Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Zhengtao Chen"'
Publikováno v:
Renal Failure, Vol 46, Iss 2 (2024)
Various factors, both internal and external, can disrupt endoplasmic reticulum (ER) homeostasis and increase the burden of protein folding, resulting in ER stress. While short periods of ER stress can help cells return to normal function, excessive o
Externí odkaz:
https://doaj.org/article/d8f035e8f64b4b5f8dccad6b6096d1dc
Autor:
Qingzhi Liang, Xiaoqin Liu, Xi Peng, Ting Luo, Yi Su, Xin Xu, Hongyan Xie, Hong Gao, Zhengtao Chen, Chunguang Xie
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Fibrosis is a public health issue of great concern characterized by the excessive deposition of extracellular matrix, leading to the destruction of parenchymal tissue and organ dysfunction that places a heavy burden on the global healthcare system du
Externí odkaz:
https://doaj.org/article/f50dfb79182243898eaac73d17e9cf97
Autor:
Lianjun Ao, Zhengtao Chen, Jiacheng Yin, Yulin Leng, Yue Luo, Xiaoxu Fu, Hanyu Liu, Xiaoke Liu, Hong Gao, Chunguang Xie
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Abstract Background: Diabetic cardiomyopathy (DCM) is one of the serious microvascular complications of diabetes mellitus. It is often associated with clinical manifestations such as arrhythmias and heart failure, and significantly reduces the qualit
Externí odkaz:
https://doaj.org/article/825da323534548348a7d89818a6e4126
Autor:
Zehua Zhang, Yulin Leng, Zhengtao Chen, Xiaoxu Fu, Qingzhi Liang, Xi Peng, Hongyan Xie, Hong Gao, Chunguang Xie
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Type 2 diabetes mellitus (T2DM) is a clinical metabolic syndrome characterized by persistent hyperglycemia. Patients with T2DM are more likely to have carotid atherosclerosis (CAS), which can lead to dizziness, amaurosis or even stroke. C
Externí odkaz:
https://doaj.org/article/658e40ce91574eb78347924fe1cbfc73
Autor:
Xueru Wang, Gang Xu, Hanyu Liu, Zhengtao Chen, Susu Huang, Jiushu Yuan, Chunguang Xie, Lian Du
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 157, Iss , Pp 114059- (2023)
Diabetic peripheral neuropathy (DPN) is a common complication of diabetes. Glycemic control and lifestyle alterations cannot prevent the development of DPN; therefore, investigating effective treatments for DPN is crucial. Schwann cells (SCs) maintai
Externí odkaz:
https://doaj.org/article/b4f89a75ffee40a1bc036683954ad772
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Obesity–insulin resistance–β-cells apoptosis” is an important trilogy of the pathogenesis of type 2 diabetes. With the global pandemic of obesity and diabetes, continuous research and development of new drugs focuses on the prevention of the p
Externí odkaz:
https://doaj.org/article/11661db30ea24d72afd116c50f2e7a20
Autor:
Zhengtao Chen, Haoyue Feng, Chuan Peng, Zehua Zhang, Qianghua Yuan, Hong Gao, Shiyun Tang, Chunguang Xie
Publikováno v:
Molecules, Vol 28, Iss 4, p 1990 (2023)
The kidney is an important organ in the human body, with functions such as urine production, the excretion of metabolic waste, the regulation of water, electrolyte and acid–base balance and endocrine release. The morbidity and mortality of kidney d
Externí odkaz:
https://doaj.org/article/c90d6ec59f15468aa14af2f5eeac9b35
Autor:
Fengxia Lin, Xiaojing Huang, Fuya Xing, Luhua Xu, Weiwei Zhang, Zhengtao Chen, Xiao Ke, Yinzhi Song, Zhicong Zeng
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 129, Iss , Pp 110400- (2020)
Background: This study aimed to evaluate the role of Semen Brassicae, a common Traditional Chinese Medicine, in the treatment of hypertension. Methods: Spontaneously hypertensive rats (SHRs) were divided into five groups and were gavaged with either
Externí odkaz:
https://doaj.org/article/810fbad88c4a4aeba273919d96cb2f36
Autor:
Yirong Ma, Junyu Lai, Zhengtao Chen, Qiang Wan, Xianlin Shi, Hao Zhou, Jiaming Li, Zurong Yang, Jianguang Wu
Publikováno v:
Medicine; 8/2/2024, Vol. 103 Issue 31, p1-12, 12p
Autor:
Shanlong, Zhang, Li, Kang, Xiaoxue, Dai, Junlan, Chen, Zhengtao, Chen, Meixiang, Wang, Huantong, Jiang, Xin, Wang, Suqin, Bu, Xinyuan, Liu, Guohui, Zhang, Hua, Tang
Publikováno v:
Free Radical Biology and Medicine. 193:202-212
Ferroptosis is a novel form of regulated cell death characterized by the iron-dependent accumulation of lipid peroxides to lethal levels, which is morphologically, biochemically, and genetically distinct from apoptosis, necroptosis, autophagy, and py