Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Zhenheng Qin"'
Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly
Autor:
Xinrui Gui, Feng Luo, Yichen Li, Heng Zhou, Zhenheng Qin, Zhenying Liu, Jinge Gu, Muyun Xie, Kun Zhao, Bin Dai, Woo Shik Shin, Jianhua He, Lin He, Lin Jiang, Minglei Zhao, Bo Sun, Xueming Li, Cong Liu, Dan Li
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Low complexity (LC) domains can drive the formation of both amyloid fibrils and protein droplets. Here, the authors identify reversible amyloid cores from the LC of hnRNPA1, based on which they elucidate the structural basis of reversible fibrillatio
Externí odkaz:
https://doaj.org/article/a160475f7cbf47d1b2ddb73a38f8b907
Autor:
Zhenheng Qin, Lulu Bi, Xi-Miao Hou, Siqi Zhang, Xia Zhang, Ying Lu, Ming Li, Mauro Modesti, Xu-Guang Xi, Bo Sun
Publikováno v:
eLife, Vol 9 (2020)
BLM is a multifunctional helicase that plays critical roles in maintaining genome stability. It processes distinct DNA substrates, but not nicked DNA, during many steps in DNA replication and repair. However, how BLM prepares itself for diverse funct
Externí odkaz:
https://doaj.org/article/9ddd44bbe61043f6800b40aa02f180a5
Autor:
Lulu Bi, Zhenheng Qin, Teng Wang, Yanan Li, Xinshuo Jia, Xia Zhang, Xi-Miao Hou, Mauro Modesti, Xu-Guang Xi, Bo Sun
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (23), pp.e2116462119. ⟨10.1073/pnas.2116462119⟩
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (23), ⟨10.1073/pnas.2116462119⟩
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (23), pp.e2116462119. ⟨10.1073/pnas.2116462119⟩
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (23), ⟨10.1073/pnas.2116462119⟩
International audience; Helicases are multifunctional motor proteins with the primary task of separating nucleic acid duplexes. These enzymes often exist in distinct oligomeric forms and play essential roles during nucleic acid metabolism. Whether th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a88396bf6b9ee6eb46a2ef7d21c081d
https://www.hal.inserm.fr/inserm-03825786
https://www.hal.inserm.fr/inserm-03825786
Publikováno v:
Optical Tweezers ISBN: 9781071622285
Optical Tweezers
Optical Tweezers, 2478, Springer US, pp.329-347, 2022, Methods in Molecular Biology, ⟨10.1007/978-1-0716-2229-2_12⟩
Optical Tweezers
Optical Tweezers, 2478, Springer US, pp.329-347, 2022, Methods in Molecular Biology, ⟨10.1007/978-1-0716-2229-2_12⟩
International audience; Helicases are ubiquitous molecular motor proteins that utilize the energy derived from the hydrolysis of nucleoside triphosphates (NTPs) to transiently convert the duplex form of nucleic acids to single-stranded intermediates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f37eb9e41587b5bad1f637a5a9530f
https://doi.org/10.1007/978-1-0716-2229-2_12
https://doi.org/10.1007/978-1-0716-2229-2_12
Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly
Autor:
Minglei Zhao, Jianhua He, Lin Jiang, Xueming Li, Zhenheng Qin, Muyun Xie, Bo Sun, Woo Shik Shin, Zhenying Liu, Jinge Gu, Xinrui Gui, Kun Zhao, Heng Zhou, Bin Dai, Dan Li, Yang Li, Cong Liu, Lin He, Feng Luo
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Subcellular membrane-less organelles consist of proteins with low complexity domains. Many of them, such as hnRNPA1, can assemble into both a polydisperse liquid phase and an ordered solid phase of amyloid fibril. The former mirrors biological granul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9965c8533765fd5283d03fc717317810
https://doaj.org/article/a160475f7cbf47d1b2ddb73a38f8b907
https://doaj.org/article/a160475f7cbf47d1b2ddb73a38f8b907
Autor:
Xu-Guang Xi, Ming Li, Zhenheng Qin, Bo Sun, Xi-Miao Hou, Siqi Zhang, Ying Lu, Mauro Modesti, Xia Zhang, Lulu Bi
Publikováno v:
eLife
eLife, eLife Sciences Publication, 2020, 9, ⟨10.7554/eLife.54098⟩
eLife, Vol 9 (2020)
eLife, 2020, 9, ⟨10.7554/eLife.54098⟩
eLife, 2020, 9, ⟨10.7554/elife.54098⟩
eLife, eLife Sciences Publication, 2020, 9, ⟨10.7554/elife.54098⟩
eLife, eLife Sciences Publication, 2020, 9, ⟨10.7554/eLife.54098⟩
eLife, Vol 9 (2020)
eLife, 2020, 9, ⟨10.7554/eLife.54098⟩
eLife, 2020, 9, ⟨10.7554/elife.54098⟩
eLife, eLife Sciences Publication, 2020, 9, ⟨10.7554/elife.54098⟩
International audience; BLM is a multifunctional helicase that plays critical roles in maintaining genome stability. It processes distinct DNA substrates, but not nicked DNA, during many steps in DNA replication and repair. However, how BLM prepares
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::314aa2b62a559e8f8de023baae16e057
https://hal.archives-ouvertes.fr/hal-03038384
https://hal.archives-ouvertes.fr/hal-03038384