Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Zhenhui, Lu"'
Autor:
Nan Zhang, Xu Yang, Mingjian Piao, Ziyu Xun, Yunchao Wang, Cong Ning, Xinmu Zhang, Longhao Zhang, Yanyu Wang, Shanshan Wang, Jiashuo Chao, Zhenhui Lu, Xiaobo Yang, Hanping Wang, Haitao Zhao
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-22 (2024)
Abstract Systemic therapies using programmed death-1 (PD-1) and programmed death ligand 1 (PD-L1) inhibitors have demonstrated commendable efficacy in some patients with advanced hepatocellular carcinoma (HCC); however, other individuals do not respo
Externí odkaz:
https://doaj.org/article/a79bfe8e5e4c47b2b9a876ec1ee87865
Genomic characterization and immunotherapy for microsatellite instability-high in cholangiocarcinoma
Autor:
Xu Yang, Baofeng Lian, Nan Zhang, Junyu Long, Yiran Li, Jingnan Xue, Xiangqi Chen, Yunchao Wang, Yanyu Wang, Ziyu Xun, Mingjian Piao, Chenpei Zhu, Shanshan Wang, Huishan Sun, Zhijian Song, Leilei Lu, Xiaowei Dong, Aodi Wang, Wenjin Liu, Jie Pan, Xiaorong Hou, Mei Guan, Li Huo, Jie Shi, Haohai Zhang, Jinxue Zhou, Zhenhui Lu, Yilei Mao, Xinting Sang, Liqun Wu, Xiaobo Yang, Kai Wang, Haitao Zhao
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Microsatellite instability-high (MSI-H) is a unique genomic status in many cancers. However, its role in the genomic features and immunotherapy in cholangiocarcinoma (CCA) is unclear. This study aimed to systematically investigate
Externí odkaz:
https://doaj.org/article/e96e78be7cfb426197e9dec8e4c18944
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
BackgroundThe coexistence of diabetes mellitus (DM) and pulmonary tuberculosis (PTB) poses a significant health concern globally, with their convergence presenting a considerable challenge to healthcare systems. Previous research has highlighted that
Externí odkaz:
https://doaj.org/article/5e0fdca0da3f48fa9eab1ab04a776ebf
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 18, Iss 1, Pp 1-12 (2023)
Abstract Background Mesenchymal stem cells (MSCs)-based therapy offers an effective strategy for bone regeneration to solve the clinical orthopedic problems. However, the transcriptional regulation of multiple transitional stages of continuous osteog
Externí odkaz:
https://doaj.org/article/596a2977383e42139311ae59776225fb
Publikováno v:
Applied Sciences, Vol 14, Iss 8, p 3240 (2024)
This study exhibits the possibility of using an artificial neural network (ANN) to model the mechanical behavior of wire arc additive manufacturing (WAAM) for Inconel 625. For this reason, tensile tests of Inconel 625 superalloy as-built (AB) samples
Externí odkaz:
https://doaj.org/article/b9925798818b42d4816b97e5017bf702
Publikováno v:
Asian Journal of Surgery, Vol 46, Iss 4, Pp 1819-1821 (2023)
Externí odkaz:
https://doaj.org/article/071510ad80a14985b6589527cf3e0eb5
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-15 (2022)
Abstract Excessive reactive oxygen species (ROS) are one of the leading mechanisms in the initiation and development of osteoarthritis (OA). However, conventional injection of ROS-responsive drug delivery systems (DDSs) such as nanoparticles and hydr
Externí odkaz:
https://doaj.org/article/1b62eb4173e34f02a781d5e15d1ec57b
Autor:
Fucun Xie, Bowen Chen, Xu Yang, Huaiyuan Wang, Ge Zhang, Yanyu Wang, Yunchao Wang, Nan Zhang, Jingnan Xue, Junyu Long, Yiran Li, Huishan Sun, Ziyu Xun, Kai Liu, Xiangqi Chen, Yang Song, Xiaobo Yang, Zhenhui Lu, Yilei Mao, Xinting Sang, Yinying Lu, Haitao Zhao
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundLenvatinib is a standard first-line systemic therapy in advanced hepatocellular carcinoma (aHCC) and is widely used in all lines. However, the efficacy and safety of immune checkpoint inhibitors (ICIs) plus molecular targeted agents (MTAs)
Externí odkaz:
https://doaj.org/article/fb348bd807e94787ae9b086c23530270
Autor:
Ziwei Hu, Jianwen Cheng, Sheng Xu, Xiaojing Cheng, Jinmin Zhao, Zhi Wei Kenny Low, Pei Lin Chee, Zhenhui Lu, Li Zheng, Dan Kai
Publikováno v:
Materials Today Bio, Vol 16, Iss , Pp 100431- (2022)
Hydrogels composed from biomolecules have gained great interests as biomaterials for tissue engineering. However, their poor mechanical properties limit their application potential. Here, we synthesized a series of tough composite hydrogels from poly
Externí odkaz:
https://doaj.org/article/9c3185253fcf4a83bc1fa47c11eee0ee
Autor:
Li Tian, Wei Zhou, Xianwei Wu, Zhuannan Hu, Lei Qiu, Huiyong Zhang, Xue Chen, Shaoyan Zhang, Zhenhui Lu
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Many microbial pathogens have evolved a range of capabilities to evade host immune defense mechanisms and to survive and multiply in host cells. The presence of host intracellular bacteria makes it difficult for specific antibodies to function. After
Externí odkaz:
https://doaj.org/article/876805f902684c128482ff33d920bd15