Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Zhengxi Wei"'
Autor:
Zhengxi Wei, Tuan Xu, Judy Strickland, Li Zhang, Yuhong Fang, Dingyin Tao, Anton Simeonov, Ruili Huang, Nicole C. Kleinstreuer, Menghang Xia
Publikováno v:
Frontiers in Toxicology, Vol 6 (2024)
Introduction: Skin sensitization, which leads to allergic contact dermatitis, is a key toxicological endpoint with high occupational and consumer prevalence. This study optimized several in vitro assays listed in OECD skin sensitization test guidelin
Externí odkaz:
https://doaj.org/article/18a1c8f0daa2490a935d7470c9a49342
Publikováno v:
Water, Vol 15, Iss 8, p 1472 (2023)
As wastewater treatment usually involves complicated biochemical reactions, leading to strong coupling correlation and nonlinearity in water quality parameters, it is difficult to analyze and optimize the control of the wastewater treatment plant (WW
Externí odkaz:
https://doaj.org/article/f4db69d9615041229686ec58ee78808c
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Mitochondria are essential cellular organelles that participate in important cellular processes, including bioenergetics, metabolism, and signaling. Recent functional and proteomic studies have revealed the remarkable complexity of mitochondrial prot
Externí odkaz:
https://doaj.org/article/684b196d0ff64797bee0c4225d486936
Autor:
Zhengxi Wei, Xue Liu, Masato Ooka, Li Zhang, Min Jae Song, Ruili Huang, Nicole C. Kleinstreuer, Anton Simeonov, Menghang Xia, Marc Ferrer
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Assessing skin irritation potential is critical for the safety evaluation of topical drugs and other consumer products such as cosmetics. The use of advanced cellular models, as an alternative to replace animal testing in the safety evaluation for bo
Externí odkaz:
https://doaj.org/article/c74a293094e145e2a89c2fcce252c82b
Autor:
Christopher A. LeClair, Matthew D. Hall, Menghang Xia, Ruili Huang, Zhengxi Wei, Anton Simeonov, Tuan Xu, Qin Yao, Valeriu Cebotaru, Yuhong Fang, Andrew P. Burns, Yaqin Zhang, Dingyin Tao
Publikováno v:
Anal Chem
Major advances have been made to improve the sensitivity of mass analyzers, spectral quality, and speed of data processing enabling more comprehensive proteome discovery and quantitation. While focus has recently begun shifting toward robust proteomi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80dda047ca337a0574a0c2d0462afec4
https://doi.org/10.1021/acs.analchem.1c00265
https://doi.org/10.1021/acs.analchem.1c00265
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2474
The nuclear factor erythroid 2-related factor (Nrf2) and antioxidant response element (ARE) signaling pathway play an important role in the amelioration of cellular oxidative stress. Thus, assays that detect this pathway can be useful for identifying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d4c3430f917d8ea46667fd91fdb60ea
https://pubmed.ncbi.nlm.nih.gov/35294756
https://pubmed.ncbi.nlm.nih.gov/35294756
Publikováno v:
Methods in Molecular Biology ISBN: 9781071622124
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e74624bb6746adb1997e2cd19f41e44
https://doi.org/10.1007/978-1-0716-2213-1_7
https://doi.org/10.1007/978-1-0716-2213-1_7
Autor:
Yuhong Fang, Zhengxi Wei, Dingyin Tao, Anton Simeonov, Maya L. Gosztyla, Christopher A. LeClair, Andrew J. Li, Menghang Xia, Wenwei Huang
Publikováno v:
Toxicol Lett
Chemical-peptide conjugation is the molecular initiating event in skin sensitization. The OECD test guideline uses a high-performance liquid chromatography/ultraviolet (HPLC/UV) detection method to quantify chemical-peptide conjugation in a direct pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f9ae4efbd6fa4b2e90d26b3020f7504
https://europepmc.org/articles/PMC9527016/
https://europepmc.org/articles/PMC9527016/
Publikováno v:
Toxicology and Applied Pharmacology. 356:36-43
Cadmium (Cd) has been linked to a variety of cancers, including breast cancer; however, the molecular mechanism of its carcinogenic activity is not fully understood. To this end, the present study investigated the roles of ferroportin (FPN), a progno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8fc3b65a80a00158f0f4ade05a1c6f6
https://doi.org/10.1016/j.taap.2018.07.017
https://doi.org/10.1016/j.taap.2018.07.017