Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Zhengbin, Chai"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The peptidyl arginine deiminase (PADI) family is a calcium ion-dependent group of isozymes with sequence similarity that catalyze the citrullination of proteins. Histones can serve as the target substrate of PADI family isozymes, and therefore, the P
Externí odkaz:
https://doaj.org/article/1add477faf55412f81d0bb4a77adc6a4
Autor:
Heng Zhao, Nuohan Song, Hao Feng, Qiang Lei, Yingying Zheng, Jing Liu, Chunyan Liu, Zhengbin Chai
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundThe increasing incidence of gastrointestinal stromal tumors (GISTs) has led to the discovery of more novel prognostic markers. We aim to establish an unsupervised prognostic model for the early prediction of the prognosis of future patients
Externí odkaz:
https://doaj.org/article/5474521890224714ad8d417df76844c1
Autor:
Changhui Zhu, Xue Dong, Xiwei Wang, Yingying Zheng, Juanjuan Qiu, Yanling Peng, Jiajun Xu, Zhengbin Chai, Chunyan Liu
Publikováno v:
Genetics Research, Vol 2022 (2022)
Sirtuin 2 (SIRT2), as a member of the sirtuin family, has representative features of evolutionarily highly conserved nicotinamide adenine dinucleotide (NAD+)-dependent deacetylase activity. In addition, SIRT2, as the only sirtuin protein colocalized
Externí odkaz:
https://doaj.org/article/b42aeee73de54dba9cda16326a1d1543
Autor:
Xiaotian Chang, Zhengbin Chai, Jiaorui Zou, Hongxing Wang, Yao Wang, Yabing Zheng, Hui Wu, Chunyan Liu
Publikováno v:
Cancer Biology & Medicine, Vol 16, Iss 4, Pp 729-742 (2019)
Objective As a member of the peptidyl arginine deiminase (PAD) family, PADI3 is weakly expressed in colon cancer tissues and highly expressed in adjacent colon cancer tissues. However, the role of PADI3 in colon cancer is unclear. In this study, we i
Externí odkaz:
https://doaj.org/article/cfd27975020f4d9babf45ed45ea316f0
Autor:
Zhengbin Chai, Li Wang, Yabing Zheng, Na Liang, Xiwei Wang, Yingying Zheng, Zhiwei Zhang, Chuanxi Zhao, Tingting Zhu, Chunyan Liu
Publikováno v:
Cancer Cell International, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background CKS1 is highly expressed in colon cancer tissues, and is essential for cancer cell proliferation. The downstream molecular mechanism of CKS1 has been fully studied, but the upstream regulatory mechanism of it is still unclear. Ear
Externí odkaz:
https://doaj.org/article/da4b8922f962422b9575251a679af2b3
Autor:
Cheng Wang, Liangxing Zhou, Mei Mo, Xianglin Kong, Zhengbin Chai, Lei Deng, Junli Zhang, Kuan Cao, Chuanfei Wei, Li Xu, Juanli Chen, Fabin Han
Publikováno v:
Brain Science Advances. 7:207-219
Lycium barbarum polysaccharides (LBPs) are the major polysaccharides extracted from L. barbarum, which is used in traditional Chinese medicine (TCM) for treating diseases. Studies have shown that LBPs have important biological activities, such as ant
Autor:
Liangxing, Zhou, Mengpeng, Li, Zhengbin, Chai, Junli, Zhang, Kuan, Cao, Lei, Deng, Yanming, Liu, Cun, Jiao, Gang-Ming, Zou, Jibiao, Wu, Fabin, Han
Publikováno v:
Oncology Reports. 49
Autor:
Xiwei Wang, Yingying Zheng, Zhengbin Chai, Ji Li, Changhui Zhu, Yanling Peng, Juanjuan Qiu, Jiajun Xu, Chunyan Liu
Publikováno v:
Molecular carcinogenesisREFERENCES.
Dihydroartemisinin (DHA) has recently attracted increasing attention for its low toxicity and high antitumor activity. DHA has been reported to have synergistic anticancer effects with a variety of drugs in the clinic; however, the molecular mechanis
Autor:
Chunyan Liu, Xiaotian Chang, Jiaorui Zou, Yao Wang, Zhengbin Chai, Hui Wu, Yabing Zheng, Hongxing Wang
Publikováno v:
Cancer Biology & Medicine, Vol 16, Iss 4, Pp 729-742 (2019)
Cancer Biology & Medicine
Cancer Biology & Medicine
Objective: As a member of the peptidyl arginine deiminase (PAD) family, PADI3 is weakly expressed in colon cancer tissues andhighly expressed in adjacent colon cancer tissues. However, the role of PADI3 in colon cancer is unclear. In this study, wein
Autor:
Wang Xiwei, Zhengbin Chai, Chunyan Liu, Tingting Zhu, Zheng Yingying, Li Wang, Liang Na, Zhiwei Zhang, Chuanxi Zhao, Yabing Zheng
Publikováno v:
Cancer Cell International, Vol 19, Iss 1, Pp 1-11 (2019)
Cancer Cell International
Cancer Cell International
Background CKS1 is highly expressed in colon cancer tissues, and is essential for cancer cell proliferation. The downstream molecular mechanism of CKS1 has been fully studied, but the upstream regulatory mechanism of it is still unclear. Earlier rese