Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Zhengye Zhao"'
Autor:
Guozhuang Li, Kexin Xu, Xiangjie Yin, Jianle Yang, Jihao Cai, Xinyu Yang, Qing Li, Jie Wang, Zhengye Zhao, Aoran Mahesahti, Ning Zhang, Terry Jianguo Zhang, Nan Wu
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-7 (2024)
Abstract Phenotypes play a fundamental role in medical genetics, serving as external manifestations of underlying genotypes. Deep phenotyping, a cornerstone of precision medicine, involves precise multi-system phenotype assessments, facilitating dise
Externí odkaz:
https://doaj.org/article/fd75a92a0d754c01b7a0b0048c16eedd
Autor:
Sen Zhao, Hengqiang Zhao, Lina Zhao, Xi Cheng, Zhifa Zheng, Mengfan Wu, Wen Wen, Shengru Wang, Zixiang Zhou, Haibo Xie, Dengfeng Ruan, Qing Li, Xinquan Liu, Chengzhu Ou, Guozhuang Li, Zhengye Zhao, Guilin Chen, Yuchen Niu, Xiangjie Yin, Yuhong Hu, Xiaochen Zhang, Deciphering disorders Involving Scoliosis and COmorbidities (DISCO) study, Pengfei Liu, Guixing Qiu, Wanlu Liu, Chengtian Zhao, Zhihong Wu, Jianguo Zhang, Nan Wu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract Congenital vertebral malformation, affecting 0.13–0.50 per 1000 live births, has an immense locus heterogeneity and complex genetic architecture. In this study, we analyze exome/genome sequencing data from 873 probands with congenital vert
Externí odkaz:
https://doaj.org/article/5d2439648d9a4a0c8a930156c25c0a91
Autor:
Jiaqi Liu, Hengqiang Zhao, Yu Zheng, Lin Dong, Sen Zhao, Yukuan Huang, Shengkai Huang, Tianyi Qian, Jiali Zou, Shu Liu, Jun Li, Zihui Yan, Yalun Li, Shuo Zhang, Xin Huang, Wenyan Wang, Yiqun Li, Jie Wang, Yue Ming, Xiaoxin Li, Zeyu Xing, Ling Qin, Zhengye Zhao, Ziqi Jia, Jiaxin Li, Gang Liu, Menglu Zhang, Kexin Feng, Jiang Wu, Jianguo Zhang, Yongxin Yang, Zhihong Wu, Zhihua Liu, Jianming Ying, Xin Wang, Jianzhong Su, Xiang Wang, Nan Wu
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-15 (2022)
Abstract Background Identifying breast cancer patients with DNA repair pathway-related germline pathogenic variants (GPVs) is important for effectively employing systemic treatment strategies and risk-reducing interventions. However, current criteria
Externí odkaz:
https://doaj.org/article/60de1be1db0e43cdb084be6bde5c2274
Autor:
Nan Wu, Jiashen Shao, Zhen Zhang, Shengru Wang, Ziquan Li, Sen Zhao, Yang Yang, Lian Liu, Chenxi Yu, Sen Liu, Zhengye Zhao, You Du, Yuanqiang Zhang, Lianlei Wang, Yu Zhao, Keyi Yu, Hong Zhao, Jianxiong Shen, Guixing Qiu, Deciphering Disorders Involving Scoliosis and COmorbidities (DISCO) study, Zhihong Wu, Terry Jianguo Zhang
Publikováno v:
BMC Musculoskeletal Disorders, Vol 22, Iss 1, Pp 1-9 (2021)
Abstract Introduction Adult non-degenerative scoliosis accounts for 90% of spinal deformities in young adults. However, perioperative complications and related risk factors of long posterior instrumentation and fusion for the treatment of adult non-d
Externí odkaz:
https://doaj.org/article/f7848b01de9e4d2a96573bdb768135f3
Autor:
Chenxi Yu, Bobo Xie, Zhengye Zhao, Sen Zhao, Lian Liu, Xi Cheng, Xiaoxin Li, Bingyan Cao, Jiashen Shao, Jiajia Chen, Hengqiang Zhao, Zihui Yan, Chang Su, Yuchen Niu, Yanning Song, Liya Wei, Yi Wang, Xiaoya Ren, Lijun Fan, Beibei Zhang, Chuan Li, Baoheng Gui, Yuanqiang Zhang, Lianlei Wang, Shaoke Chen, Jianguo Zhang, Zhihong Wu, Chunxiu Gong, Xin Fan, Nan Wu
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
PurposeCongenital growth hormone deficiency (GHD) is a rare and etiologically heterogeneous disease. We aim to screen disease-causing mutations of GHD in a relatively sizable cohort and discover underlying mechanisms via a candidate gene-based mutati
Externí odkaz:
https://doaj.org/article/a76e8af7593342fb889a7a0b09459c4c
Autor:
Baoheng Gui, Chenxi Yu, Xiaoxin Li, Sen Zhao, Hengqiang Zhao, Zihui Yan, Xi Cheng, Jiachen Lin, Haiyang Zheng, Jiashen Shao, Zhengye Zhao, Lina Zhao, Yuchen Niu, Zhi Zhao, Huizi Wang, Bobo Xie, Xianda Wei, Chunrong Gui, Chuan Li, Shaoke Chen, Yi Wang, Yanning Song, Chunxiu Gong, Terry Jianguo Zhang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
PurposeROR2, a member of the ROR family, is essential for skeletal development as a receptor of Wnt5a. The present study aims to investigate the mutational spectrum of ROR2 in children with short stature and to identify the underlying molecular mecha
Externí odkaz:
https://doaj.org/article/dedeaba4d25c45a883232970fa5d6644
Autor:
Wen Wen, Zhengye Zhao, Zhifa Zheng, Sen Zhao, Hengqiang Zhao, Xi Cheng, Huakang Du, Ziquan Li, Shengru Wang, Guixing Qiu, Zhihong Wu, Terry Jianguo Zhang, Nan Wu
Publikováno v:
Journal of Medical Genetics; Jul2024, Vol. 61 Issue 7, p666-676, 25p
Publikováno v:
Insight - Non-Destructive Testing and Condition Monitoring. 64:334-340
The objective of this research is to investigate the evolution of the piezomagnetic field of 30CrNiMo8 steel under cyclic tensile stress with variable amplitudes and asymmetrical cyclic tensile stress. The piezomagnetic field signal of an initially u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::885c4fb067588cbabff8474db5d87ee4
https://doi.org/10.1784/insi.2022.64.6.334
https://doi.org/10.1784/insi.2022.64.6.334
Autor:
Zefu Chen, Yu Zheng, Yongxin Yang, Yingzhao Huang, Sen Zhao, Hengqiang Zhao, Chenxi Yu, Xiying Dong, Yuanqiang Zhang, Lianlei Wang, Zhengye Zhao, Shengru Wang, Yang Yang, Yue Ming, Jianzhong Su, Guixing Qiu, Zhihong Wu, Terry Jianguo Zhang, Nan Wu
Publikováno v:
Am J Hum Genet
In recent years, exome sequencing (ES) has shown great utility in the diagnoses of Mendelian disorders. However, after rigorous filtering, a typical ES analysis still involves the interpretation of hundreds of variants, which greatly hinders the rapi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a532be7a427f3564e549fa116bde549d
https://doi.org/10.1016/j.ajhg.2021.12.008
https://doi.org/10.1016/j.ajhg.2021.12.008
Publikováno v:
Research in Nondestructive Evaluation. 32:210-222
The goal of this research is to correlate the piezomagnetic field with the stress and the stress concentration degree of ferromagnetic steels. Specimens of X80 steels were machined into smooth plat...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::242366d09d8aa86237b5028be17b69a4
https://doi.org/10.1080/09349847.2021.1963022
https://doi.org/10.1080/09349847.2021.1963022