FoxO1 interacts with transcription factor EB and differentially regulates mitochondrial uncoupling proteins via autophagy in Adipocytes

Autor: Liu, Longhua, Tao, Zhipeng, Zheng, Louise D., Brooke, Joseph P., Smith, Cayleen M., Liu, Dongmin, Long, Yun Chau, Cheng, Zhiyong

Mitochondrial uncoupling proteins (UCPs) are inducible and play an important role in metabolic and redox homeostasis. Recent studies have suggested that FoxO1 controls mitochondrial biogenesis and morphology, but it remains largely unknown how FoxO1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2485::f3b8ecb27024a0f22b856112c9035a9e
https://hdl.handle.net/10919/76692

Clinical Epigenetics

Autor: Zheng, Louise D., Linarelli, Leah E., Liu, Longhua, Wall, Sarah S., Greenawald, Mark H., Seidel, Richard W., Estabrooks, Paul A., Almeida, Fabio A., Cheng, Zhiyong

Background Mitochondrial alterations have been observed in subjects with metabolic disorders such as obesity and diabetes. Studies on animal models and cell cultures suggest aberrant glucose and lipid levels, and impaired insulin signaling might lead

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a449878e737138d54aedef1c3bcf9bf3
https://hdl.handle.net/10919/55024

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Mitochondrial epigenetic changes and progression from metabolically healthy obesity to metabolically unhealthy obesity: a cross-sectional study

Autor: Zheng, Louise D, Brooke, Joseph, Smith, Cayleen, Almeida, Fabio A, Cheng, Zhiyong

Publikováno v: In The Lancet Diabetes & Endocrinology November 2016 4 Supplement 1:S16-S16

Autophagy in Adipocyte Differentiation.

Autor: Tao Z; Department of Human Nutrition, Foods, and Exercise, Fralin Translational Obesity Research Center, College of Agriculture and Life Science, Virginia Tech, 1981 Kraft Drive, Blacksburg, VA, 24061, USA., Liu L; Department of Human Nutrition, Foods, and Exercise, Fralin Translational Obesity Research Center, College of Agriculture and Life Science, Virginia Tech, 1981 Kraft Drive, Blacksburg, VA, 24061, USA.; Department of Pathology and Cell Biology, Naomi Berrie Diabetes Center, College of Physicians and Surgeons, Columbia University, Virginia Tech, 1981 Kraft Drive, New York, NY 10032, USA., Zheng LD; Department of Human Nutrition, Foods, and Exercise, Fralin Translational Obesity Research Center, College of Agriculture and Life Science, Virginia Tech, 1981 Kraft Drive, Blacksburg, VA, 24061, USA., Cheng Z; Department of Human Nutrition, Foods, and Exercise, Fralin Translational Obesity Research Center, College of Agriculture and Life Science, Virginia Tech, 1981 Kraft Drive, Blacksburg, VA, 24061, USA. zcheng@vt.edu.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2019; Vol. 1854, pp. 45-53.