Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Zhengwu Sun"'
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract Dysfunctional Ca2+ signaling affects the myocardial systole and diastole, may trigger arrhythmia and cause transcriptomic and proteomic modifications in heart failure. Thus, synchronous real-time measurement of Ca2+ and force is essential to
Externí odkaz:
https://doaj.org/article/6d50eb6e3e1645eda58e373fd49ac088
Autor:
Jiaqi Wang, Chuchu Ma, Zhongyuan Tang, Zhengwu Sun, Eskandar Qaed, Xinming Chi, Jun Wang, Yazeed Jamalat, Zhaohong Geng, Zeyao Tang, Qiying Yao
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Oleanolic acid (3β-hydroxyolean-12-en-28-oic acid, OA) is a kind of pentacyclic triterpene, which widely distributes in nature. OA possesses a powerful anti-cancer effect; however, its low solubility limits its bioavailability and applicati
Externí odkaz:
https://doaj.org/article/b45c94b2b3fd4672bde239eb1cffcc14
Autor:
Mariana Shumliakivska, Guillermo Luxán, Inga Hemmerling, Marina Scheller, Xue Li, Carsten Müller-Tidow, Bianca Schuhmacher, Zhengwu Sun, Andreas Dendorfer, Alisa Debes, Simone-Franziska Glaser, Marion Muhly-Reinholz, Klara Kirschbaum, Jedrzej Hoffmann, Eike Nagel, Valentina O. Puntmann, Sebastian Cremer, Florian Leuschner, Wesley Tyler Abplanalp, David John, Andreas M. Zeiher, Stefanie Dimmeler
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Hematopoietic mutations in epigenetic regulators like DNA methyltransferase 3 alpha (DNMT3A), play a pivotal role in driving clonal hematopoiesis of indeterminate potential (CHIP), and are associated with unfavorable outcomes in patients suf
Externí odkaz:
https://doaj.org/article/20a09696ec974f6db501fff88d7fff78
Autor:
Fang Wang, Zhengwu Sun, Daoyong Peng, Shikha Gianchandani, Weidong Le, Johannes Boltze, Shen Li
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-22 (2023)
Abstract Background Cell-based strategies focusing on replacement or protection of dopaminergic neurons have been considered as a potential approach to treat Parkinson’s disease (PD) for decades. However, despite promising preclinical results, clin
Externí odkaz:
https://doaj.org/article/e088dd70917442f4ada1a43563030e78
Publikováno v:
Pharmaceutical Biology, Vol 59, Iss 1, Pp 1172-1180 (2021)
Context As a well-known traditional Chinese medicine for protecting the liver, the mechanism of Radix Gentianae (RG) remains unclear. Objective The hepatoprotective effect and metabonomics of RG were studied to explore the molecular and metabolic mec
Externí odkaz:
https://doaj.org/article/58fb414b8d9b45818d3e0ac7e0fec228
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-17 (2020)
Abstract Background It is not known what combination of bevacizumab and chemotherapy agents is the best therapeutic regimen. Comparative study results among the efficacies of bevacizumab plus chemotherapy remain controversial in patients with HER2-ne
Externí odkaz:
https://doaj.org/article/362b4b6076c4414e9456ce926d7f2804
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Ischemic stroke is a major cause of disability and mortality worldwide, but effective restorative treatments are very limited at present. Regenerative medicine research revealed that stem cells are promising therapeutic options. Dental pulp stem cell
Externí odkaz:
https://doaj.org/article/095006b6af8e4e1a98b82d1aff80c31b
Autor:
Zhongyuan Tang, Zonghui Zhang, Jiaqi Wang, Zhengwu Sun, Eskandar Qaed, Xinming Chi, Jun Wang, Yazeed Jamalat, Zhaohong Geng, Zeyao Tang, Qiying Yao
Phosphocreatine (PCr) has been shown to have a cardio-protective effect during cardiopulmonary resuscitation (CPR). However, little is known about its impact on atherosclerosis. In this study, we firstly evaluated the pharmacological effects of PCr o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22ff27d254abc2378419676e62e980a3
https://doi.org/10.21203/rs.3.rs-2969156/v1
https://doi.org/10.21203/rs.3.rs-2969156/v1
Publikováno v:
Pharmaceutical Biology
article-version (VoR) Version of Record
Pharmaceutical Biology, Vol 59, Iss 1, Pp 1172-1180 (2021)
article-version (VoR) Version of Record
Pharmaceutical Biology, Vol 59, Iss 1, Pp 1172-1180 (2021)
Context As a well-known traditional Chinese medicine for protecting the liver, the mechanism of Radix Gentianae (RG) remains unclear. Objective The hepatoprotective effect and metabonomics of RG were studied to explore the molecular and metabolic mec
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-17 (2020)
BMC Cancer
BMC Cancer
Background It is not known what combination of bevacizumab and chemotherapy agents is the best therapeutic regimen. Comparative study results among the efficacies of bevacizumab plus chemotherapy remain controversial in patients with HER2-negative me