Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Zhenheng Guo"'
CD47 antisense oligonucleotide treatment attenuates obesity and its-associated metabolic dysfunction
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Previous study from our lab has revealed a new role of CD47 in regulating adipose tissue function, energy homeostasis and the development of obesity and metabolic disease in CD47 deficient mice. In this study, the therapeutic potential of an
Externí odkaz:
https://doaj.org/article/492d20b1f9a0429bb6bb74f243acd429
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
Disruption of blood pressure (BP) circadian rhythm, independent of hypertension, is emerging as an index for future target organ damage and is associated with a higher risk of cardiovascular events. Previous studies showed that changing food availabi
Externí odkaz:
https://doaj.org/article/f90875bd9dc04882b46d691bea0665be
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
People with diabetes are more likely to experience sleep disturbance than those without. Sleep disturbance can cause daytime sleepiness in diabetic patients, which may impair their daytime performance or even lead to workplace injuries. Therefore, re
Externí odkaz:
https://doaj.org/article/19bd89082c7a41f09e1b8c083e58d574
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31850 (2012)
Calcium independent group VIA phospholipase A(2) (iPLA(2)β) is up-regulated in vascular smooth muscle cells in some diseases, but whether the up-regulated iPLA(2)β affects vascular morphology and blood pressure is unknown. The current study address
Externí odkaz:
https://doaj.org/article/b199196c0a4741a0b7e650ef2de2af2d
Autor:
Xufang Mu, Shu Liu, Zhuoran Wang, Kai Jiang, Tim McClintock, Arnold J. Stromberg, Alejandro V. Tezanos, Eugene S Lee, John A. Curci, Ming C Gong, Zhenheng Guo
Publikováno v:
bioRxiv
Androgen has long been recognized for its pivotal role in the sexual dimorphism of cardiovascular diseases, including aortic aneurysms, a devastating vascular disease with a higher prevalence and mortality rate in men than women. However, the molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d1f818f75a2a381c610172d152ce13a
https://doi.org/10.1101/2023.01.22.525073
https://doi.org/10.1101/2023.01.22.525073
Publikováno v:
Curr Opin Pharmacol
The intrinsic vascular smooth muscle contraction and vasoconstriction show time-of-day variations, contributing to the blood pressure circadian rhythm, which is essential for cardiovascular health. This brief review provides an overview of our curren
Autor:
Xufang Mu, Shu Liu, Timothy McClintock, Arnold Stromberg, Alejandro Villasante-Tezanos, Ming C Gong, Zhenheng Guo
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 41
Objective: Male sex is a well-established risk factor for abdominal aortic aneurysms (AAA) but the underlying mechanisms remain to be fully understood. Using an aldosterone and high salt (Aldo/salt) induced AAA mouse model, we have demonstrated that
Publikováno v:
Proc Natl Acad Sci U S A
The quantity and quality of food intake have been considered crucial for peoples' wellness. Only recently has it become appreciated that the timing of food intake is also critical. Nondipping blood pressure (BP) is prevalent in diabetic patients and
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 40:17-19