Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Zheng D. Lan"'
Autor:
Hong Seok Shim, James W. Horner, Chang-Jiun Wu, Jiexi Li, Zheng D. Lan, Shan Jiang, Xueping Xu, Wen-Hao Hsu, Tomasz Zal, Ivonne I. Flores, Pingna Deng, Yuan-Ta Lin, Li-Huei Tsai, Y. Alan Wang, Ronald A. DePinho
Publikováno v:
Nat Aging
Amyloid-induced neurodegeneration plays a central role in Alzheimer’s disease (AD) pathogenesis. Here, we show that telomerase reverse transcriptase (TERT) haploinsufficiency decreases BDNF and increases amyloid-β (Aβ) precursor in murine brain.
Autor:
Baoli Hu, Massimo Squatrito, Nikunj Satani, Eskil Eskilsson, Jian Hu, Charles Etienne Gabriel Sauvé, Mitchel S. Berger, Emmanuel Martinez-Ledesma, Roel G.W. Verhaak, Hoon Kim, Amy B. Heimberger, Yan Li, Siyuan Zheng, Konrad Gabrusiewicz, Do Hyun Nam, Joanna J. Phillips, Ronald A. DePinho, Hee Jin Cho, Floris P. Barthel, Edward I. Chang, Gaetano Finocchiaro, Florian L. Muller, Zheng D. Lan, Adriana Olar, Qianghu Wang, Ana C. deCarvalho, Pengping Li, Erik P. Sulman, Tom Mikkelsen, Guocan Wang, Sali Lyu, Yu Hsi Lin, Lisa Scarpace, Xin Hu
Publikováno v:
Cancer cell, vol 32, iss 1
Cancer Cell, 33(1). Cell Press
Wang, Q, Hu, B, Hu, X, Kim, H, Squatrito, M, Scarpace, L, deCarvalho, A C, Lyu, S, Li, P, Li, Y, Barthel, F, Cho, H J, Lin, Y-H, Satani, N, Martinez-Ledesma, E, Zheng, S, Chang, E, Gabriel Sauvé, C-E, Olar, A, Lan, Z D, Finocchiaro, G, Phillips, J J, Berger, M S, Gabrusiewicz, K R, Wang, G, Eskilsson, E, Hu, J, Mikkelsen, T, DePinho, R A, Muller, F, Heimberger, A B, Sulman, E P, Nam, D-H & Verhaak, R G W 2018, ' Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment ', Cancer Cell, vol. 33, no. 1, pp. 152 . https://doi.org/10.1016/j.ccell.2017.12.012
Cancer Cell, 33(1). Cell Press
Wang, Q, Hu, B, Hu, X, Kim, H, Squatrito, M, Scarpace, L, deCarvalho, A C, Lyu, S, Li, P, Li, Y, Barthel, F, Cho, H J, Lin, Y-H, Satani, N, Martinez-Ledesma, E, Zheng, S, Chang, E, Gabriel Sauvé, C-E, Olar, A, Lan, Z D, Finocchiaro, G, Phillips, J J, Berger, M S, Gabrusiewicz, K R, Wang, G, Eskilsson, E, Hu, J, Mikkelsen, T, DePinho, R A, Muller, F, Heimberger, A B, Sulman, E P, Nam, D-H & Verhaak, R G W 2018, ' Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment ', Cancer Cell, vol. 33, no. 1, pp. 152 . https://doi.org/10.1016/j.ccell.2017.12.012
We leveraged IDH wild-type glioblastomas, derivative neurospheres, and single-cell gene expression profiles to define three tumor-intrinsic transcriptional subtypes designated as proneural, mesenchymal, and classical. Transcriptomic subtype multiplic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::711983637204df62607359c64d15d147
https://escholarship.org/uc/item/4h87g798
https://escholarship.org/uc/item/4h87g798
Autor:
Y. Alan Wang, Lynda Chin, Baoli Hu, Derrick Sek Tong Ong, Mitchel S. Berger, Lynda J. Corley, Charles Etienne Gabriel Sauvé, Marta Moreno Monasterio, Erik P. Sulman, Joanna J. Phillips, Yan Wing Ho, Ronald A. DePinho, Haiyan Yan, Linbo Cai, Yi Zhong, Roeland Verhaak, Sujun Hua, Guocan Wang, Zhi Tan, Jian Hu, Xin Lu, Pingna Deng, Yongping You, Denise J. Spring, Wen Ting Liao, Jianhua Zhang, Ning Liu, Qianghu Wang, Junxia Zhang, Qing Chang, Gregory N. Fuller, Gaetano Finocchiaro, Zheng D. Lan
Publikováno v:
Cell, vol 167, iss 5
Glioblastoma stem cells (GSCs) are implicated in tumor neovascularization, invasiveness, and therapeutic resistance. To illuminate mechanisms governing these hallmark features, we developed a de novo glioblastoma multiforme (GBM) model derived from i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba28baa92505421fd7f170171df5b1f
https://escholarship.org/uc/item/34m3w8h2
https://escholarship.org/uc/item/34m3w8h2
Autor:
Rashmi S. Hegde, Zheng D. Lan, Atira Hardiman, Shyra J. Miller, Jianqiang Wu, Jose A. Cancelas, Deanna M. Patmore, Margaret H. Collins, Jennifer J. Kordich, Timothy P. Cripe, Nancy Ratner
Publikováno v:
Oncogene
Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive sarcomas without effective therapeutics. Bioinformatics was used to identify potential therapeutic targets. Paired Box (PAX), Eyes Absent (EYA), Dachsund (DACH) and Sine Oculis (SIX) ge
Autor:
Katheryn Rilea, Akash R. Patel, Zheng D. Lan, William Humphries, Ali Jalali, Bruce L. Ehni, Claudio Esteves Tatsui
Publikováno v:
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. 22(6)
We describe a minimalist approach to perform in situ decompression of the ulnar nerve. Our technique employs a unique small skin incision strategically placed to minimize postoperative scarring over the ulnar nerve and potentially decrease the risk o