Zobrazeno 1 - 10
of 577
pro vyhledávání: '"Zhengping Zhuang"'
Autor:
Muyuan You, Minjie Fu, Zhewei Shen, Yuan Feng, Licheng Zhang, Xianmin Zhu, Zhengping Zhuang, Ying Mao, Wei Hua
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTBrain metastasis is the most devasting form of lung cancer. Recent studies highlight significant differences in the tumor microenvironment (TME) between lung cancer brain metastasis (LCBM) and primary lung cancer, which contribute significant
Externí odkaz:
https://doaj.org/article/1aabdee1ffb34512ae1b102ab1503aee
Autor:
Herui Wang, Rogelio Medina, Juan Ye, Yaping Zhang, Samik Chakraborty, Alex Valenzuela, Ondrej Uher, Katerina Hadrava Vanova, Mitchell Sun, Xueyu Sang, Deric M. Park, Jan Zenka, Mark R. Gilbert, Karel Pacak, Zhengping Zhuang
Publikováno v:
Advanced Science, Vol 11, Iss 14, Pp n/a-n/a (2024)
Abstract Despite strides in immunotherapy, glioblastoma multiforme (GBM) remains challenging due to low inherent immunogenicity and suppressive tumor microenvironment. Converting “cold” GBMs to “hot” is crucial for immune activation and impro
Externí odkaz:
https://doaj.org/article/402be77c1897447c8a899980d3ead908
Autor:
Feiqiong Gao, Qigu Yao, Jiaqi Zhu, Wenyi Chen, Xudong Feng, Bing Feng, Jian Wu, Karel Pacak, Jared Rosenblum, Jiong Yu, Zhengping Zhuang, Hongcui Cao, Lanjuan Li
Publikováno v:
Pharmacological Research, Vol 202, Iss , Pp 107135- (2024)
Externí odkaz:
https://doaj.org/article/b0437a71e28744fb90f180ab576558f6
Autor:
Juan Ye, Herui Wang, Rogelio Medina, Samik Chakraborty, Mitchell Sun, Alex Valenzuela, Xueyu Sang, Yaping Zhang, Ondrej Uher, Jan Zenka, Karel Pacak, Zhengping Zhuang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-17 (2023)
Abstract Background Autologous tumor cell-based vaccines (ATVs) aim to prevent and treat tumor metastasis by activating patient-specific tumor antigens to induce immune memory. However, their clinical efficacy is limited. Mannan-BAM (MB), a pathogen-
Externí odkaz:
https://doaj.org/article/7abf8529748b422b80452f431e6eae1e
Autor:
Juan Ye, Yaping Zhang, Mitchell Y Sun, Alex Valenzuela, Herui Wang, Xueyu Sang, Zhengping Zhuang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/f0093a74ee5048caa824500630e0f2aa
Autor:
LaYow C. Yu, Danielle D. Dang, Sophie Zhuang, Shuran Chen, Zhengping Zhuang, Jared S. Rosenblum
Publikováno v:
Cancer Pathogenesis and Therapy, Vol 1, Iss 2, Pp 111-115 (2023)
Carrimycin is a synthetic macrolide antibiotic that has been shown to have anti-cancer activity; however, its exact mechanism of action and molecular target were previously unknown. It was recently elucidated that Isovalerylspiramycin I (ISP I), the
Externí odkaz:
https://doaj.org/article/9651752da30841468a61fc6288919109
Autor:
Samik Chakraborty, Juan Ye, Herui Wang, Mitchell Sun, Yaping Zhang, Xueyu Sang, Zhengping Zhuang
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Toll-like receptors (TLRs) are pattern recognition receptors (PRRs) expressed in various immune cell types and perform multiple purposes and duties involved in the induction of innate and adaptive immunity. Their capability to propagate immunity make
Externí odkaz:
https://doaj.org/article/cd4df9ed47114988a521888ff7c92ce1
Autor:
Danielle D. Dang, Vikram Chandrashekhar, Vibhu Chandrashekhar, Nagela Ghabdanzanluqui, Russell H. Knutsen, Matthew A. Nazari, Likitha Nimmagadda, Danielle R. Donahue, Dorian B. McGavern, Beth A. Kozel, John D. Heiss, Karel Pacak, Zhengping Zhuang, Jared S. Rosenblum
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102367- (2023)
Summary: Mapping cranial vasculature and adjacent neurovascular interfaces in their entirety will enhance our understanding of central nervous system function in any physiologic state. We present a workflow to visualize in situ murine vasculature and
Externí odkaz:
https://doaj.org/article/ae9471c45db847b68da91dbec8d63a83
Autor:
Feiqiong Gao, Qigu Yao, Jiaqi Zhu, Wenyi Chen, Xudong Feng, Bing Feng, Jian Wu, Karel Pacak, Jared Rosenblum, Jiong Yu, Zhengping Zhuang, Hongcui Cao, Lanjuan Li
Publikováno v:
Pharmacological Research, Vol 194, Iss , Pp 106851- (2023)
Hypoxia-inducible factor-2α (HIF-2α) is a transcription factor responsible for regulating genes related to angiogenesis and metabolism. This study aims to explore the effect of a previously unreported mutation c.C2473T (p.R825S) in the C-terminal t
Externí odkaz:
https://doaj.org/article/f6a2ecd5f0b04ba1a930d52bb80e0ca6
Publikováno v:
Cancer Biology & Medicine, Vol 19, Iss 10, Pp 1428-1439 (2022)
Protein phosphatases play essential roles as negative regulators of kinases and signaling cascades involved in cytoskeletal organization. Protein phosphatase 2A (PP2A) is highly conserved and is the predominant serine/threonine phosphatase in the ner
Externí odkaz:
https://doaj.org/article/1be5051d52924dcb9bdfbfbf386153f3