or microprotein called NBDY. NBDY phosphorylation sites were mapped using phosphoproteomics and antibody-based validation. NBDY
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb57555523f2d201779b9a061d2a5d83
https://doi.org/10.26434/chemrxiv.14632611
https://doi.org/10.26434/chemrxiv.14632611
Autor:
Elizabeth Olatunji, Thitima Phoodokmai, Zhenkun Na, Sarah A. Slavoff, Khomkrit Sappakhaw, Yang Luo, Alexandra Khitun, Chayasith Uttamapinant, Xiongwen Cao
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications
Thousands of human small and alternative open reading frames (smORFs and alt-ORFs, respectively) have recently been annotated. Many alt-ORFs are co-encoded with canonical proteins in multicistronic configurations, but few of their functions are known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::689ba14cf3e8e84bbf90f992481ad8cd
https://doi.org/10.1038/s41467-020-20841-6
https://doi.org/10.1038/s41467-020-20841-6
Publikováno v:
Cell Chem Biol
Dcp2 is an important enzyme that controls the stability of a subset of human cellular RNAs encoding functions such as transcription and immune responses. While >1800 Dcp2 substrates have been identified in human cells, compensatory gene expression ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40779dc3acce5014f9c985d0f3a2f151
https://doi.org/10.26434/chemrxiv.12233102
https://doi.org/10.26434/chemrxiv.12233102