Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Zhenkun Hu"'
Autor:
Samantha K. Sarkar, Angela Matyas, Ikhuosho Asikhia, Zhenkun Hu, Mia Golder, Kaitlyn Beehler, Tanja Kosenko, Thomas A. Lagace
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Proprotein convertase subtilisin/kexin type-9 (PCSK9) is a secreted protein that binds and mediates endo-lysosomal degradation of low-density lipoprotein receptor (LDLR), limiting plasma clearance of cholesterol-rich LDL particles in liver. Gain-of-f
Externí odkaz:
https://doaj.org/article/5b011592ba30443bbae7dc2981011534
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Endoplasmic reticulum (ER) stress promotes cardiac dysfunction. Here the authors uncover a pathway whereby AGGF1 blocks ER stress by inhibiting ERK1/2 activation and the transcriptional repressor ZEB1, leading to induction of miR-183-5p and down-regu
Externí odkaz:
https://doaj.org/article/6125403f9aea40e3becc9eae807175b5
Autor:
Yufeng Yao, Zhenkun Hu, Jian Ye, Changqing Hu, Qixue Song, Xingwen Da, Yubin Yu, Hui Li, Chengqi Xu, Qiuyun Chen, Qing Kenneth Wang
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 6 (2017)
BackgroundDespite recent improvements in angioplasty and placement of drug‐eluting stents in treatment of atherosclerosis, restenosis and in‐stent thrombosis impede treatment efficacy and cause numerous deaths. Research efforts are needed to iden
Externí odkaz:
https://doaj.org/article/66e7a2e14b97451d970780313bb15775
Autor:
Qiulun Lu, Yufeng Yao, Zhenkun Hu, Changqing Hu, Qixue Song, Jian Ye, Chengqi Xu, Annabel Z Wang, Qiuyun Chen, Qing Kenneth Wang
Publikováno v:
PLoS Biology, Vol 14, Iss 8, p e1002529 (2016)
AGGF1 is an angiogenic factor with therapeutic potential to treat coronary artery disease (CAD) and myocardial infarction (MI). However, the underlying mechanism for AGGF1-mediated therapeutic angiogenesis is unknown. Here, we show for the first time
Externí odkaz:
https://doaj.org/article/cb1cb9e8602444b68f986e237e79e22a
Autor:
Yufeng Huang, Chuchu Wang, Yufeng Yao, Xiaoyu Zuo, Shanshan Chen, Chengqi Xu, Hongfu Zhang, Qiulun Lu, Le Chang, Fan Wang, Pengxia Wang, Rongfeng Zhang, Zhenkun Hu, Qixue Song, Xiaowei Yang, Cong Li, Sisi Li, Yuanyuan Zhao, Qin Yang, Dan Yin, Xiaojing Wang, Wenxia Si, Xiuchun Li, Xin Xiong, Dan Wang, Yuan Huang, Chunyan Luo, Jia Li, Jingjing Wang, Jing Chen, Longfei Wang, Li Wang, Meng Han, Jian Ye, Feifei Chen, Jingqiu Liu, Ying Liu, Gang Wu, Bo Yang, Xiang Cheng, Yuhua Liao, Yanxia Wu, Tie Ke, Qiuyun Chen, Xin Tu, Robert Elston, Shaoqi Rao, Yanzong Yang, Yunlong Xia, Qing K Wang
Publikováno v:
PLoS Genetics, Vol 11, Iss 8, p e1005393 (2015)
Atrial fibrillation (AF) is the most common cardiac arrhythmia at the clinic. Recent GWAS identified several variants associated with AF, but they account for
Externí odkaz:
https://doaj.org/article/f5b3f02958594105930ab680c39e4100
Autor:
Zhu Lin, Zhenkun Huang, Jiliang Qiu, Yunxing Shi, Dinglan Zuo, Zhiyu Qiu, Wei He, Yi Niu, Yunfei Yuan, Binkui Li
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-18 (2024)
Abstract Background The escalating prevalence of metabolic diseases has led to a rapid increase in non-alcoholic steatohepatitis (NASH)-related hepatocellular carcinoma (NASH-HCC). While oxaliplatin (OXA)-based hepatic arterial infusion chemotherapy
Externí odkaz:
https://doaj.org/article/964523ec79474b6f96431b8f37d1cace
Autor:
Aijie Liu, Zhenkun Huang, Xiangfu Du, Naresh Duvva, Yuting Du, Zihao Teng, Zhihuan Liao, Chen Liu, Haining Tian, Shuaidong Huo
Publikováno v:
Advanced Science, Vol 11, Iss 35, Pp n/a-n/a (2024)
Abstract The constrained effectiveness of photodynamic therapy (PDT) has impeded its widespread use in clinical practice. Urgent efforts are needed to address the shortcomings faced in photodynamic therapy, such as photosensitizer toxicity, short hal
Externí odkaz:
https://doaj.org/article/aa05f3f5aee34e34b53e6dedf4ed3cd4
Autor:
Sarkar, Samantha K., Matyas, Angela, Ikhuosho Asikhia, Zhenkun Hu, Golder, Mia, Beehler, Kaitlyn, Kosenko, Tanja, Lagace, Thomas A.
Publikováno v:
Frontiers in Physiology; 9/14/2022, Vol. 13, p1-13, 13p
Publikováno v:
International Communications in Heat and Mass Transfer. 133:105981
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c7d2d995643170151b36d832ee788f0
https://doi.org/10.1016/j.icheatmasstransfer.2022.105981
https://doi.org/10.1016/j.icheatmasstransfer.2022.105981
Autor:
Liang Qiao, Wei He, Guoying Wang, Huanwei Chen, Fuxi Huang, Bo Zhang, Yuxiong Qiu, Shaoru Liu, Zhenkun Huang, Yichuan Yuan, Jiliang Qiu, Yunfei Yuan, Binkui Li
Publikováno v:
Cancer Medicine, Vol 13, Iss 9, Pp n/a-n/a (2024)
Abstract Introduction Regorafenib remains the standard and widely used second‐line strategy for advanced hepatocellular carcinoma (HCC). There is still a lack of large‐scale multicenter real‐world evidence concerning the concurrent use of regor
Externí odkaz:
https://doaj.org/article/d7b100f5750b4f9486922d99dd9bd705