Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Zhengying Su"'
Autor:
Jianyu Liu, Minghai Tang, Tao Li, Zhengying Su, Zejiang Zhu, Caixia Dou, Yan Liu, Heying Pei, Jianhong Yang, Haoyu Ye, Lijuan Chen
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/62b2acb3e46243b9928d4c0135d3e767
Autor:
Jianyu Liu, Minghai Tang, Tao Li, Zhengying Su, Zejiang Zhu, Caixia Dou, Yan Liu, Heying Pei, Jianhong Yang, Haoyu Ye, Lijuan Chen
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Post-myocardial infarction heart failure (post-MI HF) is one of the leading global causes of death, and current prevention and treatment methods still cannot avoid the increasing incidence. Honokiol (HK) has previously been reported to improve myocar
Externí odkaz:
https://doaj.org/article/3e23cf59dba741579293435566af7014
Autor:
Wenting Si, Jiang Liu, Yan Liu, Qiang Qiu, Haoyu Ye, Wanhua Zhang, Lijuan Chen, Zejiang Zhu, Linyu Yang, Jianhong Yang, Shuang Kuang, Zhuang Yang, Minghai Tang, Mingsong Shi, Wei Yan, Zhengying Su, Peng Bai
Publikováno v:
Journal of Medicinal Chemistry. 64:15379-15401
Hydroxamic acid group is one of the characteristic pharmacophores of histone deacetylase (HDAC) inhibitors. But here, we discovered a series of hydroxamic acid-based microtubule destabilizing agents (MDAs), which were derived from shortening the leng
Autor:
Cai-Xia Dou, Li Wan, Hengfan Ni, Xiang Qiu, Lijuan Chen, Zhengying Su, Zhuang Yang, Yong Li, Heying Pei
Publikováno v:
Chemical Biology & Drug Design. 97:358-371
A novel series of Aloe-emodin derivatives containing N-heterocyclic moieties was designed and synthesized. The structure-activity relationship studies (SARs) indicated that the replacement of hydroxyethyl and benzhydryl piperazine groups could improv
Autor:
Zejiang Zhu, Caixia Dou, Lijuan Chen, Qiaoqiao Hu, Peng Bai, Rongsheng Tong, Zhengying Su, Lulu Cai, Bai Lan, Junfeng Yan, Wuyu Zhang, Minghai Tang
Publikováno v:
Chinese Chemical Letters. 31:915-918
β-Elemene is a volatile oil used for the treatment of cancer, but poor solubility, low bioavailability, and various adverse reactions limit its application. For ameliorating risks of the venous toxicity of β-elemene, intravenously injectable micell
Autor:
Jianyu Liu, Minghai Tang, Tao Li, Zhengying Su, Zejiang Zhu, Caixia Dou, Yan Liu, Heying Pei, Jianhong Yang, Haoyu Ye, Lijuan Chen
Publikováno v:
Frontiers in pharmacology. 13
Post-myocardial infarction heart failure (post-MI HF) is one of the leading global causes of death, and current prevention and treatment methods still cannot avoid the increasing incidence. Honokiol (HK) has previously been reported to improve myocar
Autor:
Qiaoqiao Hu, Jiaolin Wen, Ting Niu, Minghai Tang, Zhengying Su, Jun He, Jianhong Yang, Peng Bai, Huili Liu, Zejiang Zhu, Lijuan Chen
Publikováno v:
Journal of Biomedical Nanotechnology. 15:1515-1531
In our previous study, we identified a class of 4-substituted coumarins as a powerful microtubule inhibitors binding to the colchicine site of β-tubulin. H6 showed potent anti-proliferative ability with IC50 values from 7 to 47 nM, and remarkable ab
Autor:
Zhengying Su, Danrong Li, Dandan Liang, Zhaoquan Li, Huaxin Hou, Chunmiao Wang, Wei Tian, Junying Li, Fu Lan
Publikováno v:
ACS Med Chem Lett
[Image: see text] Novel anthraquinone compounds that induce ER stress and paraptosis-like cell death were designed and synthesized. Compound 4a is the first organic micromolecule to kill tumor cells by only paraptosis, and its mechanism of action has
Autor:
Linyu Yang, Wanhua Zhang, Qiang Qiu, Zhengying Su, Minghai Tang, Peng Bai, Wenting Si, Zejiang Zhu, Yan Liu, Jianhong Yang, Shuang Kuang, Jiang Liu, Wei Yan, Mingsong Shi, Haoyu Ye, Zhuang Yang, Lijuan Chen
Publikováno v:
Journal of Medicinal Chemistry. 65:11890-11890
Publikováno v:
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. 36(10)
Objective To establish a triple negative breast cancer cell line stably expressing human epidermal growth factor receptor (EGFR) promoter and luciferase (Luc) reporter gene and to preliminarily verify its application. Methods Using genetic recombinat