Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Zhengrong Zhangding"'
Autor:
Jinchun Wu, Yang Liu, Liqiong Ou, Tingting Gan, Zhengrong Zhangding, Shaopeng Yuan, Xinyi Liu, Mengzhu Liu, Jiasheng Li, Jianhang Yin, Changchang Xin, Ye Tian, Jiazhi Hu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Mitochondria serve as the cellular powerhouse, and their distinct DNA makes them a prospective target for gene editing to treat genetic disorders. However, the impact of genome editing on mitochondrial DNA (mtDNA) stability remains a mystery
Externí odkaz:
https://doaj.org/article/381b32eb86f24fcf9a522190b64ea5c1
Autor:
Yang Liu1,2, Zhengrong Zhangding3, Xuhao Liu3, Tingting Gan4,5,6, Chen Ai1,6, Jinchun Wu5,7, Haoxin Liang7, Chen, Mohan7, Yuefeng Guo7, Rusen Lu7, Yongpeng Jiang1,6, Xiong Ji1,6, Ning Gao5,8, Daochun Kong5,9, Qing Li1,10, Jiazhi Hu5,7,11 hujz@pku.edu.cn
Publikováno v:
Science. 3/15/2024, Vol. 383 Issue 6688, p1215-1222. 8p. 5 Diagrams.
Publikováno v:
Nucleic acids research. 50(19)
CRISPR/Cas9 has been adapted to disrupt endogenous genes in adoptive T-lymphocyte therapy to prevent graft-versus-host disease. However, genome editing also generates prevalent deleterious structural variations (SVs), including chromosomal translocat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1af506f65c63a96c57e27454300d8da
https://pubmed.ncbi.nlm.nih.gov/36243978
https://pubmed.ncbi.nlm.nih.gov/36243978
Autor:
Jinchun Wu, Yang Liu, Zhengrong Zhangding, Xuhao Liu, Chen Ai, Tingting Gan, Yiyang Liu, Jianhang Yin, Weiwei Zhang, Jiazhi Hu
Cohesin participates in loop formation by extruding DNA fibers from its ring-shaped structure. Cohesin dysfunction eliminates chromatin loops but only causes modest transcription perturbation, which cannot fully explain the frequently observed mutati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f39060adb5da6a33f1b6c0655c055f1
https://doi.org/10.1101/2021.12.06.471507
https://doi.org/10.1101/2021.12.06.471507
