Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Zhenhua Shan"'
Autor:
Daowei Huang, Jixia Yang, Qingwei Zhang, Xiaolei Zhou, Yanbo Wang, Zhenhua Shang, Jianqi Li, Baoyin Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionPhosphoinositide-3-kinase (PI3K) is overexpressed in many tumors and is, thus, an ideal target for cancer treatments. Accordingly, there is an urgent need for the development of PI3K inhibitors with high potency and low toxicity.MethodsIn
Externí odkaz:
https://doaj.org/article/444aa83e146344c69d2627ca8783b918
A DNase-mimetic artificial enzyme for the eradication of drug-resistant bacterial biofilm infections
Publikováno v:
Nanoscale. 14(7)
The construction of multifunctional nano-enzymes is a feasible strategy for fighting multi-drug resistant (MDR) bacterial biofilm-associated infections. Extracellular DNA (eDNA) is an important functional part of biofilm formation, including the init
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2847faec636f5aa0be87d46456a3495
https://pubmed.ncbi.nlm.nih.gov/35107481
https://pubmed.ncbi.nlm.nih.gov/35107481
Autor:
Guixian Hu, Annabel Igonin, Leigh Ford, Peter J. Scammells, Paolo Botti, Hywel David Williams, Zhenhua Shan, Michael M. Morgen, Hassan Benameur, Christopher J.H. Porter, Colin W. Pouton
Publikováno v:
Advanced Drug Delivery Reviews. 142:75-90
Lipid-based formulations (LBF) are widely used by industry and accepted by the regulatory authorities for oral drug delivery in the pharmaceutical and consumer healthcare market. Innovation in the LBF field is however needed in order to meet the dema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07125d6941f0a73eeb79b839bd7ae3ef
https://doi.org/10.1016/j.addr.2019.05.008
https://doi.org/10.1016/j.addr.2019.05.008
Publikováno v:
Analytical Methods; 1/28/2022, Vol. 14 Issue 4, p460-468, 9p
Publikováno v:
PeerJ, Vol 11, p e16042 (2023)
Background Neurogenic bladder (NB) following suprasacral spinal cord injury (SSCI) is an interstitial disease with the structural remodeling of bladder tissue and matrix over-deposition. Circular RNAs (circRNAs) are involved in fibrotic disease devel
Externí odkaz:
https://doaj.org/article/7fab534edf024955bdc6a47d9d9a8668
Autor:
Daowei Huang, Ying Chen, Jixia Yang, Bingyang Zhao, Shouying Wang, Tingting Chai, Jie Cui, Xiaolei Zhou, Zhenhua Shang
Publikováno v:
Molecules, Vol 29, Iss 2, p 475 (2024)
Mer and c-Met kinases, which are commonly overexpressed in various tumors, are ideal targets for the development of antitumor drugs. This study focuses on the design, synthesis, and evaluation of several 2-substituted aniline pyrimidine derivatives a
Externí odkaz:
https://doaj.org/article/81b5882a020e4ca78f9ba1b113c2db8a
Autor:
Zhenhua Shang, David J. Horovitz, Ronald H. McKenzie, Jessica L. Keisler, Michael R. Felder, Shannon W. Davis
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-17 (2020)
Abstract Background Peromyscus are the most common mammalian species in North America and are widely used in both laboratory and field studies. The deer mouse, P. maniculatus and the old-field mouse, P. polionotus, are closely related and can generat
Externí odkaz:
https://doaj.org/article/42e7c17425fd470e967ee83f17af63cf
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Background: The purpose of this study was to analyze the values of pretreatment serum inflammation markers, lipid, and lipoprotein for predicting the pathological results in men with total prostate-specific antigen between 4 and 10 ng/ml.Materials an
Externí odkaz:
https://doaj.org/article/434dd98169574f2b851fde89a62f9e27
Autor:
Zhenhua Shang, Xue Wang, Hao Yan, Bo Cui, Qi Wang, Jiangtao Wu, Xin Cui, Jin Li, Tongwen Ou, Kun Yang
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Background: Epidemiological evidences regarding the association between the use of non-steroidal anti-inflammatory drugs (NSAIDs) and the risk of prostate cancer (PC) is still controversial. Therefore, we conducted a meta-analysis to explore the cont
Externí odkaz:
https://doaj.org/article/ad3abb9c4edc43eb9490bd8629839e7b
Publikováno v:
Acta Crystallographica Section E, Vol 68, Iss 10, Pp o2853-o2853 (2012)
In the title compound, C26H31NO3, the octahydro-1H-isoindole ring is not planar and the two rings are twisted with a C—C—C—C torsion angle of 73.6 (4)°. The six-membered ring has a chair conformation while the five-membered ring has an envelop
Externí odkaz:
https://doaj.org/article/bf8d402874c2429bad4fd72518f32d37