Výsledky vyhledávání - "Zheng Xiufen"

Akademický článek

Gene silencing of IL-12 in dendritic cells inhibits autoimmune arthritis

Autor: Li Rong, Zheng Xiufen, Popov Igor, Zhang Xusheng, Wang Hongmei, Suzuki Motohiko, De Necochea-Campion Rosalia, French Peter W, Chen Di, Siu Leo, Koos David, Inman Robert D, Min Wei-Ping

Publikováno v: Journal of Translational Medicine, Vol 10, Iss 1, p 19 (2012)

Abstract Background We have previously demonstrated that immune modulation can be accomplished by administration of gene silenced dendritic cells (DC) using siRNA. In this study, we demonstrate the therapeutic utilization of shRNA-modified DC as an a

Externí odkaz: https://doaj.org/article/b0657d987d9d4a9db5b14b6cd4948c31

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Akademický článek

Preventing intimal thickening of vein grafts in vein artery bypass using STAT-3 siRNA

Autor: Sun Jiangbin, Zheng Jinhua, Ling Kaitelynne H, Zhao Keyan, Xie Zhongshang, Li Bo, Wang Tiance, Zhu Zhicheng, Patel Amit N, Min Weiping, Liu Kexiang, Zheng Xiufen

Publikováno v: Journal of Translational Medicine, Vol 10, Iss 1, p 2 (2012)

Abstract Background Proliferation and migration of vascular smooth muscle cells (VSMCs) play a key role in neointimal formation which leads to restenosis of vein graft in venous bypass. STAT-3 is a transcription factor associated with cell proliferat

Externí odkaz: https://doaj.org/article/36ca67c9b84645168dce3895bbbef061

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Akademický článek

Prevention of hyperglycemia-induced myocardial apoptosis by gene silencing of Toll-like receptor-4

Autor: Singh Manpreet, Shunnar Aminah, Lai Xiaoyan, Cheng Xiaoshu, Jiang Nan, Zhang Xusheng, Zheng Xiufen, Zhu Huaqing, Peng Tianqing, Zhang Yuwei, Riordan Neil, Bogin Vladimir, Tong Nanwei, Min Wei-Ping

Publikováno v: Journal of Translational Medicine, Vol 8, Iss 1, p 133 (2010)

Abstract Background Apoptosis is an early event involved in cardiomyopathy associated with diabetes mellitus. Toll-like receptor (TLR) signaling triggers cell apoptosis through multiple mechanisms. Up-regulation of TLR4 expression has been shown in d

Externí odkaz: https://doaj.org/article/182459406fc7440d936c7dc5310474e3

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Akademický článek

Exosomes as a tumor immune escape mechanism: possible therapeutic implications

Autor: Hanley Harold H, Joyce James A, Hao Xishan, Ren Xiubao, Zheng Xiufen, Kaushal Shalesh, Zhong Zhaohui, Ichim Thomas E, Riordan Neil H, Koropatnick James, Bogin Vladimir, Minev Boris R, Min Wei-Ping, Tullis Richard H

Publikováno v: Journal of Translational Medicine, Vol 6, Iss 1, p 37 (2008)

Abstract Advances in cancer therapy have been substantial in terms of molecular understanding of disease mechanisms, however these advances have not translated into increased survival in the majority of cancer types. One unsolved problem in current c

Externí odkaz: https://doaj.org/article/374d1c5f5a9a4c7fb6220c869bb40709

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