Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Zheng-Yong Wan"'
Autor:
Tian-Qi Mao, Erik De Clercq, Zheng-Yong Wan, Jin Yao, Dirk Daelemans, Fen-Er Chen, Xinlong Wang, Christophe Pannecouque, Hong Yin, Wen-Xue Chen, Haifeng Wang
Publikováno v:
European Journal of Medicinal Chemistry. 102:215-222
Based on molecular simulation, the etravirine-VRX-480773 hybrids previously disclosed by our group were optimized to yield novel pyrimidine sulfonylacetanilides 8 with improved activity against a panel of seven clinically relevant single and double m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecafd765be18915e8beb95c4bf4665d5
https://doi.org/10.1016/j.ejmech.2015.08.007
https://doi.org/10.1016/j.ejmech.2015.08.007
Autor:
Yi-Pei Lu, Fen-Er Chen, Zheng-Yong Wan, Yuan Tao, Xinlong Wang, Christophe Pannecouque, Dirk Daelemans, Jin Yao, Hong Yin, Yan Wu, Erik De Clercq, Tian-Qi Mao, Haifeng Wang
Publikováno v:
European Journal of Medicinal Chemistry. 97:1-9
A novel series of piperidin-4-yl-aminopyrimidine derivatives were designed fusing the pharmacophore templates of etravirine–VRX-480773 hybrids our group previously described and piperidine-linked aminopyrimidines. Most compounds displayed significa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45138ae975f34269891fc3924475ea77
https://doi.org/10.1016/j.ejmech.2015.04.050
https://doi.org/10.1016/j.ejmech.2015.04.050
Publikováno v:
Proceedings, Vol 1, Iss 6, p 274 (2017)
Reverse transcriptase (RT), the key enzyme in the HIV life cycle of HIV, is one of the main targets for the antiretroviral chemotherapy. [...]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bb733abcab653442685aedaf8db2f13
https://www.mdpi.com/2504-3900/1/6/274
https://www.mdpi.com/2504-3900/1/6/274
Autor:
Dirk Daelemans, Hu-Ri Piao, Tian-Qi Mao, Fen-Er Chen, Zheng-Yong Wan, Hong Yin, Ya-Feng Wang, Yuan Tao, Christophe Pannecouque, Erik De Clercq
Publikováno v:
Bioorganicmedicinal chemistry. 23(15)
A novel series of etravirine-VRX-480773 hybrids were designed using structure-guided molecular hybridization strategy and fusing the pharmacophore templates of etravirine and VRX-480773. The anti-HIV-1 activity and cytotoxicity was evaluated in MT-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1eb762fac8575e29f63e7e4799b79c6
https://pubmed.ncbi.nlm.nih.gov/26162497
https://pubmed.ncbi.nlm.nih.gov/26162497
Autor:
Zheng-Yong Wan, Wen-Xue Chen, Tian-Qi Mao, Erik De Clercq, Fen-Er Chen, Gang-Feng Tang, Christophe Pannecouque, Dirk Daelemans, Qiu-Qin He
Publikováno v:
Bioorganicmedicinal chemistry. 23(13)
A molecular hybridization approach is a powerful tool in the design of new molecules with improved affinity and efficacy. In this context, a series of diarylpyrimidine–quinolone hybrids were synthesized and evaluated against both wt HIV-1 and mutan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43922516645b3838468aef8c2d964ea1
https://pubmed.ncbi.nlm.nih.gov/25907370
https://pubmed.ncbi.nlm.nih.gov/25907370
Autor:
Kai-Yan Zang, Er-Tao Hu, Zheng-Yong Wang, Hua-Tian Tu, Yu-Xiang Zheng, Song-You Wang, Hai-Bin Zhao, Yue-Mei Yang, Young-Pak Lee, Liang-Yao Chen
Publikováno v:
Crystals, Vol 10, Iss 7, p 552 (2020)
In this work, we present a simple method to improve the thermoelectric performance of the RF sputtered bismuth telluride films by raising the power of deposition. The as-deposited samples synthesized under different powers were investigated and compa
Externí odkaz:
https://doaj.org/article/dace79e91eb346c0803c5dbb803f437e