Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Zhengyu O"'
Autor:
Kejie Li, Yu H. Sun, Zhengyu Ouyang, Soumya Negi, Zhen Gao, Jing Zhu, Wanli Wang, Yirui Chen, Sarbottam Piya, Wenxing Hu, Maria I. Zavodszky, Hima Yalamanchili, Shaolong Cao, Andrew Gehrke, Mark Sheehan, Dann Huh, Fergal Casey, Xinmin Zhang, Baohong Zhang
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Background Single-cell RNA sequencing is a state-of-the-art technology to understand gene expression in complex tissues. With the growing amount of data being generated, the standardization and automation of data analysis are critical to gen
Externí odkaz:
https://doaj.org/article/8f534c5f1fa14c889a7b21ee781902e7
Autor:
Frederike Straeten, Jing Zhu, Anna-Lena Börsch, Baohong Zhang, Kejie Li, I-Na Lu, Catharina Gross, Michael Heming, Xiaolin Li, Rebekah Rubin, Zhengyu Ouyang, Heinz Wiendl, Michael Mingueneau, Gerd Meyer zu Hörste
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-14 (2022)
Abstract Multiple sclerosis (MS) is a chronic and often disabling autoimmune disease of the central nervous system (CNS). Cerebrospinal fluid (CSF) surrounds and protects the CNS. Analysis of CSF can aid the diagnosis of CNS diseases, help to identif
Externí odkaz:
https://doaj.org/article/5750e296d3fc45a9887f830e47edcd66
Autor:
Zhengyu Ouyang, Nathanael Bourgeois-Tchir, Eugenia Lyashenko, Paige E. Cundiff, Patrick F. Cullen, Ravi Challa, Kejie Li, Xinmin Zhang, Fergal Casey, Sandra J. Engle, Baohong Zhang, Maria I. Zavodszky
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Induced pluripotent stem cell (iPSC) derived cell types are increasingly employed as in vitro model systems for drug discovery. For these studies to be meaningful, it is important to understand the reproducibility of the iPSC-derived culture
Externí odkaz:
https://doaj.org/article/bb8dfd950f2a43319b5fd7d678c3f265
Autor:
Enrique Martin-Gayo, Ce Gao, Marta Calvet-Mirabent, Zhengyu Ouyang, Mathias Lichterfeld, Xu G. Yu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionSpontaneous control of HIV-1 replication in the absence of anti-retroviral therapy (ART) naturally occurs in a small proportion of HIV-1-infected individuals known as elite controllers (EC), likely as a result of improved innate and adapt
Externí odkaz:
https://doaj.org/article/d0993bba3c584d35905b779477dfc941
Autor:
Xiaoming Sun, Stephane Hua, Ce Gao, Jane E. Blackmer, Zhengyu Ouyang, Kevin Ard, Andrea Ciaranello, Sigal Yawetz, Paul E. Sax, Eric S. Rosenberg, Mathias Lichterfeld, Xu G. Yu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Zika virus (ZIKV) poses a significant public health threat, but the immune landscape changes following ZIKV infection is still unclear. Here, the authors show, using flow cytometry and transcriptomic data, that ZIKV induces a multitude of immune resp
Externí odkaz:
https://doaj.org/article/22635906b94d4ef385dfa69cc1d812bc
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Jake Gagnon, Lira Pi, Matthew Ryals, Qingwen Wan, Wenxing Hu, Zhengyu Ouyang, Baohong Zhang, Kejie Li
Publikováno v:
Life, Vol 12, Iss 6, p 850 (2022)
To guide analysts to select the right tool and parameters in differential gene expression analyses of single-cell RNA sequencing (scRNA-seq) data, we developed a novel simulator that recapitulates the data characteristics of real scRNA-seq datasets w
Externí odkaz:
https://doaj.org/article/c154c563ce07478f9cfe8b1033529622
Autor:
Patrick Süß, Alana Hoffmann, Tobias Rothe, Zhengyu Ouyang, Wolfgang Baum, Ori Staszewski, Georg Schett, Marco Prinz, Gerhard Krönke, Christopher K. Glass, Jürgen Winkler, Johannes C.M. Schlachetzki
Publikováno v:
Cell Reports, Vol 30, Iss 12, Pp 4082-4095.e6 (2020)
Summary: Systemic immune dysregulation contributes to the development of neuropsychiatric and neurodegenerative diseases. The precise effect of chronic peripheral immune stimulation on myeloid cells across anatomical brain regions is unclear. Here, w
Externí odkaz:
https://doaj.org/article/bd22cf9222c14c19a516a5d90377ff74
Autor:
Enrique Martin-Gayo, Ce Gao, Hsiao Rong Chen, Zhengyu Ouyang, Dhohyung Kim, Kellie E. Kolb, Alex K. Shalek, Bruce D. Walker, Mathias Lichterfeld, Xu G. Yu
Publikováno v:
Cell Reports, Vol 30, Iss 4, Pp 984-996.e4 (2020)
Summary: The induction of broadly neutralizing antibodies (bnAbs) is highly desired for an effective vaccine against HIV-1. Typically, bnAbs develop in patients with high viremia, but they can also evolve in some untreated HIV-1 controllers with low
Externí odkaz:
https://doaj.org/article/b9c90d6ace664376b82c9b173e19b6db