Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Zheng-Hai Tang"'
Publikováno v:
Redox Biology, Vol 12, Iss , Pp 367-376 (2017)
Chelerythrine (CHE), a natural benzo[c]phenanthridine alkaloid, shows anti-cancer effect through a number of mechanisms. Herein, the effect and mechanism of the CHE-induced autophagy, a type II programmed cell death, in non-small cell lung cancer (NS
Externí odkaz:
https://doaj.org/article/cbf5db40e1594a1f805fd684f772449d
Autor:
YA-FANG WANG1, ZHENG-HAI TANG1, TING LI1, XIAO-HUANG XU1, XIUPING CHEN1, YING WANG1, YI-TAO WANG1, JIN-JIAN LU1 jinjian.lu@163.com
Publikováno v:
Molecular Medicine Reports. Dec2017, Vol. 16 Issue 6, p8392-8398. 7p.
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 18:550-555
Background: Osimertinib (OSI), also known as AZD9291, is a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) that has been approved for the treatment of non-small cell lung cancer (NSCLC) patients. Objective: Es
Autor:
Zheng-Hai Tang, Jin-Jian Lu
Publikováno v:
Cancer Letters. 420:242-246
Given the successful identification of epidermal growth factor receptor EGFR T790M, the third-generation EGFR tyrosine kinase inhibitor (TKI), osimertinib (OSI, AZD9291), was developed to target EGFR T790M mutation. OSI was approved for the treatment
Autor:
Ying Wang, Xiao-Huang Xu, Yitao Wang, Xiuping Chen, Ting Li, Ya-Fang Wang, Jin-Jian Lu, Zheng-Hai Tang
Publikováno v:
Molecular Medicine Reports. 16:8392-8398
Baicalein (BA), one of the major bioactive flavonoids isolated from Scutellariae Radix, possesses various pharmacological activities. The present study aimed to investigate the protective effects of BA on tert‑butyl hydroperoxide (t‑BHP)‑induce
Publikováno v:
RSC Advances. 7:42597-42605
Autophagy, an evolutionarily conserved cellular self-digestive process, is associated with different diseases and can be inhibited or induced by a series of agents. In this study, we reported that fangchinoline (FCL), an alkaloid from Stephania tetra
Autor:
Ya-Fang Wang, Jin-Jian Lu, Dik-Lung Ma, Yu Lian Xu, Wenan Qiang, Ting Li, Yitao Wang, Jia-Hong Lu, Xiuping Chen, Chung-Hang Leung, Le Le Zhang, Zheng-Hai Tang
Publikováno v:
The American Journal of Chinese Medicine. 45:123-136
Baicalein (BA), one of the major compounds isolated from the root of Scutellaria baicalensis Gerogi, exhibits various pharmacological effects, such as anti-oxidant, anti-inflammatory, and anticancer effects. In this study, we found that BA reduced ce
Publikováno v:
Oncotarget
// Zheng-Hai Tang 1, * , Xiao-Ming Jiang 1, * , Xia Guo 1 , Chi Man Vivienne Fong 1 , Xiuping Chen 1 , Jin-Jian Lu 1 1 State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, Ch
Autor:
Xiuping Chen, Xin Chen, Yitao Wang, Chun-Yong Ding, Jin-Jian Lu, Yu-Lian Xu, Ting Li, Xiao-Huang Xu, Xiao-Feng Yuan, Le-Le Zhang, Mingqing Huang, Zheng-Hai Tang
Publikováno v:
Phytomedicine. 23:800-809
Background Ovarian cancer is the first leading cause of death among gynecologic malignancies worldwide. Discovery of new chemotherapeutic drugs is still imperative for the improvement of the survival rate. Purpose This study aims to investigate the a
Publikováno v:
The American Journal of Chinese Medicine. 44:197-226
Carthamus tinctorius L. is a multifunctional cash crop. Its flowers and seeds are extensively used in traditional herbal medicine in China, Korea, Japan, and other Asian countries, for treating various ailments such as gynecological, cardiovascular,