Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Zhengming Wu"'
Autor:
Zhengming Wu, Junhui Su, Fu-long Li, Tao Chen, Jaimie Mayner, Adam Engler, Shenghong Ma, Qingquan Li, Kun-Liang Guan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Small cell lung cancer (SCLC) is highly lethal due to its prevalent metastasis. Most SCLCs have inactivating mutations in TP53 and RB1. We find that loss of YAP expression is key for SCLC cells to acquire rapid ameboid migration and high met
Externí odkaz:
https://doaj.org/article/732c3b92988d4b14a5698b812c3e72c0
Autor:
Chenyue Xu, Qiongmei Gao, Zhengming Wu, Weijuan Lou, Xiaoyan Li, Menghui Wang, Nianhong Wang, Qingquan Li
Publikováno v:
Translational Oncology, Vol 26, Iss , Pp 101540- (2022)
Background: Oncogenic mutations in the KRAS gene are very common in human cancers, resulting in cells with well-characterized selective advantages. For more than three decades, the development of effective therapeutics to inhibit KRAS-driven tumorige
Externí odkaz:
https://doaj.org/article/69745a29cafb4158a61daf72c24a2908
Autor:
ZunGuo Du, XiuJuan Liu, Tao Chen, WenChao Gao, ZhengMing Wu, ZhiQian Hu, Dong Wei, ChunFang Gao, QingQuan Li
Publikováno v:
Cell Reports, Vol 22, Iss 10, Pp 2677-2689 (2018)
Summary: A major obstacle for successful management of patients with colorectal carcinoma (CRC) is resistance to anti-cancer cytotoxic treatments. Here, we identified a mechanism of multidrug resistance in wild-type Kras CRCs based on the survival of
Externí odkaz:
https://doaj.org/article/9442e164e9804b8fbacb283230af3192
Autor:
QingQuan Li, DanFeng Xu, Hai Huang, XiuJuan Liu, ZhengMing Wu, WenChao Gao, ZunGuo Du, Lu Chen, Yi Gao
Figure S5 shows the effects of GAD65 knockdown on CRPC growth and progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f436d7df814315a543f0ed1b9362d6a
https://doi.org/10.1158/0008-5472.22421255
https://doi.org/10.1158/0008-5472.22421255
Autor:
QingQuan Li, DanFeng Xu, Hai Huang, XiuJuan Liu, ZhengMing Wu, WenChao Gao, ZunGuo Du, Lu Chen, Yi Gao
Table S1 shows the detailed information of PDX lines used in this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180cfdcf875a31c856a685bcdeddd1e5
https://doi.org/10.1158/0008-5472.22421249
https://doi.org/10.1158/0008-5472.22421249
Autor:
QingQuan Li, DanFeng Xu, Hai Huang, XiuJuan Liu, ZhengMing Wu, WenChao Gao, ZunGuo Du, Lu Chen, Yi Gao
Supplementary Materials and Methods shows the Extended materials and methods used in this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9980588ddb180b1b03f0a3f2e558e35a
https://doi.org/10.1158/0008-5472.22421252
https://doi.org/10.1158/0008-5472.22421252
Autor:
Zhengming Wu, Kun-Liang Guan
Publikováno v:
Molecular cell. 82(22)
Using multi-omics approaches, Park et al. show that reduced cellular acetyl-CoA and protein hypoacetylation promote liver cancer growth and dedifferentiation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f1eeb052fa59c6c40bfab6fa53bcaee
https://pubmed.ncbi.nlm.nih.gov/36400006
https://pubmed.ncbi.nlm.nih.gov/36400006
Autor:
Kun-Liang Guan, Zhengming Wu
Publikováno v:
Trends Biochem Sci
Hippo pathway components are structurally and functionally conserved and are notable for their role in controlling organ size. More diverse functions of the Hippo pathway have been recognized, including development, tissue homeostasis, wound healing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3521ae22d2bf107dc73e9bff3afce663
https://doi.org/10.1016/j.tibs.2020.08.008
https://doi.org/10.1016/j.tibs.2020.08.008