Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Zhengqing He"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundAmyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, which leads to muscle weakness and eventual paralysis. Numerous studies have indicated that mitophagy and immune inflammation have a significant impact on the onset a
Externí odkaz:
https://doaj.org/article/49cb293a65884bf6b792d9369bcb1897
Autor:
Feng Feng, Hongfen Wang, Jiajin Liu, Zhanjun Wang, Baixuan Xu, Kun Zhao, Xiaoyong Tao, Zhengqing He, Fei Yang, Xusheng Huang
Publikováno v:
Brain and Behavior, Vol 11, Iss 8, Pp n/a-n/a (2021)
Abstract Objectives To investigate the genetic and clinical features of Chinese sporadic amyotrophic lateral sclerosis (SALS) patients with TARDBP mutations, we carried out a genetic analysis in a cohort of 391 SALS patients and explored the clinical
Externí odkaz:
https://doaj.org/article/e02f5c4a8401442b95976dff76a339d4
Publikováno v:
Chinese Medical Journal, Vol 135, Iss 4, Pp 480-481 (2022)
Externí odkaz:
https://doaj.org/article/8c984b6f575243a598b047eecdadca21
Autor:
Yanran Li, Bo Sun, Zhanjun Wang, Zhengqing He, Fei Yang, Hongfen Wang, Fang Cui, Zhaohui Chen, Li Ling, Chaodong Wang, Xusheng Huang
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Amyotrophic lateral sclerosis (ALS) is a fatal progressive neurodegenerative disease involving the upper and lower motor neurons of the spinal cord, brainstem, and cerebral cortex. At least 30 genes have been implicated in familial ALS (fALS) and spo
Externí odkaz:
https://doaj.org/article/9e6ab379c02043639c75583440d2a942
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 27, Iss 1, p 001 (2022)
Background: Endoplasmic reticulum stress (ERS) occurred in S63del mutant CMT1B mice model, and few drugs has been studied. Mesencephalic astrocyte-derived neurotrophic factor (MANF) can inhibit ERS. This study aimed at investigating the effect of MAN
Externí odkaz:
https://doaj.org/article/ce57546c96544d2daacbf92fb2b5ef61
Publikováno v:
Neurological Sciences. 44:897-903
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37bb53a010b61a00e2947f8f7e44e122
https://doi.org/10.1007/s10072-022-06494-x
https://doi.org/10.1007/s10072-022-06494-x
Autor:
Bo Sun, Haoran Wang, Feng Feng, Fei Yang, Fang Cui, Zhengqing He, Hongfen Wang, Xusheng Huang, Jiongming Bai
Publikováno v:
Neurological Sciences. 43:1817-1822
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease. Spreading pattern and time interval of spreading are getting more and more attention. The aim of present study was to investigate spreading pattern in bulbar onset ALS patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4207466df2d48a03d2f542ffedef46b
https://doi.org/10.1007/s10072-021-05556-w
https://doi.org/10.1007/s10072-021-05556-w
Autor:
Zhengqing He, Xinyuan Pang, Jiongming Bai, Haoran Wang, Feng Feng, Rongrong Du, Xusheng Huang
Publikováno v:
Neurocase. 28(3)
To analyze the clinical, imaging, and genetic characteristics of a patient diagnosed with adult-onset Krabbe disease (KD). Clinical and imaging features of the patient were retrospectively reviewed. The patient, a 40-year-old female, presented adult-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b638eae9c4816b1e677dad9a5eecaba3
https://pubmed.ncbi.nlm.nih.gov/35654103
https://pubmed.ncbi.nlm.nih.gov/35654103
Autor:
Zhengqing He, Fang Cui, Yanran Li, Fei Yang, Jiongming Bai, Haoran Wang, Bo Sun, Xusheng Huang, Hongfen Wang
Publikováno v:
Acta Neurologica Belgica. 122:1169-1175
Mutations in the SH3TC2 gene cause Charcot–Marie–Tooth disease type 4C (CMT4C), characterized by inherited demyelinating peripheral neuropathy. CMT4C is a common form of CMT4/autosomal recessive (AR) CMT1. This study examined the SH3TC2 variants,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08f90b53e110e675881c089b9d8beb13
https://doi.org/10.1007/s13760-021-01605-5
https://doi.org/10.1007/s13760-021-01605-5
Publikováno v:
ACS applied bio materials. 3(8)
Rapid and sensitive detection of nucleic acids is vital for disease diagnosis. This work designed an enzyme-free isothermal strategy for rapid exponential signal amplification through target-triggered catalytic hairpin assembly (CHA) to induce the sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c806de72575cf7274e559c5e40bcce5
https://pubmed.ncbi.nlm.nih.gov/35021708
https://pubmed.ncbi.nlm.nih.gov/35021708