Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Zhengrui You"'
Autor:
You Li, Zhiqiang Li, Ruiling Chen, Min Lian, Hanxiao Wang, Yiran Wei, Zhengrui You, Jun Zhang, Bo Li, Yikang Li, Bingyuan Huang, Yong Chen, Qiaoyan Liu, Zhuwan Lyu, Xueying Liang, Qi Miao, Xiao Xiao, Qixia Wang, Jingyuan Fang, YongYong Shi, Xiangdong Liu, Michael F. Seldin, M. Eric Gershwin, Ruqi Tang, Xiong Ma
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Primary biliary cholangitis is a rare, chronic immune-mediated liver disease triggered by environmental exposures in genetically susceptible individuals. Here, the authors investigate the functional mechanism underlying the association of 19p13.3 var
Externí odkaz:
https://doaj.org/article/c3bffe3f09684055a2d88786709182d8
Autor:
Yong Chen, Xiangwei Hua, Bingyuan Huang, Stella Karsten, Zhengrui You, Bo Li, You Li, Yikang Li, Jubo Liang, Jun Zhang, Yiran Wei, Ruiling Chen, Zhuwan Lyu, Xiao Xiao, Min Lian, Jue Wei, Jingyuan Fang, Qi Miao, Qixia Wang, Ulrika Warpman Berglung, Ruqi Tang, Thomas Helleday, Xiong Ma
Publikováno v:
Hepatology Communications, Vol 6, Iss 5, Pp 1016-1031 (2022)
Autoimmune hepatitis (AIH) is an inflammatory liver disease driven by the hyperactivation of various intrahepatic antigen‐specific T cells due to a breach of immune tolerance. Studies in immunometabolism demonstrate that activated T cells harbor in
Externí odkaz:
https://doaj.org/article/2d8f714164314a3ebac9af9b639b9dbc
Autor:
Changjie Yang, Qiwei Qian, Yudong Zhao, Bingyuan Huang, Ruilin Chen, Qiyu Gong, Hao Ji, Chenchen Wang, Lei Xia, Zhengrui You, Jianjun Zhang, Xiaosong Chen
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Background and aimsThe key role of tissue-resident memory T (TRM) cells in the immune regulation of hepatocellular carcinoma (HCC) has been investigated and reported, but the regulatory mechanism of tumor microenvironment on TRM cells is still unclea
Externí odkaz:
https://doaj.org/article/98e2688f9d5b4a45829e2784632b24c1
Autor:
Yiyan Ou, Ruiling Chen, Qiwei Qian, Nana Cui, Qi Miao, Ruqi Tang, Zhengrui You, Xiong Ma, Qixia Wang
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Background and aimsTetraspanin proteins are closely related to the functional changes of B cells, including antigen presentation, production of cytokines, and transduction. We aim to explore the potential role of Tetraspanin 1 (TSPAN1) in the biologi
Externí odkaz:
https://doaj.org/article/1932eb88ac8348049b3a53a178de0a0a
Autor:
Yudong Zhao, Wei He, Chenchen Wang, Nana Cui, Changjie Yang, Zhengrui You, Bisheng Shi, Lei Xia, Xiaosong Chen
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Background and objectivesAcute on chronic liver failure (ACLF) is characterized by the immunologic dissonance during the prolonged pathogenic development. Both abnormal innate immune response and adaptive T-cell response have been reported in patient
Externí odkaz:
https://doaj.org/article/abbf8010612a4c39bba636ff35a5d36f
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Tissue-resident memory (TRM) T cells are a unique subset of memory T cells that are critical for the first line of defense against pathogens or antigens in peripheral non-lymphoid tissues such as liver, gut, and skin. Generally, TRM cells are well ad
Externí odkaz:
https://doaj.org/article/100b74cffe624bd5b820f29f68fcd211
Autor:
Qiwei Qian, Nana Cui, Bingyuan Huang, Yudong Zhao, Qiaoyan Liu, Mingli Hu, Bo Li, Qixia Wang, Qi Miao, Zhengrui You, Xiong Ma, Ruqi Tang
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Background and objectivesAutoimmune hepatitis (AIH) is characterized by the expansion and accumulation of pathogenic T cells in liver. Although CD6 and its ligand activated leukocyte cell adhesion molecule (ALCAM) are involved in the evolution of mul
Externí odkaz:
https://doaj.org/article/62096c7da21243f1a9a41722629b0dcb
Autor:
Bo Li, Jun Zhang, Yong Chen, Qixia Wang, Li Yan, Rui Wang, Yiran Wei, Zhengrui You, Yikang Li, Qi Miao, Xiao Xiao, Min Lian, Weihua Chen, Dekai Qiu, Jingyuan Fang, M. Eric Gershwin, Ruqi Tang, Xiong Ma
Publikováno v:
Gut Microbes, Vol 13, Iss 1 (2021)
Background: Increasing data suggests an interaction between bile acids and intestinal microbiota in the pathogenesis of primary biliary cholangitis (PBC). Bile acid sequestrants are widely used to bind bile acids in the intestinal lumen and are there
Externí odkaz:
https://doaj.org/article/e1c0c45acbbc40dc916bc2a966f68bbd
Autor:
Zhaolian Bian, Yanshen Peng, Zhengrui You, Qixia Wang, Qi Miao, Yuan Liu, Xiaofeng Han, Dekai Qiu, Zhiping Li, Xiong Ma
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 1, Pp 44-54 (2013)
Our objective was to investigate the potential roles of CCN1 in the inflammation and macrophage infiltration of nonalcoholic fatty liver disease (NAFLD). The regulation of hepatic CCN1 expression was investigated in vitro with murine primary hepatocy
Externí odkaz:
https://doaj.org/article/a16454737604457c98a2e5bd71cf4a66
Autor:
Li Zhao, Yanli Tang, Zhengrui You, Qixia Wang, Shuwen Liang, Xiaofeng Han, Dekai Qiu, Jue Wei, Yuan Liu, Lei Shen, Xiaoyu Chen, Yanshen Peng, Zhiping Li, Xiong Ma
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18909 (2011)
T helper cells that produce IL-17 (Th17 cells) have recently been identified as the third distinct subset of effector T cells. Emerging data suggests that Th17 cells play an important role in the pathogenesis of many liver diseases by regulating inna
Externí odkaz:
https://doaj.org/article/18b6e9f384794243bd57c3072d3ee346