Zobrazeno 1 - 10 of 19 pro vyhledávání: '"Zheng‐Yin Pan"'
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Akademický článek
Microtubule polymerization induced by iridium‐fullerene photosensitizers for cancer immunotherapy via dual‐reactive oxygen species regulation strategy
Autor: Xiao‐Xiao Chen, Kun Peng, Xi Chen, Zheng‐Yin Pan, Qing‐Hua Shen, Yu‐Yi Ling, Jian‐Zhang Zhao, Cai‐Ping Tan
Publikováno v: Aggregate, Vol 5, Iss 6, Pp n/a-n/a (2024)
Abstract Microtubules (MTs) are key players in cell division, migration, and signaling, and they are regarded as important targets for cancer treatment. In this work, two fullerene (C60)‐functionalized Ir(III) complexes (Ir‐C601 and Ir‐C602) ar
Externí odkaz: https://doaj.org/article/1e9cb229e7bb48169c680982bced8a8c
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2
Photodegradation of carbonic anhydrase by iridium complexes for induction of immunogenic cell death under hypoxia
Autor: Yu-Yi Ling, Ya-Jie Kong, Liang Hao, Zheng-Yin Pan, Zong-Wan Mao, Cai-Ping Tan
Publikováno v: Inorganic Chemistry Frontiers. 10:3284-3292
Ir3 is reported to photodegrade CAIX under hypoxia, which improve the cancer immune microenvironment, and induce immunogenic pyroptosis through lipid peroxidation under hypoxia.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b74ea3ccdb5325df9763a0bf1f9efd1b
https://doi.org/10.1039/d3qi00376k
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3
Near-infrared AIE-active phosphorescent iridium(iii) complex for mitochondria-targeted photodynamic therapy
Autor: Zheng-Yin Pan, Bin-Fa Liang, Yun-Shi Zhi, Da-Hong Yao, Chen-Yang Li, Hai-Qiang Wu, Liang He
Publikováno v: Dalton Transactions. 52:1291-1300
A near-infrared Ir(iii) complex with aggregation-induced emission (AIE) properties exhibits potent photodynamic anticancer activity in vitro and in vivo upon 525 nm light irradiation.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7e322fab3b82ba368369a4d87e9f9aaf
https://doi.org/10.1039/d2dt03861g
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5
Photodegradation of carbonic anhydrase IX via a binding-enhanced ruthenium-based photosensitizer
Autor: Liang Hao, Jie Wang, Zheng-Yin Pan, Zong-Wan Mao, Cai-Ping Tan
Publikováno v: Chemical Communications. 58:8069-8072
A binding-enhanced ruthenium-based photosensitizer is reported for photodegradation of carbonic anhydrase IX.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1b3b9bbe277b0797e98504528f1f2622
https://doi.org/10.1039/d2cc02337g
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6
Synthesis, characterization and biological activity of novel copper complexes containing a β-carboline derivative and amino acids
Autor: Bai-Hua Chen, Zheng-Yin Pan, Wen-Wen Feng, Qi-Yan Liu, Yingju Liu, Liang He
Publikováno v: Dalton Transactions.
Two new β-carboline copper(ii) complexes bind to DNA by insertion and induce apoptosis associated with mitochondrial damage and oxidative stress.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5062de039f2ac636e8b4a1c4a025e651
https://doi.org/10.1039/d3dt01088k
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7
A platinum-ruthenium hybrid prodrug with multi-enzymatic activities for chemo-catalytic therapy of hypoxic tumors
Autor: Gang-Gang Yang, Xu-Xian Su, Bing-Bing Liang, Zheng-Yin Pan, Qian Cao, Zong-Wan Mao
Publikováno v: Chemical science. 13(38)
Regulation of tumor hypoxia and redox homeostasis is a promising strategy for cancer therapy. Nanocatalytic medicine has played more and more important roles in this field because it can cleverly convert the efficiency and selectivity of catalysis in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac5eb9c06db5ef9e01426d59cca1661
https://pubmed.ncbi.nlm.nih.gov/36320579
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8
Precisely Assembled Nanoparticles against Cisplatin Resistance via Cancer-Specific Targeting of Mitochondria and Imaging-Guided Chemo-Photothermal Therapy
Autor: Gang-Gang Yang, Dong-Yang Zhang, Zong-Wan Mao, Zheng-Yin Pan, Liang-Nian Ji, Qian Cao
Publikováno v: ACS Applied Materials & Interfaces. 12:43444-43455
Cisplatin resistance in tumor cells is known mainly due to the reduced accumulation of platinum ions by efflux, detoxification by intracellular GSH, and nucleotide excision repair machinery-mediated nuclear DNA repair. In this work, theranostic Pt(IV
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::230b398cec04389378341ecc319151a7
https://doi.org/10.1021/acsami.0c12814
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9
Recoding the Cancer Epigenome by Intervening in Metabolism and Iron Homeostasis with Mitochondria‐Targeted Rhenium(I) Complexes
Autor: Hang Zhang, Liang Hao, Lu-Si Rao, Cai-Ping Tan, Zheng-Yin Pan, Zong-Wan Mao, Yue Zheng, Liang-Nian Ji
Publikováno v: Angewandte Chemie International Edition. 59:18755-18762
The development and malignancy of cancer cells are closely related to the changes of the epigenome. In this work, a mitochondria-targeted rhenium(I) complex (DFX-Re3), integrating the clinical iron chelating agent deferasirox (DFX), has been designed
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196f61ac536b5200be9b7e122e10a423
https://doi.org/10.1002/anie.202008624
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