Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Zheng-Li Shi"'
Autor:
Jun-Yu Si, Yuan-Mei Chen, Ye-Hui Sun, Meng-Xue Gu, Mei-Ling Huang, Lu-Lu Shi, Xiao Yu, Xiao Yang, Qing Xiong, Cheng-Bao Ma, Peng Liu, Zheng-Li Shi, Huan Yan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Our comprehensive understanding of the multi-species ACE2 adaptiveness of sarbecoviruses remains elusive, particularly for those with various receptor binding motif (RBM) insertions/deletions (indels). Here, we analyzed RBM sequences from 26
Externí odkaz:
https://doaj.org/article/c0451fb881324c9f9837a98fa34e1afa
Autor:
Xian Li, Mengxin Xu, Jingyi Yang, Li Zhou, Lin Liu, Min Li, Shasha Wang, Mei-Qin Liu, Zhixiang Huang, Zhen Zhang, Shuning Liu, Yunqi Hu, Haofeng Lin, Bowen Liu, Ying Sun, Qingguo Wu, Zheng-Li Shi, Ke Lan, Yu Chen, Huimin Yan, Yao-Qing Chen
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-12 (2024)
Abstract Developing a mucosal vaccine against SARS-CoV-2 is critical for combatting the epidemic. Here, we investigated long-term immune responses and protection against SARS-CoV-2 for the intranasal vaccination of a triple receptor-binding domain (R
Externí odkaz:
https://doaj.org/article/b7066e2f718942a8a2557676dfdd8e3a
Autor:
Daxi Wang, Xinglou Yang, Zirui Ren, Ben Hu, Hailong Zhao, Kaixin Yang, Peibo Shi, Zhipeng Zhang, Qikai Feng, Carol Vannesa Nawenja, Vincent Obanda, Kityo Robert, Betty Nalikka, Cecilia Njeri Waruhiu, Griphin Ochieng Ochola, Samson Omondi Onyuok, Harold Ochieng, Bei Li, Yan Zhu, Haorui Si, Jiefang Yin, Karsten Kristiansen, Xin Jin, Xun Xu, Minfeng Xiao, Bernard Agwanda, Sheila Ommeh, Junhua Li, Zheng-Li Shi
Publikováno v:
Microbiome, Vol 12, Iss 1, Pp 1-17 (2024)
Abstract Background Zoonotic viruses cause substantial public health and socioeconomic problems worldwide. Understanding how viruses evolve and spread within and among wildlife species is a critical step when aiming for proactive identification of vi
Externí odkaz:
https://doaj.org/article/07dfbd67964d46dd9036aee1887f27a3
Autor:
Zhen Zhang, Li Zhou, Qianyun Liu, Yucheng Zheng, Xue Tan, Zhixiang Huang, Ming Guo, Xin Wang, Xianying Chen, Simeng Liang, Wenkang Li, Kun Song, Kun Yan, Jiali Li, Qiaohong Li, Yuzhen Zhang, Shimin Yang, Zeng Cai, Ming Dai, Qiaoyang Xian, Zheng-Li Shi, Ke Xu, Ke Lan, Yu Chen
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
ABSTRACTAnimal models of COVID-19 facilitate the development of vaccines and antivirals against SARS-CoV-2. The efficacy of antivirals or vaccines may differ in different animal models with varied degrees of disease. Here, we introduce a mouse model
Externí odkaz:
https://doaj.org/article/fa17329035b44d72b792b36985b71803
Deep spatial proteomics reveals region-specific features of severe COVID-19-related pulmonary injury
Autor:
Yiheng Mao, Ying Chen, Yuan Li, Longda Ma, Xi Wang, Qi Wang, An He, Xi Liu, Tianyi Dong, Weina Gao, Yanfen Xu, Liang Liu, Liang Ren, Qian Liu, Peng Zhou, Ben Hu, Yiwu Zhou, Ruijun Tian, Zheng-Li Shi
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113689- (2024)
Summary: As a primary target of severe acute respiratory syndrome coronavirus 2, lung exhibits heterogeneous histopathological changes following infection. However, comprehensive insight into their protein basis with spatial resolution remains defici
Externí odkaz:
https://doaj.org/article/76942804dfce4a368f00f612d0b5cfed
Autor:
Yu-Lin Yao, Yun Luo, Qi Wang, Rong Geng, Ying Chen, Mei-Qin Liu, Bei Li, Jing Chen, Chun-Guang Wu, Jing-Kun Jia, Jing-Yi Luo, Yan-Tong He, Ting-Ting Jiang, Yan Zhu, Ben Hu, Peng Zhou, Zheng-Li Shi
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 2 (2023)
Zoonotic transmission of coronaviruses (CoVs) poses a serious public health threat. Swine acute diarrhea syndrome coronavirus (SADS-CoV), originating from a bat HKU2-related CoV, causes devastating swine diseases and poses a high risk of spillover to
Externí odkaz:
https://doaj.org/article/4a79bc04a2ae4817937a82ab1e78f5aa
Autor:
Xiao-Shuang Zheng, Qi Wang, Ting-ting Xie, Hao-rui Si, Wei Zhang, Yan Zhu, Ang Li, Jia Su, Zheng-Li Shi, Peng Zhou
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 2 (2023)
Zoonotic coronaviruses (CoVs) caused major human outbreaks in the last two decades. One of the biggest challenges during future CoV disease is ensuring rapid detection and diagnosis at the early phase of a zoonotic event, and active surveillance to t
Externí odkaz:
https://doaj.org/article/a2fc695fedee41abaa4d771336f5b768
Autor:
Yang Li, Xi Wang, Xu-Rui Shen, Rong Geng, Nan Xie, Jun-Feng Han, Qing-Miao Zhang, Zheng-Li Shi, Peng Zhou
Publikováno v:
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 902-913 (2022)
The immune memory of over 400 million COVID-19 convalescents is not completely understood. In this integrated study, we recorded the post-acute sequelae symptoms and tested the immune memories, including circulating antibodies, memory B cell, and mem
Externí odkaz:
https://doaj.org/article/6b60a4ead20f4ec2af58a42b046080c6
Autor:
Jingyi Yang, Mei-Qin Liu, Lin Liu, Xian Li, Mengxin Xu, Haofeng Lin, Min Li, Huimin Yan, Yao-Qing Chen, Zheng-Li Shi
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/064d9a79b51449928ddba45272ead7b8
Autor:
Cecilia A. Sánchez, Hongying Li, Kendra L. Phelps, Carlos Zambrana-Torrelio, Lin-Fa Wang, Peng Zhou, Zheng-Li Shi, Kevin J. Olival, Peter Daszak
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Coronaviruses may spill over from bats to humans. This study uses epidemiological data, species distribution models, and probabilistic risk assessment to map overlap among people and SARSr-CoV bat hosts and estimate how many people are infected with
Externí odkaz:
https://doaj.org/article/66255a7e62a7427e8eae4ef6be146421