Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Zhengtao, Gu"'
Publikováno v:
PeerJ, Vol 11, p e16590 (2023)
Background: The pathological mechanism of heat stroke (HS) involves the acute phase response, unbalanced immunological/inflammatory reactions, and coagulation initiation, especially platelet activation. Although exosomes contain proteins involved in
Externí odkaz:
https://doaj.org/article/bc5bd0d41d31429b8078f69ccd1ac0bb
Publikováno v:
Heliyon, Vol 9, Iss 12, Pp e22805- (2023)
Aim: To investigate the mechanism of p53-mediated suppression of heat stress-induced oxidative stress damage by manganese superoxide dismutase (MnSOD) in endothelial cells (ECs). Methods: Primary ECs isolated from mouse aortas were used to examine th
Externí odkaz:
https://doaj.org/article/8d40bf7e9bf5483d859f79aad13a1f42
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-12 (2022)
Abstract Background Traumatic hemorrhagic shock (THS) is the main cause of death in trauma patients with high mortality. Rapid control of the source of bleeding and early resuscitation are crucial to clinical treatment. Guidelines recommend isotonic
Externí odkaz:
https://doaj.org/article/d003eb57f359432dabf73772e826cc28
Autor:
Zhimin Zou, Li Li, Qin Li, Peng Zhao, Kun Zhang, Chengyong Liu, Daozhang Cai, Marc Maegele, Zhengtao Gu, Qiaobing Huang
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-21 (2022)
Abstract Background Traumatic brain injury (TBI) remains one of the main causes for disability and death worldwide. While the primary mechanical injury cannot be avoided, the prevention of secondary injury is the focus of TBI research. Present study
Externí odkaz:
https://doaj.org/article/1225b629dda6473a9faccd818b157be8
Autor:
Wei Xia, Jing Xie, Zhiqing Cai, Xuhua Liu, Jing Wen, Zhong-Kai Cui, Run Zhao, Xiaomei Zhou, Jiahui Chen, Xinru Mao, Zhengtao Gu, Zhimin Zou, Zhipeng Zou, Yue Zhang, Ming Zhao, Maegele Mac, Qiancheng Song, Xiaochun Bai
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Concomitant traumatic brain injury accelerates bone healing, but the mechanism is unclear. Here, the authors show that injured neurons, mainly those in the hippocampus, release osteogenic miRNA-enriched small extracellular vesicles, which targete ost
Externí odkaz:
https://doaj.org/article/ed80d699848c4bf1a25705f933ee0561
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-16 (2021)
Abstract Traumatic brain injury (TBI) remains one of the leading causes of death and disability worldwide; more than 10 million people are hospitalized for TBI every year around the globe. While the primary injury remains unavoidable and not accessib
Externí odkaz:
https://doaj.org/article/c75493d1cde14b7d9d4b9af5645388af
Preventing necroptosis by scavenging ROS production alleviates heat stress-induced intestinal injury
Autor:
Li Li, Hongping Tan, Zhimin Zou, Jian Gong, Junjie Zhou, Na Peng, Lei Su, Marc Maegele, Daozhang Cai, Zhengtao Gu
Publikováno v:
International Journal of Hyperthermia, Vol 37, Iss 1, Pp 517-530 (2020)
Background Worldwide heat stroke incidence has increased in recent years and is associated with high morbidity and mortality. Therefore, it is critical to identify mechanisms that mediate heat stroke. Previous studies suggested that damage to the sma
Externí odkaz:
https://doaj.org/article/4929bba4fda14ce488fad5014aadac70
Autor:
Qin Li, Peng Zhao, Yu Wen, Zhimin Zou, Xihe Qin, Hongping Tan, Jian Gong, Qihua Wu, Chen Zheng, Kun Zhang, Qiaobing Huang, Marc Maegele, Zhengtao Gu, Li Li
Publikováno v:
Shock. 59:460-468
Autor:
Ziyun Shao, Yongwen Feng, Li Zhong, Qifeng Xie, Ming Lei, Zheying Liu, Conglin Wang, Jingjing Ji, Huiheng Liu, Zhengtao Gu, Zhongwei Hu, Lei Su, Ming Wu, Zhifeng Liu
Publikováno v:
Clinical & Translational Immunology, Vol 9, Iss 10, Pp n/a-n/a (2020)
Abstract Objective Coronavirus disease 2019 (COVID‐19) outbreak is a major challenge all over the world, without acknowledged treatment. Intravenous immunoglobulin (IVIG) has been recommended to treat critical coronavirus disease 2019 (COVID‐19)
Externí odkaz:
https://doaj.org/article/373f944ca81149b2bdc4a7b415d3d76b
Autor:
Qin, Li, Peng, Zhao, Yu, Wen, Zhimin, Zou, Xihe, Qin, Hongping, Tan, Jian, Gong, Qihua, Wu, Chen, Zheng, Kun, Zhang, Qiaobing, Huang, Marc, Maegele, Zhengtao, Gu, Li, Li
Publikováno v:
Shock (Augusta, Ga.).
Traumatic brain injury (TBI) is a kind of disease with high morbidity, mortality and disability, and its pathogenesis is still unclear. Research shows that nucleotide-binding oligomerization domain-like receptor containing pyrin domain 3 (NLRP3) acti