Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Zheng-Yin Pan"'
Publikováno v:
Inorganic Chemistry Frontiers. 10:3284-3292
Ir3 is reported to photodegrade CAIX under hypoxia, which improve the cancer immune microenvironment, and induce immunogenic pyroptosis through lipid peroxidation under hypoxia.
Publikováno v:
Dalton Transactions. 52:1291-1300
A near-infrared Ir(iii) complex with aggregation-induced emission (AIE) properties exhibits potent photodynamic anticancer activity in vitro and in vivo upon 525 nm light irradiation.
Publikováno v:
Journal of Medicinal Chemistry. 65:14692-14700
Publikováno v:
Chemical Communications. 58:8069-8072
A binding-enhanced ruthenium-based photosensitizer is reported for photodegradation of carbonic anhydrase IX.
Publikováno v:
Dalton Transactions.
Two new β-carboline copper(ii) complexes bind to DNA by insertion and induce apoptosis associated with mitochondrial damage and oxidative stress.
Publikováno v:
Journal of medicinal chemistry. 65(21)
DNA damage repair is considered to be an important mechanism of cisplatin resistance, and the roles of iron homeostasis in action mechanisms of cisplatin have not been studied yet. Herein, a Pt(IV) prodrug (
Publikováno v:
Chemical communications (Cambridge, England). 58(58)
Carbonic anhydrase IX (CAIX) is overexpressed in many cancer types. Herein, a CAIX targeting and binding-enhanced ruthenium-based photodegrader, Ru-dppz-CAi, is constructed by conjugating the photosensitizer with the inhibiting group
Publikováno v:
Chemical science. 13(38)
Regulation of tumor hypoxia and redox homeostasis is a promising strategy for cancer therapy. Nanocatalytic medicine has played more and more important roles in this field because it can cleverly convert the efficiency and selectivity of catalysis in
Publikováno v:
Dyes and Pigments. 211:111077
Publikováno v:
ACS Applied Materials & Interfaces. 12:43444-43455
Cisplatin resistance in tumor cells is known mainly due to the reduced accumulation of platinum ions by efflux, detoxification by intracellular GSH, and nucleotide excision repair machinery-mediated nuclear DNA repair. In this work, theranostic Pt(IV