Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Zhengtao Hu"'
Autor:
Zhengtao Hu, Tomas Ondrejcak, Pengpeng Yu, Yangyang Zhang, Yin Yang, Igor Klyubin, Sean P Kennelly, Michael J Rowan, Neng-Wei Hu
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 6, Pp 1213-1219 (2023)
Cognitive decline in Alzheimer’s disease correlates with the extent of tau pathology, in particular tau hyperphosphorylation that initially appears in the transentorhinal and related regions of the brain including the hippocampus. Recent evidence i
Externí odkaz:
https://doaj.org/article/0a9ffba41e18447cbef73f89a346a903
Autor:
Zhengtao Hu, Pengpeng Yu, Yangyang Zhang, Yin Yang, Manyi Zhu, Shuangying Qin, Ji-Tian Xu, Dongxiao Duan, Yong Wu, Deguo Wang, Michael J. Rowan, Neng-Wei Hu
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Soluble amyloid-β-protein (Aβ) oligomers, a major hallmark of AD, trigger the integrated stress response (ISR) via multiple pathologies including neuronal hyperactivation, microvascular hypoxia, and neuroinflammation. Increasing eIF2α pho
Externí odkaz:
https://doaj.org/article/800bf20ce0ae46ac9292771104346e06
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Background and ObjectivesSpinal cord stimulation can prevent myocardial ischemia and reperfusion arrhythmias, but the relevant neurons and mechanisms remain unknown. Thus, this study applied optogenetic techniques to selectively activate glutamatergi
Externí odkaz:
https://doaj.org/article/9e09158592de4d01a8312540992998b9
Autor:
Ruiming Zhu, Qian Bu, Dengqi Fu, Xue Shao, Linhong Jiang, Wei Guo, Bo Chen, Bin Liu, Zhengtao Hu, Jingwei Tian, Yinglan Zhao, Xiaobo Cen
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-11 (2018)
Abstract Background The nucleus accumbens in the midbrain dopamine limbic system plays a key role in cocaine addiction. Toll-like receptors (TLRs) are important pattern-recognition receptors (PPRs) in the innate immune system that are also involved i
Externí odkaz:
https://doaj.org/article/85bd2c9e9c514755b4494cf0dd7aad85
Autor:
Hongyu Li, Qian Bu, Bo Chen, Xue Shao, Zhengtao Hu, Pengchi Deng, Lei Lv, Yi Deng, Ruiming Zhu, Yan Li, Baolai Zhang, Jing Hou, Changman Du, Qian Zhao, Dengqi Fu, Yinglan Zhao, Xiaobo Cen
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87040 (2014)
Nicotine, one of the most commonly used drugs, has become a major concern because tobacco serves as a gateway drug and is linked to illicit drug abuse, such as cocaine and marijuana. However, previous studies mainly focused on certain genes or neurot
Externí odkaz:
https://doaj.org/article/7da286fe40b045ce8e162c70307d97ad
Publikováno v:
IEEE Transactions on Automation Science and Engineering. :1-19
This paper presented an regrasp planning method to eliminate grasp uncertainty while considering the geometric constraints of a fixture. The method automatically finds the Stable Placement Poses (SPPs) of an object on a Triangular Corner Fixture (TCF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52a3d1107cfe52877048298a89b745d1
https://doi.org/10.1109/tase.2023.3234047
https://doi.org/10.1109/tase.2023.3234047
Autor:
Yangyang, Zhang, Yin, Yang, Zhengtao, Hu, Manyi, Zhu, Shuangying, Qin, Pengpeng, Yu, Bo, Li, Jitian, Xu, Tomas, Ondrejcak, Igor, Klyubin, Michael J, Rowan, Neng-Wei, Hu
Publikováno v:
Journal of Alzheimer's Disease. 89:335-350
Background: Cognitive decline in Alzheimer’s disease (AD) correlates with the extent of tau pathology, in particular tau hyperphosphorylation, which is strongly age-associated. Although elevation of cerebrospinal fluid or blood levels of phosphoryl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca018623833782f9ebc426179af0644
https://doi.org/10.3233/jad-220351
https://doi.org/10.3233/jad-220351
Publikováno v:
IEEE Transactions on Robotics. 38:1139-1159
This article develops a mechanical screwing tool and its manipulation policies for two-finger parallel robotic grippers. The tool is based on a combined scissor-like element (SLE) and double-ratchet mechanism that converts the gripping motion of two-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8b1778d7ef245eb6a08e74411b000b2
https://doi.org/10.1109/tro.2021.3091282
https://doi.org/10.1109/tro.2021.3091282
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 378:197-206
Phosphorylation of the eukaryotic translation initiation factor 2 α-subunit (eIF2ɑ)，which subsequently upregulates activating transcription factor 4 (ATF4), is the core event in the integrated stress response (ISR) pathway. Previous studies indic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44680e63b63c3fe0d540290d75b8f8ca
https://doi.org/10.1124/jpet.121.000491
https://doi.org/10.1124/jpet.121.000491
Autor:
Yangyang Zhang, Yin Yang, Zhengtao Hu, Manyi Zhu, Shuangying Qin, Pengpeng Yu, Bo Li, Jitian Xu, Michael J. Rowan, Neng-Wei Hu
The progressive cognitive decline in Alzheimer’s disease (AD) patients correlates with the extent of tau pathology, in particular tau hyperphosphorylation, which is strongly age-associated. Although elevation of phosphorylated tau (p-Tau) on residu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::684f68e4afd334effd40c787081bb967
https://doi.org/10.1101/2022.03.28.486022
https://doi.org/10.1101/2022.03.28.486022
