ALK upregulates POSTN and WNT signaling to drive neuroblastoma

Autor: Huang, Miller, Fang, Wanqi, Farrel, Alvin, Li, Linwei, Chronopoulos, Antonios, Nasholm, Nicole, Cheng, Bo, Zheng, Tina, Yoda, Hiroyuki, Barata, Megumi J., Porras, Tania, Miller, Matthew L., Zhen, Qiqi, Ghiglieri, Lisa, McHenry, Lauren, Wang, Linyu, Asgharzadeh, Shahab, Park, JinSeok, Gustafson, W. Clay, Matthay, Katherine K., Maris, John M., Weiss, William A.

Publikováno v: In Cell Reports 26 March 2024 43(3)

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Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis

Autor: Huang, Miller, Tailor, Jignesh, Zhen, Qiqi, Gillmor, Aaron H, Miller, Matthew L, Weishaupt, Holger, Chen, Justin, Zheng, Tina, Nash, Emily K, McHenry, Lauren K, An, Zhenyi, Ye, Fubaiyang, Takashima, Yasuhiro, Clarke, James, Ayetey, Harold, Cavalli, Florence MG, Luu, Betty, Moriarity, Branden S, Ilkhanizadeh, Shirin, Chavez, Lukas, Yu, Chunying, Kurian, Kathreena M, Magnaldo, Thierry, Sevenet, Nicolas, Koch, Philipp, Pollard, Steven M, Dirks, Peter, Snyder, Michael P, Largaespada, David A, Cho, Yoon Jae, Phillips, Joanna J, Swartling, Fredrik J, Morrissy, A Sorana, Kool, Marcel, Pfister, Stefan M, Taylor, Michael D, Smith, Austin, Weiss, William A

Publikováno v: Cell stem cell, vol 25, iss 3
Huang, M, Tailor, J, Zhen, Q, Gillmor, A H, Miller, M L, Weishaupt, H, Chen, J, Zheng, T, Nash, E K, McHenry, L K, An, Z, Ye, F, Takashima, Y, Clarke, J, Ayetey, H, Cavalli, F M G, Luu, B, Moriarity, B S, Ilkhanizadeh, S, Chavez, L, Yu, C, Kurian, K M, Magnaldo, T, Sevenet, N, Koch, P, Pollard, S M, Dirks, P, Snyder, M P, Largaespada, D A, Cho, Y J, Phillips, J J, Swartling, F J, Morrissy, A S, Kool, M, Pfister, S M, Taylor, M D, Smith, A & Weiss, W A 2019, ' Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis ', Cell Stem Cell, vol. 25, no. 3, pp. 433-446.e7 . https://doi.org/10.1016/j.stem.2019.05.013
Cell stem cell

SUMMARY Human neural stem cell cultures provide progenitor cells that are potential cells of origin for brain cancers. However, the extent to which genetic predisposition to tumor formation can be faithfully captured in stem cell lines is uncertain.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a7a8581193724542cbe0a79f70f842
https://www.repository.cam.ac.uk/handle/1810/294953

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