Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Zhenglin Zhu"'
Autor:
Guizheng Wei, Ke Lu, Muhammad Umar, Zhenglin Zhu, William W. Lu, John R. Speakman, Yan Chen, Liping Tong, Di Chen
Publikováno v:
Bone Research, Vol 11, Iss 1, Pp 1-16 (2023)
Abstract Although aging has traditionally been viewed as the most important risk factor for osteoarthritis (OA), an increasing amount of epidemiological evidence has highlighted the association between metabolic abnormalities and OA, particularly in
Externí odkaz:
https://doaj.org/article/f878b6d1fdee40d0a02ba2fbca9800e3
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9520 (2024)
The Ficus genus, having radiated from the tropics and subtropics to the temperate zone worldwide, is the largest genus among woody plants, comprising over 800 species. Evolution of the Ficus species results in genetic diversity, global radiation and
Externí odkaz:
https://doaj.org/article/a791bfb161d24e619cefd97aed3c6b09
Autor:
Junyi Liao, Bowen Chen, Zhenglin Zhu, Chengcheng Du, Shengqiang Gao, Guozhi Zhao, Piao Zhao, Yonghui Wang, Annie Wang, Zander Schwartz, Lily Song, Jeffrey Hong, William Wagstaff, Rex C. Haydon, Hue H. Luu, Jiaming Fan, Russell R. Reid, Tong-Chuan He, Lewis Shi, Ning Hu, Wei Huang
Publikováno v:
Genes and Diseases, Vol 10, Iss 4, Pp 1351-1366 (2023)
Recent advances in deep sequencing technologies have revealed that, while less than 2% of the human genome is transcribed into mRNA for protein synthesis, over 80% of the genome is transcribed, leading to the production of large amounts of noncoding
Externí odkaz:
https://doaj.org/article/578f419536f7488ab664e00e601ede51
Autor:
Zhenglin Zhu, Shengqiang Gao, Hui Zhu, Yi Chen, Dandong Wu, Zhiyu Chen, Yanran Huang, Xiangdong Wu, Ning Hu, Di Chen, Wei Huang, Hong Chen
Publikováno v:
Journal of Orthopaedic Translation, Vol 40, Iss , Pp 92-103 (2023)
Background: Emerging studies have suggested an essential role of fibroblast metabolic reprogramming in the pathogenesis of arthrofibrosis. The metabolic modulator metformin appears to be a therapeutic candidate for fibrotic disorders. However, whethe
Externí odkaz:
https://doaj.org/article/d93f9481647d46f6bf4bb541fc49c405
Autor:
Chengcheng Du, Qiang Cheng, Piao Zhao, Claire Wang, Zhenglin Zhu, Xiangdong Wu, Shengqiang Gao, Bowen Chen, Jing Zou, Wei Huang, Junyi Liao
Publikováno v:
Genes and Diseases, Vol 10, Iss 3, Pp 1040-1054 (2023)
BMP9 mediated osteogenic differentiation mechanisms of MSCs were widely explored, however, mechanisms of BMP9-induced angiogenesis still need to be clarified. We previously characterized that Notch1 promoted BMP9-induced osteogenesis–angiogenesis c
Externí odkaz:
https://doaj.org/article/a444a42bbfdc4915bdf9ef2342b9f7a2
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 4697-4705 (2023)
Bioinformatics has been playing a crucial role in the scientific progress to fight against the pandemic of the coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The advances in novel algor
Externí odkaz:
https://doaj.org/article/15f329a9c2b5404387a3a422666da0f7
Autor:
Zhenglin Zhu, Yanran Huang, Jun Li, Dan Yi, Junyi Liao, Jun Xiao, Guozhi Xiao, Liping Tong, Wei Huang, Chen Di
Publikováno v:
Journal of Orthopaedic Translation, Vol 38, Iss , Pp 158-166 (2023)
Background: Osteoarthritis (OA) is a common degenerative joint disease with significant negative impact on the quality of life. It has been reported that abnormal upregulation of β-catenin signaling could lead to OA development; however, the upstrea
Externí odkaz:
https://doaj.org/article/bc7158c9b18343e091fdf3e8bd158d87
Autor:
Shengqiang Gao, Bowen Chen, Zhenglin Zhu, Chengcheng Du, Jing Zou, Yaji Yang, Wei Huang, Junyi Liao
Publikováno v:
Stem Cell Research, Vol 66, Iss , Pp 103010- (2023)
Bone morphogenetic protein 2 (BMP2) effectively induced mesenchymal stem cells (MSCs) osteogenic differentiation hold great potential for bone tissue engineering. However, a global mechanistic view of BMP2-induced osteogenic differentiation of MSCs r
Externí odkaz:
https://doaj.org/article/98daf1d5bb1640ba8c260126794ca1db
Publikováno v:
Frontiers in Energy Research, Vol 10 (2022)
With the expansion of scale of the grid-connected wind power, wind power forecasting plays an increasing important role in ensuring the security and steady operation and instructing the dispatch of power systems. In consideration of the randomness an
Externí odkaz:
https://doaj.org/article/8c40c82f061f41bc8aadf70c1a4bef9a
Autor:
Pengcheng Xiao, Zhenglin Zhu, Chengcheng Du, Yongsheng Zeng, Junyi Liao, Qiang Cheng, Hong Chen, Chen Zhao, Wei Huang
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-16 (2021)
Abstract Background Bone morphogenetic protein 2 (BMP2) is a promising chondrogenic growth factor for cartilage tissue-engineering, but it also induces robust endochondral ossification. Human synovial-derived mesenchymal stromal cells (hSMSCs) have a
Externí odkaz:
https://doaj.org/article/84cd4192810c4ae1bcfe77d387e67770