Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Zhengtai Chen"'
Autor:
Zhengtai Chen, Hongqiang Wu, Jianxin Yang, Baolong Li, Jian Ding, Sheng Cheng, Nageeb Bsoul, Chenxi Zhang, jiaorong li, Haixiao Liu, Damu Lin, Weiyang Gao
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Melatonin induces Parkin 1 dependent mitophagy in human umbilical vein endothelial cells through the AMPK/TFEB pathway, alleviating oxidative stress and apoptosis, which also enables skin flap survival in vivo.
Externí odkaz:
https://doaj.org/article/f73ccf6d13be416fa3ff2c376335aefa
Autor:
Haiwei Ma, Chenglong Xie, Zhengtai Chen, Gaolu He, Zihan Dai, Hanchen Cai, Haojie Zhang, Hongwei Lu, Hongqiang Wu, Xinli Hu, Kailiang Zhou, Gang Zheng, Huazi Xu, Cong Xu
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-15 (2022)
Abstract Intervertebral disc degeneration (IVDD) is a chronic age-related degenerative disease accompanied by complex pathophysiological mechanisms. Increasing evidence indicates that NLRP3 inflammasome mediated pyroptosis of nucleus pulposus (NP) ce
Externí odkaz:
https://doaj.org/article/0be47c42b98b4b17bc6fb31c9710fc62
Autor:
Baolong Li, Zhengtai Chen, Xiaobin Luo, Chenxi Zhang, Hongyu Chen, Shuxuan Wang, Mengyao Zhao, Haiwei Ma, Junling Liu, Mengshi Cheng, Yanyan Yang, Hede Yan
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Multiterritory perforator flap is an important plastic surgery technique, yet its efficacy can be limited by partial necrosis at the choke Ⅱ zone. Butylphthalide (NBP) has been used for many diseases but has not been studied in the multiterritory p
Externí odkaz:
https://doaj.org/article/c46ea431171a4cafbc856dbe887b75c6
Autor:
Zhengtai Chen, Chenxi Zhang, Haiwei Ma, Zihuai Huang, Jiafeng Li, Junshen Lou, Baolong Li, Qi Tu, Weiyang Gao
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Multiterritory perforator flap survival is commonly applied in surgical tissue reconstructions and covering of large skin defects. However, multiple risk factors such as ischemia, reperfusion injury, and apoptosis after reconstructive surgeries cause
Externí odkaz:
https://doaj.org/article/188618ef134e4c2b8e0d1c8d665a6e54
Autor:
Haiwei Ma, Chenglong Xie, Gaolu He, Zhengtai Chen, Hongwei Lu, Hongqiang Wu, Hancheng Cai, Zihan Dai, Baolong Li, Cong Xu, Enxing Xue
Publikováno v:
Journal of Cellular and Molecular Medicine. 26:725-735
Abnormal lipid metabolism, such as systemic increased free fatty acid, results in overproduction of pro-inflammatory enzymes and cytokines, which is crucial in the development of obesity-related osteoarthritis (OA). However, there are only a few drug
Autor:
Baolong Li, Zhe Zhang, Hui Wang, Dupiao Zhang, Tao Han, Hongyu Chen, Jianpeng Chen, Zhengtai Chen, Yutong Xie, Liang Wang, Najeeb Bsoul, Xijie Zhou, Hede Yan
Publikováno v:
Free radical biologymedicine. 185
Schwann cells (SCs) are the major glial cells in peripheral nervous system. They unsheathe and myelinate axons and play an essential role in peripheral nerve regeneration. Several studies report that Parkin-mediated mitophagy is associated with vario
Autor:
Zhengtai Chen, Hongqiang Wu, Jianxin Yang, Baolong Li, Jian Ding, Sheng Cheng, Nageeb Bsoul, Chenxi Zhang, jiaorong li, Haixiao Liu, Damu Lin, Weiyang Gao
Publikováno v:
Communications biology. 5(1)
The random-pattern skin flap is a crucial technique in reconstructive surgery and flap necrosis caused by ischemia/reperfusion injury is a major postoperative complication. Herein, we investigated the mechanism of mitophagy induced by Melatonin (ML)
Autor:
Baolong Li, Cong Xu, Jiaoxiang Chen, Chenxi Zhang, Zhengtai Chen, Xiao-Fen Hu, Najeeb Bsoul, Zhenxuan Shao, Weiyang Gao, Renhao Jiang
Publikováno v:
International Immunopharmacology. 89:107079
Osteoarthritis (OA) is a progressive and degenerative joint disease. Aloin is a bitter and yellow-brown-coloured compound from the Aloe plant and is allowed for use in foods as a “natural flavour”. In our study, we examined the protective effects