Zobrazeno 1 - 10
of 227
pro vyhledávání: '"Zheng-qin Yin"'
Publikováno v:
International Journal of Ophthalmology, Vol 16, Iss 4, Pp 483-498 (2023)
AIM: To explore whether the subretinal transplantation of retinal progenitor cells from human embryonic stem cell-derived retinal organoid (hERO-RPCs) could promote Müller glia dedifferentiation and transdifferentiation, thus improving visual functi
Externí odkaz:
https://doaj.org/article/ef5837d42bc7493591bc73a7ebb4c2e0
Publikováno v:
BMC Ophthalmology, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Human umbilical cord mesenchymal stem cells (UCMSCs) transplantation is a promising therapy for the treatment of retinitis pigmentosa (RP). However, intravenously infused cells may be blocked in the lung, increasing the risk of va
Externí odkaz:
https://doaj.org/article/4a2166d69a3340fca0d6a434f746211c
Publikováno v:
International Journal of Ophthalmology, Vol 14, Iss 8, Pp 1138-1150 (2021)
AIM: To explore the temporal mitochondrial characteristics of retinal pigment epithelium (RPE) cells obtained from human embryonic stem cells (hESC)-derived retinal organoids (hEROs-RPE), to verify the optimal period for using hEROs-RPE as donor cell
Externí odkaz:
https://doaj.org/article/2162b567c2db4665a40c4ffe92f78ffd
Publikováno v:
Journal of Integrative Neuroscience, Vol 22, Iss 3, p 55 (2023)
Background: Glaucoma is the leading cause of irreversible blindness, and the loss of retinal ganglion cells (RGCs) is the most important pathological feature. During the progression of glaucoma, glutamate content in the optic nerve increases, and glu
Externí odkaz:
https://doaj.org/article/691f446cf2f2427fb0b2a3403238351c
Publikováno v:
International Journal of Ophthalmology, Vol 13, Iss 10, Pp 1521-1530 (2020)
AIM: To assess the biosafety of a poly(acrylamide-co-sodium acrylate) hydrogel (PAH) as a 3D-printed intraocular lens (IOL) material. METHODS: The biosafety of PAH was first evaluated in vitro using human lens epithelial cells (LECs) and the ARPE19
Externí odkaz:
https://doaj.org/article/013cc5a585684a618704f1f258acc30b
Autor:
Ting Zou, Lixiong Gao, Yuxiao Zeng, Qiyou Li, Yijian Li, Siyu Chen, Xisu Hu, Xi Chen, Caiyun Fu, Haiwei Xu, Zheng Qin Yin
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Stem cell transplantation to treat retinal degeneration could be limited by the degenerative microenvironment. Here, the authors show that C-Kit+/SSEA4– progenitor cells enriched from human embryonic stem cell derived retinal organoids protect reti
Externí odkaz:
https://doaj.org/article/b3a0a613f39d4b1d8b06d83729d56216
Publikováno v:
SAGE Open Medical Case Reports, Vol 8 (2020)
Macular hemorrhage can occur spontaneously and repeatedly without choroidal neovascularization or other known lesions associated with myopia. We report a case of repeated myopic macular hemorrhage following fish oil supplementation. A 32-year-old mal
Externí odkaz:
https://doaj.org/article/0520148e595e4d7e9c93544879986a7b
Autor:
Wei Zhai, Lixiong Gao, Linghui Qu, Yijian Li, Yuxiao Zeng, Qiyou Li, Haiwei Xu, Zheng Qin Yin
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Retinal degenerative diseases (RDDs) are the leading causes of blindness and currently lack effective treatment. Cytotherapy has become a promising strategy for RDDs. The transplantation of olfactory ensheathing cells (OECs) or neural stem cells (NSC
Externí odkaz:
https://doaj.org/article/758b4bd4efd143e3942a58b0e437dbdc
Publikováno v:
International Journal of Ophthalmology, Vol 11, Iss 5, Pp 756-765 (2018)
AIM: To evaluate the intrinsic excitability of retinal ganglion cells (RGCs) in degenerated retinas. METHODS: The intrinsic excitability of various morphologically defined RGC types using a combination of patch-clamp recording and the Lucifer yellow
Externí odkaz:
https://doaj.org/article/e15e3696ef3b4e2c9161745aecb522b5
Autor:
Yong Liu, Shao Jun Chen, Shi Ying Li, Ling Hui Qu, Xiao Hong Meng, Yi Wang, Hai Wei Xu, Zhi Qing Liang, Zheng Qin Yin
Publikováno v:
Stem Cell Research & Therapy, Vol 8, Iss 1, Pp 1-12 (2017)
Abstract Background Retinitis pigmentosa is a common genetic disease that causes retinal degeneration and blindness for which there is currently no curable treatment available. Vision preservation was observed in retinitis pigmentosa animal models af
Externí odkaz:
https://doaj.org/article/9d4ca42b49b04e029e1ca236a553d0ff