Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Zhenghong Lin"'
Publikováno v:
Heliyon, Vol 10, Iss 8, Pp e29567- (2024)
XIAP, or the X-linked Inhibitor of Apoptosis Protein, is the most extensively studied member within the IAP gene family. It possesses the capability to impede apoptosis through direct inhibition of caspase activity. Various kinds of cancers overexpre
Externí odkaz:
https://doaj.org/article/b084c6d516fc41ebb59f638d7ae01f8f
Autor:
Zhenghong Lin, Xiaohua Yan
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/3edf6f54bdf846e69a49dbbcbee1645b
Autor:
Tiantian Che, Zhenghong Lin
Publikováno v:
Clinical and Translational Discovery, Vol 2, Iss 2, Pp n/a-n/a (2022)
Abstract Ubiquitination, a highly versatile process of protein homeostasis, participates in the degradation of the vast majority of cellular proteins. In addition to proteolytic function, ubiquitination can also conduce to modulate cellular processes
Externí odkaz:
https://doaj.org/article/82a3f37f439144d389a8ef72a9e44252
Autor:
Ling Dong, Le Yu, Hui Li, Lei Shi, Zhong Luo, Huakan Zhao, Zhaojian Liu, Guobing Yin, Xiaohua Yan, Zhenghong Lin
Publikováno v:
iScience, Vol 23, Iss 8, Pp 101351- (2020)
Summary: Ubiquitin specific protease 39 (USP39), an ortholog of Sad1p in yeast, is essential for spliceosome assembly during pre-mRNA splicing in human. Although it is known that USP39 is upregulated and plays an oncogenic role in hepatocellular carc
Externí odkaz:
https://doaj.org/article/2f361c8bfbac4c7d867ee35d43852352
Publikováno v:
Biomedicines, Vol 9, Iss 9, p 1143 (2021)
The overexpression of adenosine triphosphate (ATP)-binding cassette (ABC) subfamily B member 1 (ABCB1; P-glycoprotein; MDR1) in some types of cancer cells is one of the mechanisms responsible for the development of multidrug resistance (MDR), which l
Externí odkaz:
https://doaj.org/article/6984c543d5da43309544b9c70f221ab4
Publikováno v:
PeerJ, Vol 5, p e3751 (2017)
Background Cold atmospheric-pressure plasma (CAP) has been considered a promising strategy for anti-cancer treatment. Traditionally, CAP was employed to kill cancer cells or tumor tissues by direct irradiation. However, CAP has some disadvantages suc
Externí odkaz:
https://doaj.org/article/ce8e55ed9d4f49c8831416ef955243f2
Autor:
Zhenghong Lin, Heeyoung Yang, Can Tan, Jinping Li, Zhaojian Liu, Qiu Quan, Sinyi Kong, Junsheng Ye, Beixue Gao, Deyu Fang
Publikováno v:
Cell Reports, Vol 5, Iss 6, Pp 1639-1649 (2013)
The reduced protein expression of SIRT6 tumor suppressor is involved in tumorigenesis. The molecular mechanisms underlying SIRT6 protein downregulation in human cancers remain unknown. Using a proteomic approach, we have identified the ubiquitin-spec
Externí odkaz:
https://doaj.org/article/05000bb8bdf8440aadd8b59780af9311
Publikováno v:
IEEE Transactions on Multimedia. :1-14
Publikováno v:
Information Sciences. 612:563-575
Autor:
Weicheng Luo, Yi Li, Yi Zeng, Yining Li, Minzhang Cheng, Cheng Zhang, Fei Li, Yiqing Wu, Chunhong Huang, Xiaolong Yang, Joachim Kremerskothen, Jianmin Zhang, Chunbo Zhang, Shuo Tu, Zhihua Li, Zhijun Luo, Zhenghong Lin, Xiaohua Yan
Publikováno v:
Journal of Molecular Cell Biology.
Tea domain transcriptional factor 4 (TEAD4) plays a pivotal role in tissue development and homeostasis by interacting with YAP in response to Hippo signaling inactivation. TEAD4 and YAP can also cooperate with TGF-β-activated Smad proteins to regula