Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Zhengquan Huang"'
Publikováno v:
Experimental Gerontology, Vol 190, Iss , Pp 112413- (2024)
Background: Osteoporotic osteoarthritis (OP-OA) is a severe pathological form of OA, urgently requiring precise management strategies and more efficient interventions. Emodin (Emo), an effective ingredient found in the traditional Chinese medicine rh
Externí odkaz:
https://doaj.org/article/1751c712695f4b3d8515f115133a76da
Autor:
Laigen Zhang, Xiaoqing Shi, Zhengquan Huang, Jun Mao, Wei Mei, Liang Ding, Li Zhang, Runlin Xing, Peimin Wang
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background This study used a network pharmacology approach to elucidate the molecular mechanism governing the effect of Radix Achyranthis Bidentatae (RAB) on osteoarthritis (OA). Methods Based on oral bioavailability and drug-likeness, the m
Externí odkaz:
https://doaj.org/article/6fa29ba67fa14562876e9afb7c49291b
Autor:
Peng Wu, Zhengquan Huang, Jinjun Shan, Zichen Luo, Nongshan Zhang, Songjiang Yin, Cunsi Shen, Runlin Xing, Wei Mei, Yancheng Xiao, Bo Xu, Jun Mao, Peimin Wang
Publikováno v:
Chinese Medicine, Vol 15, Iss 1, Pp 1-13 (2020)
Abstract Background Our previous clinical evidence suggested that the direct application of “Sanse powder” the main ingredient of “Yiceng” might represent an alternative treatment for knee osteoarthritis. However, the mechanism underlying its
Externí odkaz:
https://doaj.org/article/c0d1d6a97cfa43ac96531e7418da5d27
Autor:
Xiaoqing Shi, Hao Liu, Runlin Xing, Wei Mei, Li Zhang, Liang Ding, Zhengquan Huang, Peimin Wang
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 14, Iss 1, Pp 1-11 (2019)
Abstract Background To evaluate the effect of intramedullary nail and locking plate in the treatment of proximal humerus fracture (PHF). Methods China National Knowledge Infrastructure (CNKI), Chinese Scientific Journals Database (VIP), Wan-fang data
Externí odkaz:
https://doaj.org/article/daa5f38bf8a845da909a94e3cd4f5dc4
Autor:
Songjiang Yin, Li Zhang, Liang Ding, Zhengquan Huang, Bo Xu, XiaoChen Li, Peimin Wang, Jun Mao
Publikováno v:
Journal of Inflammation, Vol 15, Iss 1, Pp 1-9 (2018)
Abstract Background Chondrocyte apoptosis is a central feature in the progression of osteoarthritis (OA), and would be triggered by sustained elevation of intracellular calcium ion (Ca2+), also known as a cellular second messenger. Transient receptor
Externí odkaz:
https://doaj.org/article/664dc6f5515845cf92dfb7a5ee25910a
Autor:
Li Zhang, Runlin Xing, Zhengquan Huang, Liang Ding, Mingchao Li, Xiaochen Li, Peimin Wang, Jun Mao
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Bone changes have always been the focus of research on osteoarthritis, but the number of studies on synovitis has increased only over the last 10 years. Our current understanding is that the mechanism of osteoarthritis involves all the tissues that m
Externí odkaz:
https://doaj.org/article/20d7edfa0bd14445946e273025f52dd7
Autor:
Zhenyuan Ma, Zhengquan Huang, Li Zhang, Xiaochen Li, Bo Xu, Yancheng Xiao, Xiaoqing Shi, Haosheng Zhang, Taiyang Liao, Peimin Wang
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Objectives: Synovitis plays an important role in knee osteoarthritis (KOA) pain. The activation of the NOD-like receptor protein 3 (NLRP3) inflammasome in fibroblast-like synoviocytes (FLSs) promotes KOA development. In this study, we aimed to invest
Externí odkaz:
https://doaj.org/article/1bd3d57b19834c98baa4e3bd388426b7
Autor:
Li Zhang, Xiaochen Li, Haosheng Zhang, Zhengquan Huang, Nongshan Zhang, Runlin Xing, Peimin Wang
Publikováno v:
Mediators of Inflammation, Vol 2021 (2021)
Increasing evidence has shown that NLRP3 inflammasome activation participates in chronic aseptic inflammation and is related to tissue fibrosis. Our last study also revealed the vital role of NLRP3 inflammasome, highly associated with tissue hypoxia,
Externí odkaz:
https://doaj.org/article/c74a2fdc5f5745779a7cbb10fe796a41
Publikováno v:
Mediators of Inflammation, Vol 2019 (2019)
Increasing evidence has shown that macrophage pyroptosis in different tissues participates in chronic aseptic inflammation and is related to tissue fibrosis. Our last studies also revealed the vital role of synovial fibroblast pyroptosis in the onset
Externí odkaz:
https://doaj.org/article/46471a94fdc641c6bfc306addc431901
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26ca470832904a94268a2cce040602cf
https://doi.org/10.1007/s11626-023-00769-z
https://doi.org/10.1007/s11626-023-00769-z