Zobrazeno 1 - 10 of 22 pro vyhledávání: '"Zhenggen Liao"'
1
Akademický článek
Effect of carrier materials on the properties of the andrographolide solid dispersion
Autor: Shoude Zhang, Qingyun Zeng, Guowei Zhao, Wei Dong, Liquan Ou, Ping Cai, Zhenggen Liao, Xinli Liang
Publikováno v: Brazilian Journal of Pharmaceutical Sciences, Vol 58 (2022)
Abstract In the work the andrographolide (AG)-solid dispersions (SDs) were prepared by the spray-drying method, using polyethylene glycol 8000 (PEG8000), Poloxamer188, polyvinylpyrrolidone K30 (PVPK30), Soluplus® as carrier materials. The effect of
Externí odkaz: https://doaj.org/article/f45fb706ab6f4b2eb5939957a04d752a
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2
Akademický článek
Preparation and Characterization of PEG4000 Palmitate/PEG8000 Palmitate-Solid Dispersion Containing the Poorly Water-Soluble Drug Andrographolide
Autor: Qingyun Zeng, Liquan Ou, Guowei Zhao, Ping Cai, Zhenggen Liao, Wei Dong, Xinli Liang
Publikováno v: Advances in Polymer Technology, Vol 2020 (2020)
Solid dispersion (SD) is the effective approach to improve the dissolution rate and bioavailability of class II drugs with low water solubility and high tissue permeability in the Biopharmaceutics Classification System. This study investigated the ef
Externí odkaz: https://doaj.org/article/80309e519ced4255afa82a9bd9c0661d
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3
Akademický článek
Effect of Carrier Lipophilicity and Preparation Method on the Properties of Andrographolide–Solid Dispersion
Autor: Guowei Zhao, Qingyun Zeng, Shoude Zhang, Youquan Zhong, Changhao Wang, Yashao Chen, Liquan Ou, Zhenggen Liao
Publikováno v: Pharmaceutics, Vol 11, Iss 2, p 74 (2019)
Solid dispersion (SD) is a useful approach to improve the dissolution rate and bioavailability of poorly water-soluble drugs. This work investigated the effects of carrier material lipophilicity and preparation method on the properties of andrographo
Externí odkaz: https://doaj.org/article/d199155476d54cc6956e5395db3d048d
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4
Akademický článek
Preparation, Characterization, and Pharmacokinetic Evaluation of Imperatorin Lipid Microspheres and Their Effect on the Proliferation of MDA-MB-231 Cells
Autor: Xinli Liang, Xulong Chen, Guowei Zhao, Tao Tang, Wei Dong, Chunyan Wang, Jing Zhang, Zhenggen Liao
Publikováno v: Pharmaceutics, Vol 10, Iss 4, p 236 (2018)
Imperatorin is a chemical compound belonging to the linear furanocoumarins. Imperatorin is attracting considerable attention because of its antitumor, antibacterial, anti-inflammatory, and anticoagulant activities, inhibition of myocardial hypertroph
Externí odkaz: https://doaj.org/article/7f7b1f4b6de2432e91a3a07473badbee
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5
Akademický článek
In vitro metabolism and inhibitory effects of atractylenolide II on various hepatic CYPs in HLMs.
Autor: Xulong Chen1,2,3, Zhenggen Liao1, Cheng Li2,3, Guoyong Huang1, Yunyan Song1, Wei Dong1, Abid Naeem1, Xinli Liang1 paln7@163.com
Publikováno v: Journal of Chinese Pharmaceutical Sciences. Aug2021, Vol. 30 Issue 8, p645-656. 12p.
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6
Effect of carrier material on the thermodynamic properties and recrystallization kinetics of andrographolide-solid dispersion
Autor: Guowei, Zhao, Junfang, Zhang, Ping, Cai, Liquan, Ou, Xinli, Liang, Wei, Dong, Zhenggen, Liao
Publikováno v: Journal of Pharmacy and Pharmacology. 74:761-768
Objectives This work investigated the effect of the lipophilic long carbon chain of carrier material on the thermodynamic properties and the recrystallization kinetics of solid dispersion (SD). Methods The thermodynamic properties and recrystallizati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0095a76f481aea5610c7efd581c71869
https://doi.org/10.1093/jpp/rgab179
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8
Effect and molecular mechanism research of
Autor: Xulong, Chen, Xinli, Liang, Xiaoqiang, Kong, Miaomiao, Ji, Abid, Naeem, Cheng, Li, Hao, Zheng, Mingxia, Gao, Zhenggen, Liao
Publikováno v: Chinese herbal medicines. 14(1)
To investigate the effect and the mechanism ofFour-week-old male Sprague-Dawley rats were fed with Xiaochengqi Decoction to induce the spleen deficiency model for 40 d. Single-pass intestinal perfusion model were used to study the effects of HQ extra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::903caf0764b996b69aad6a11982753f9
https://pubmed.ncbi.nlm.nih.gov/36120137
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9
Effect of Baizhu (Rhizoma Atractylodis Macrocephalae) extract on intestinal absorption of brucine and strychnine in vitro and in situ
Autor: Dan, Lü, Qieying, Jiang, Jing, Zhang, Ronggui, Zeng, Zhenggen, Liao, Xinli, Liang
Publikováno v: Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan. 40(4)
To investigate the antagonistic effect of the extract of Baizhu (Rhizoma Atractylodis Macrocephalae) (RAM) on the intestinal absorption of brucine and strychnine in Strychnos nux-vomica (NUX) and propose the mechanism of these effects.The apparent pe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::358e6931e2a6bb73e9f59ad7b1036809
https://pubmed.ncbi.nlm.nih.gov/32744023
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