Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Zhenglin Ou"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Given the increasing incidence of pancreatic cancer and the low survival rate, the exploration of the complex tumor microenvironment and the development of novel treatment options is urgent. NK cells, known for their cytotoxic abilities and modulatio
Externí odkaz:
https://doaj.org/article/e6b21a785fd14d2085c46af1cad5afc7
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Due to the abnormal vasculation and proliferation, the tumor microenvironment is hypoxic, lacking nutrients, and under high interstitial pressure. Compared to oxygen and nutrients, the effect of pressure on cancer biology remains poorly stud
Externí odkaz:
https://doaj.org/article/dcc712862c0f4f06af4dace9ca010947
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Radiotherapy and chemotherapy can arrest cancer cells in a senescence-like state, which can lead to therapy resistance and cancer relapse. mTOR is hyperactivated in senescent cells but the mechanisms remain unclear. In this study, we examine the role
Externí odkaz:
https://doaj.org/article/2bebfccdfad14a949a94f15b657b1f2e
Publikováno v:
Journal of Immunology Research, Vol 2021 (2021)
Background. Extracellular vesicles (EVs) can deliver miRNAs between cells and play a crucial role in hepatoblastoma progression. In this study, we explored the differentially expressed miRNAs related to tumor cell-derived EVs and the mechanism by whi
Externí odkaz:
https://doaj.org/article/c726f01ecbc5458a8b2d70cd94332c4f
Publikováno v:
Mediators of Inflammation, Vol 2021 (2021)
Background. Hepatoblastoma (HB) is the most common liver malignancy in pediatrics, but the treatment for this disease is minimal. This study is aimed at exploring the effect of FoxO1 and SREBP-1c on HB and their mechanism. Methods. FoxO1, SREBP-1c, F
Externí odkaz:
https://doaj.org/article/d5328cd0b87444fab354ee8965c53f00
Publikováno v:
World Journal of Gastroenterology
BACKGROUND Long non-coding RNA (lncRNA) is abnormally expressed in various malignant tumors. In recent years, it has been found that IncRNA HULC is increasingly expressed in pancreatic cancer tissues and is involved in the development and progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11ca257ecdeac13ea1cd66b3c1413932
https://doi.org/10.3748/wjg.v25.i46.6728
https://doi.org/10.3748/wjg.v25.i46.6728
Publikováno v:
Cancer Management and Research
Neng Tang,1,2 Xiaolin Dou,1,2 Xing You,1,2 Guodong Liu,1,2 Zhenglin Ou,1,2,* Hongyan Zai1,2,* 1Department of General Surgery, Xiangya Hospital Central South University, Changsha, 410008, Hunan Province, Peopleâs Republic of China; 2Natio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb7964043e37a1185009e376b4ac0d60
https://www.dovepress.com/comparisons-of-outcomes-between-adolescent-and-young-adult-with-older--peer-reviewed-fulltext-article-CMAR
https://www.dovepress.com/comparisons-of-outcomes-between-adolescent-and-young-adult-with-older--peer-reviewed-fulltext-article-CMAR
Radiotherapy and chemotherapy can arrest cancer cells in a senescence-like state, which can lead to therapy resistance and cancer relapse. Despite the cell cycle arrest, senescence-like cells have persistent mTOR activity that is insensitive to nutri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::849a6fa7c1fead0903078b057fa67d72
https://doi.org/10.21203/rs.3.rs-1014270/v1
https://doi.org/10.21203/rs.3.rs-1014270/v1
Publikováno v:
Journal of oncology. 2022
Background. Hepatoblastoma (HB) is the most common malignant tumor of the liver. MMP9 plays an essential role in HB. The purpose of our study was to screen for differentially expressed lncRNAs and miRNAs that targeted MMP9. Based on this, the role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaf2b13368cc8a1dd1e1d562daeb9ca9
https://pubmed.ncbi.nlm.nih.gov/35300348
https://pubmed.ncbi.nlm.nih.gov/35300348
Publikováno v:
Journal of Cellular Physiology. 234:15407-15419
Nowadays, pancreatic cancer (PC) remains the most lethal tumor, partially due to the invasive and treatment-resistant phenotype induced by the extent of hypoxic stress within the tumor tissue. According to previous studies, miR-142/HIF-1α and miR-13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c329c2d4af3557dad7b6631de4d1d23
https://doi.org/10.1002/jcp.28188
https://doi.org/10.1002/jcp.28188