Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Zhengxing Qu"'
Autor:
Lee M. Greenberger, Ivan D. Horak, Stephen Youngster, Jenny Pak, Ying Gao, Steve Kim, Patricia Kraft, Victoria Shi, Zhengxing Qu, Qi Li, Maoliang Wang, Yixian Zhang, Yaming Wu
Supplementary Figure Legend PDF file - 85K, Figure legend for each supplementary figure.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3275f7dfdad083bbc3e4041d54058250
https://doi.org/10.1158/1535-7163.22498878
https://doi.org/10.1158/1535-7163.22498878
Autor:
Lee M. Greenberger, Ivan D. Horak, Robert L. Vessella, Hong Zhao, Raj Bandaru, Puja Sapra, Jenny Pak, Ying Gao, Patricia Kraft, Victoria Shi, Steven Kim, Zhengxing Qu, Mary Mileski, Maoliang Wang, Melissa Dumble, Stephen Castaneda, Yixian Zhang
PDF file - 304K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::122f845b833c3fd22bfeb72faad78f38
https://doi.org/10.1158/1535-7163.22497225.v1
https://doi.org/10.1158/1535-7163.22497225.v1
Autor:
Patricia Kraft, Raj Bandaru, Victoria Shi, B. Liao, Ivan D. Horak, Zhengxing Qu, Yixian Zhang, Steven Kim, Lee M. Greenberger, Yaming Wu
Publikováno v:
Gene Therapy
Usually, small interfering RNAs and most antisense molecules need mechanical or chemical delivery methods to down-modulate the targeted mRNA. However, these delivery approaches complicate the interpretations of biological consequences. We show that l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8de59eeb8144fe3aabd6d1a458f7e522
http://europepmc.org/articles/PMC3154478
http://europepmc.org/articles/PMC3154478
Autor:
Josette Carnahan, Hans J. Hansen, Alessandra Cesano, Zhengxing Qu, Kristen Hess, Rhona Stein, David M. Goldenberg
Publikováno v:
Molecular Immunology. 44:1331-1341
Epratuzumab is a humanized anti-CD22 monoclonal antibody currently in clinical trials for treatment of non-Hodgkin lymphoma (NHL) and certain autoimmune diseases. Here we report the results of investigations of epratuzumab's mode of action in compari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333c68e15b522e36551bc3746072ba7b
https://doi.org/10.1016/j.molimm.2006.05.007
https://doi.org/10.1016/j.molimm.2006.05.007
Autor:
Adriane V. Rosario, Ivan Horak, Thomas M. Cardillo, Rhona Stein, Susan Chen, Zhengxing Qu, David M. Goldenberg, Hans J. Hansen
Publikováno v:
Blood. 104:3705-3711
The humanized anti-CD74 monoclonal antibody (mAb) hLL1 is under evaluation as a therapeutic agent. The effects of hLL1—at times in comparison with the CD20 mAb rituximab—were assessed on non-Hodgkin lymphoma (NHL) and multiple myeloma (MM) cell l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf9ed6873b72bf4de51806d81dfa92f5
https://doi.org/10.1182/blood-2004-03-0890
https://doi.org/10.1182/blood-2004-03-0890
Autor:
Zhengxing Qu, Hong Ma, Hans J. Hansen, Serengulam V. Govindan, David M. Goldenberg, Rhona Stein, Susan Chen, Gary L. Griffiths, Philip M. Andrews, Ivan Horak
Publikováno v:
Breast Cancer Research and Treatment. 84:173-182
A humanized monoclonal antibody (MAb), hRS7, labeled with 131I-IMP-R4, was evaluated for the preclinical radioimmunotherapy (RAIT) of breast cancer. 131I-IMP-R4 is an improved residualizing form of 131I that overcomes the short tumor residence time a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dcc01d473bdb2f1277f81416a6a57da
https://doi.org/10.1023/b:brea.0000018417.02580.ef
https://doi.org/10.1023/b:brea.0000018417.02580.ef
Autor:
Shui-On Leung, Serengulam V. Govindan, Lisa B. Shih, Hans J. Hansen, David M. Goldenberg, Jian Shen, Robert M. Sharkey, Zhengxing Qu
Publikováno v:
Journal of Immunological Methods. 213:131-144
To improve the efficiency of site-specific conjugation of chelates and drugs to antibodies, and to minimize the incidence of immunoreactivity perturbation to the resultant immunoconjugates, Asn-linked oligosaccharide moieties were designed and engine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f687079d0524382ad27ed0a4e048a03
https://doi.org/10.1016/s0022-1759(97)00192-0
https://doi.org/10.1016/s0022-1759(97)00192-0
Autor:
David M. Goldenberg, Lisa B. Shih, Indira S. Krishnan, Li Zeng, Heather Dworak, Shui-On Leung, Zhengxing Qu, Hans J. Hansen, Michele J. Losman
Publikováno v:
Cancer. 80:2660-2666
BACKGROUND. LL2 is a murine immunoglobulin (Ig)G2a-kappa anti-B-cell monoclonal antibody with proven targeting and therapeutic efficacy in the management of non-Hodgkin's lymphoma (NHL). The authors had previously generated a humanized LL2 (hLL2) tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::156a4b37ff81b0cdf16aa0cecbb2bd14
https://doi.org/10.1002/(sici)1097-0142(19971215)80:12+<2660::aid-cncr43>3.0.co
https://doi.org/10.1002/(sici)1097-0142(19971215)80:12+<2660::aid-cncr43>3.0.co
Publikováno v:
Glycobiology. 7:803-809
Two humanized antibody mutants, hLL2HCN1 and hLL2HCN5, engineered with CH1 domain-appended carbohydrates (CHOs) were generated to facilitate site-specific conjugation of radionuclides and anti-cancer drugs to antibodies. Such site-specific conjugatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e4f5eee46143f3c619af3fc9ab40855
https://doi.org/10.1093/glycob/7.6.803
https://doi.org/10.1093/glycob/7.6.803
Autor:
Victoria Shi, Maoliang Wang, Ying Gao, Qi Li, Yaming Wu, Jenny Pak, Ivan D. Horak, Lee M. Greenberger, Zhengxing Qu, Stephen K. Youngster, Steve Kim, Patricia Kraft, Yixian Zhang
Publikováno v:
Molecular cancer therapeutics. 12(4)
Among the four human EGF receptor (HER) family members (EGFR, HER2, HER3, HER4), HER3 is of particular interest as it interacts with HER2 and EGFR via heterodimerization and is a key link to the phosphoinositide 3-kinase (PI3K)/AKT signal transductio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d6a061e77674d997887b40a57b03cb9
https://pubmed.ncbi.nlm.nih.gov/23395887
https://pubmed.ncbi.nlm.nih.gov/23395887