Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Zheng-gang Ren"'
Autor:
Zhong-Chen Li, Jie Wang, He-Bin Liu, Yi-Min Zheng, Jian-Hang Huang, Jia-Bin Cai, Lei Zhang, Xin Liu, Ling Du, Xue-Ting Yang, Xiao-Qiang Chai, Ying-Hua Jiang, Zheng-Gang Ren, Jian Zhou, Jia Fan, De-Cai Yu, Hui-Chuan Sun, Cheng Huang, Feng Liu
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113877- (2024)
Summary: Combination therapy (lenvatinib/programmed death-1 inhibitor) is effective for treating unresectable hepatocellular carcinoma (uHCC). We reveal that responders have better overall and progression-free survival, as well as high tumor mutation
Externí odkaz:
https://doaj.org/article/373fb5f605da44d19f76ab1177c0032c
Autor:
Guo-Ming Shi, Xiao-Yong Huang, Dong Wu, Hui-Chuan Sun, Fei Liang, Yuan Ji, Yi Chen, Guo-Huan Yang, Jia-Cheng Lu, Xian-Long Meng, Xin-Ying Wang, Lei Sun, Ning-Ling Ge, Xiao-Wu Huang, Shuang-Jian Qiu, Xin-Rong Yang, Qiang Gao, Yi-Feng He, Yang Xu, Jian Sun, Zheng-Gang Ren, Jia Fan, Jian Zhou
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-10 (2023)
Abstract Advanced intrahepatic cholangiocarcinoma (ICC) has a dismal prognosis. Here, we report the efficacy and safety of combining toripalimab, lenvatinib, and gemcitabine plus oxaliplatin (GEMOX) as first-line therapy for advanced ICC. Thirty pati
Externí odkaz:
https://doaj.org/article/6f29477f8ecc4e3a86a2432ea36affb9
Autor:
Feng Zhang, Shen-Xin Lu, Ke-Shu Hu, Yu-Hong Gan, Yi Chen, Ning-Lin Ge, Bi-Wei Yang, Lan Zhang, Rong-Xin Chen, Zheng-Gang Ren, Xin Yin
Publikováno v:
International Journal of Hyperthermia, Vol 38, Iss 1, Pp 1-10 (2021)
Objective Albumin-to-alkaline phosphatase ratio (AAPR), a newly developed blood biomarker, has been reported to have prognostic value in several types of cancer. This study aimed to investigate the predictive value of AAPR in patients with early-stag
Externí odkaz:
https://doaj.org/article/906b8ec935534ae1b09492e7a78a20a9
Autor:
Xia-Hui Lin, Hua-Hua Liu, Shu-Jung Hsu, Rui Zhang, Jie Chen, Jun Chen, Dong-Mei Gao, Jie-Feng Cui, Zheng-Gang Ren, Rong-Xin Chen
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-17 (2020)
Abstract Background Sustained adrenergic signaling secondary to chronic stress promotes cancer progression; however, the underlying mechanisms for this phenomenon remain unclear. Hepatocellular carcinoma (HCC) frequently develops within fibrotic live
Externí odkaz:
https://doaj.org/article/b09f778ede6643208ed98a99deba491b
Autor:
Jing-huan Li, Xin Yin, Wen-shuai Fan, Lan Zhang, Rong-xin Chen, Yi Chen, Li-xin Li, Ning-ling Ge, Yu-hong Gan, Yan-hong Wang, Zheng-gang Ren
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundPatients with hepatocellular carcinoma (HCC) with main portal vein tumor thrombus (mPVTT) have poor prognosis. Promising systemic therapies, such as target therapies, have limited benefits. The purpose of this study is to retrospectively ev
Externí odkaz:
https://doaj.org/article/385a252f4b7d4f4db66afcf8993ab89e
Autor:
Rui Zhang, Min Ma, Xia-Hui Lin, Hua-Hua Liu, Jie Chen, Jun Chen, Dong-Mei Gao, Jie-Feng Cui, Zheng-Gang Ren, Rong-Xin Chen
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-11 (2018)
Abstract Background Accelerated malignant behaviors induced by insufficient thermal ablation have been increasingly reported, however, the exact mechanisms are still unclear. Here, we investigated the importance of the extracellular matrix (ECM) in m
Externí odkaz:
https://doaj.org/article/1743c3dd9cc146508ad2425f9d332e07
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-13 (2018)
Abstract Background It has been reported mesenchymal stem cells (MSCs) are recruited to and become integral parts of the tumor microenvironment. MSCs might have an active role in solid tumor progression, especially cancer metastasis. However, the con
Externí odkaz:
https://doaj.org/article/c40f61ac947f4d828cca94a1330fd6c3
Autor:
Gang Dong, Qiong‐Dan Zheng, Min Ma, Si‐Fan Wu, Rui Zhang, Rong‐Rong Yao, Yin‐Ying Dong, Hui Ma, Dong‐Mei Gao, Sheng‐Long Ye, Jie‐Feng Cui, Zheng‐Gang Ren, Rong‐Xin Chen
Publikováno v:
Cancer Medicine, Vol 7, Iss 3, Pp 820-830 (2018)
Abstract Transarterial chemoembolization (TACE) is the standard treatment for unresectable hepatocellular carcinoma (HCC). Hypoxia‐induced angiogenesis by TACE is linked to treatment failure; however, whether the chemotherapeutic damage of TACE to
Externí odkaz:
https://doaj.org/article/9308aecb0206439e869da4d4aa51e51a
Autor:
Xin Yin, Bei Tang, Jing-Huan Li, Yan Wang, Lan Zhang, Xiao-Ying Xie, Bo-Heng Zhang, Shuang-Jian Qiu, Wei-Zhong Wu, Zheng-Gang Ren
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 36, Iss 1, Pp 1-13 (2017)
Abstract Background Drug resistance is one of the major concerns in the treatment of hepatocellular carcinoma (HCC). The aim of the present study was to determine whether aberrant high expression of the inhibitor of differentiation 1(ID1) confers oxa
Externí odkaz:
https://doaj.org/article/a57cb9a8228247ada8f126a4cdb21ee6
Autor:
Rui Zhang, Rong-Rong Yao, Jing-Huan Li, Gang Dong, Min Ma, Qiong-Dan Zheng, Dong-Mei Gao, Jie-Feng Cui, Zheng-Gang Ren, Rong-Xin Chen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Some evidences show that residual tumor after thermal ablation will progress rapidly. However, its mechanisms remain unclear. Here, we assessed whether activated HSCs could regulate stem cell-like property of residual tumor after incomplete
Externí odkaz:
https://doaj.org/article/bb00260f81a74f3f93a0171ebfc1dfac