Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Zhengcai, Du"'
Autor:
Jiageng Guo, Xinya Jiang, Jing Lian, Huaying Li, Fan Zhang, Jinling Xie, Jiagang Deng, Xiaotao Hou, Zhengcai Du, Erwei Hao
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
The PI3K/AKT/GSK-3β signaling pathway plays a pivotal role in numerous physiological and pathological processes, including cell proliferation, apoptosis, differentiation, and metabolic regulation. Aberrant activation of the PI3K/AKT pathway is intri
Externí odkaz:
https://doaj.org/article/3c84d6e9fdfc4cfe999ee9599ed7be00
Autor:
Xianglong Pan, Erwei Hao, Fan Zhang, Wei Wei, Zhengcai Du, Guangli Yan, Xijun Wang, Jiagang Deng, Xiaotao Hou
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Diabetic cardiomyopathy (DCM) is a specific heart condition in diabetic patients, which is a major cause of heart failure and significantly affects quality of life. DCM is manifested as abnormal cardiac structure and function in the absence of ischae
Externí odkaz:
https://doaj.org/article/3d5abaf4e3e346bcb4b483b9ccf789cd
Autor:
Jieyi Yang, Jiageng Guo, Peiling Tang, Shidu Yan, Xiaodong Wang, Huaying Li, Jinling Xie, Jiagang Deng, Xiaotao Hou, Zhengcai Du, Erwei Hao
Publikováno v:
Pharmaceuticals, Vol 17, Iss 9, p 1176 (2024)
The skin barrier is essential for maintaining the body’s internal homeostasis, protecting against harmful external substances, and regulating water and electrolyte balance. Traditional Chinese Medicine (TCM) offers notable advantages in restoring s
Externí odkaz:
https://doaj.org/article/604e33f70ec54b4a996080149affc301
Autor:
Jing Lian, Dongxin Lin, Yuchan Huang, Xiaohui Chen, Lian Chen, Fan Zhang, Peiling Tang, Jinling Xie, Xiaotao Hou, Zhengcai Du, Jiagang Deng, Erwei Hao, Junhui Liu
Publikováno v:
Chinese Medicine, Vol 18, Iss 1, Pp 1-19 (2023)
Abstract Tumours do not exist in isolation from the organism; their growth, proliferation, motility, and immunosuppressive response are intricately connected to the tumour’s microenvironment. As tumour cells and the microenvironment coevolve, an in
Externí odkaz:
https://doaj.org/article/382bf8e85e344293a0553be77f31f773
Autor:
Xianglong Pan, Xiaotao Hou, Fan Zhang, Peiling Tang, Wanruo Wan, Zixia Su, Yeguo Yang, Wei Wei, Zhengcai Du, Jiagang Deng, Erwei Hao
Publikováno v:
Pharmaceutical Biology, Vol 60, Iss 1, Pp 915-930 (2022)
Context Gnetum montanum Markgr. (Gnetaceae) is used to treat rheumatic arthralgia and bruises in the clinic.Objective To exam the activity and mechanism of G. montanum extract (GME) against colon cancer cells SW480.Materials and methods The anti-prol
Externí odkaz:
https://doaj.org/article/237b03f84eee49d79dec115ac45dfeda
Autor:
Lei Xia, Fan Zhang, Yulu Li, Yuemi Mo, Lingqiu Zhang, Qianhua Li, Minghuang Luo, Xiaotao Hou, Zhengcai Du, Jiagang Deng, Erwei Hao
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
As a neurodegenerative disease, Alzheimer’s disease (AD) is characterized by synaptic loss, extracellular plaques of amyloid accumulation, hyperphosphorylation of tau, and neuroinflammation. Various biological processes are affected by epitranscrip
Externí odkaz:
https://doaj.org/article/59b018693489495dafbe3581cde05e19
Autor:
Yuchan Huang, Shidu Yan, Zixia Su, Lei Xia, Jinling Xie, Fan Zhang, Zhengcai Du, Xiaotao Hou, Jiagang Deng, Erwei Hao
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Aquaporins (AQPs) are a family of transmembrane proteins expressed in various organ systems. Many studies have shown that the abnormal expression of AQPs is associated with gastrointestinal, skin, liver, kidneys, edema, cancer, and other diseases. Th
Externí odkaz:
https://doaj.org/article/006d8d5c59c84def867f176f87c16a3e
Autor:
Shidu Yan, Yuchan Huang, Qian Xiao, Zixia Su, Lei Xia, Jinling Xie, Fan Zhang, Zhengcai Du, Xiaotao Hou, Jiagang Deng, Erwei Hao
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
In recent years, activation of thermal transient receptor potential (TRP) ion channels at a range of temperatures has received widespread attention as a target for traditional Chinese medicine (TCM) to regulate body temperature and relieve pain. Disc
Externí odkaz:
https://doaj.org/article/985a1f39665749668bd538c58216adef
Autor:
Liuying Mo, Fan Zhang, Feng Chen, Lei Xia, Yi Huang, Yuemi Mo, Lingqiu Zhang, Daquan Huang, Shunli He, Jiagang Deng, Erwei Hao, Zhengcai Du
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Tetrandrine (Tet), derived from the traditional Chinese herb Fangji, is a class of natural alkaloids with the structure of bisbenzylisoquinoline, which has a wide range of physiological activities and significant pharmacfological effects. However, st
Externí odkaz:
https://doaj.org/article/b72b19787aa24ed8a9eac6d19332f3f3
Autor:
Zhongshang Xia, Erwei Hao, Zhangmei Chen, Mingzhe Zhang, Yanting Wei, Man Wei, Xiaotao Hou, Zhengcai Du, Jiagang Deng
Publikováno v:
Pharmaceutical Biology, Vol 58, Iss 1, Pp 1303-1310 (2020)
Context Although the roots and stems of Kadsura coccinea (Lem.) A. C. Smith. [Schisandraceae] are herbs and traditional foods in Li nationality, its toxicity remains unclear. Objective To study developmental toxicity of K. coccinea consumption and ex
Externí odkaz:
https://doaj.org/article/e82aca815a124904873c4762d92e8e17