Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Zhenfu, Fu"'
Publikováno v:
Molecules, Vol 28, Iss 4, p 1829 (2023)
The protein PARP1, which plays a crucial role in DNA repair processes, is an attractive target for cancer therapy, especially for BRCA-deficient cancers. To overcome the acquired drug resistance of PARP1, PARP1 G-quadruplex (G4) identified in the PAR
Externí odkaz:
https://doaj.org/article/bd9646b798f44801b29f1098afe6ae2f
Autor:
Ying Chen, Tieming Xie, Zhimin Ye, Fangzheng Wang, Dan Long, Mingxiang Jiang, Jun Fang, Qingren Lin, Kai Li, Zhun Wang, Zhenfu Fu
Publikováno v:
Radiation Oncology, Vol 14, Iss 1, Pp 1-9 (2019)
Abstract Aims To determine the biological correlation between apparent diffusion coefficient (ADC) values and Sirtuin1 (SIRT1) levels of tumour tissues in patients with esophageal carcinoma (EC), and to ascertain the treatment biomarker of ADC in pre
Externí odkaz:
https://doaj.org/article/bc9822eacb9b41eca3b7e8ef2e9208cc
Autor:
Zhimin Ye, Fangzheng Wang, Fengqin Yan, Lei Wang, Bin Li, Tongxin Liu, Fujun Hu, Mingxiang Jiang, Weiyang Li, Zhenfu Fu
Publikováno v:
World Journal of Surgical Oncology, Vol 17, Iss 1, Pp 1-10 (2019)
Abstract Background The incidence of nasopharyngeal carcinoma (NPC) is rare, but a certain amount of mortality remains in NPC patients. Our study aimed to identify candidate genes as biomarkers for NPC screening, diagnosis, and therapy. Methods We in
Externí odkaz:
https://doaj.org/article/37f99126ceb24dc9928eee90fbb96db4
Autor:
Fangzheng Wang, Chuner Jiang, Zhiming Ye, Quanquan Sun, Tongxin Liu, Min Xu, Peng Wu, Kaiyuan Shi, Bin Long, Zhenfu Fu, Yangming Jiang
Publikováno v:
Translational Oncology, Vol 11, Iss 2, Pp 338-345 (2018)
OBJECTIVE: This study was conducted to assess the efficacy and safety of nimotuzumab combined with radiotherapy (RT) in elderly patients with nasopharyngeal carcinoma. MATERIALS AND METHODS: The clinical data of 75 nasopharyngeal carcinoma patients,
Externí odkaz:
https://doaj.org/article/9bb83ecb6b9c49a0b8ed7e014491ad8b
Autor:
Fangzheng Wang, Chuner Jiang, Zhimin Ye, Tongxin Liu, Quanquan Sun, Fengqin Yan, Weifeng Qin, Zhenfu Fu, Yangming Jiang
Publikováno v:
Translational Oncology, Vol 11, Iss 1, Pp 65-73 (2018)
OBJECTIVES: To report the long-term outcome and toxicity of locoregionally advanced nasopharyngeal carcinoma (LA NPC) treated with nimotuzumab (h-R3) plus intensity-modulated radiotherapy (IMRT) with or without chemotherapy. METHODS: From May 2008 to
Externí odkaz:
https://doaj.org/article/e99478b8aba342ca8f2c787ec5d67463
Autor:
Lei Wang, Fujun Hu, Zhenfu Fu, Fangzheng Wang, Tieming Xie, Fengqin Yan, Jun Fang, Zhimin Ye, Zhun Wang
Publikováno v:
International Journal of Radiation Biology. 97:452-463
Radiotherapy is an effective treatment for esophageal squamous cell carcinoma (ESCC). However, many ESCC patients relapsed after receiving radiotherapy due to the inherent resistance. The function of miR-34a and SIRT1, as well as the correlation betw
Autor:
Fangzheng Wang, Zhenfu Fu, Yuezhen Wang, Zhimin Ye, Fengqin Yan, Jun Fang, Zhun Wang, Tieming Xie, Jianfeng Hua, Lei Wang
Publikováno v:
Translational Cancer Research
Background Esophageal carcinoma (EC) is one of the most deadly malignant tumors in the world. Surgery, combined with chemotherapy or radiotherapy, is the traditional strategy for the treatment of EC. Cisplatin (CDDP) is a common chemotherapy drug wid
Autor:
Lei Wang, Fangzheng Wang, Jiping Liu, Min Xu, Yongfeng Piao, Zhimin Ye, Yangming Jiang, Zhenfu Fu, Fengqin Yan, Chuner Jiang
Publikováno v:
Journal of Cancer
Background and Objectives: Although intensity-modulated radiotherapy (IMRT) provides promising survival advantages and fewer late complications in patients with nasopharyngeal cancer (NPC), appropriated target volumes and prescribed doses are still b
Autor:
Yuezhen Wang, Yongfeng Piao, Zhenfu Fu, Zhimin Ye, Yangming Jiang, Chuner Jiang, Haitao Jiang, Fangzheng Wang, Fengqin Yan
Publikováno v:
Journal of Cancer
Purpose: Currently, the optimal treatment regimens for older nasopharyngeal carcinoma (NPC) patients remained unclear. The aim of this retrospective study is to investigate therapeutic patterns and survival outcomes for a cohort of older NPC patients
Autor:
Zhun Wang, Zhenfu Fu, Zhimin Ye, Yuezhen Wang, Lei Wang, Fangzheng Wang, Jun Fang, Jianfeng Hua, Bin Li, Tongxin Liu
Publikováno v:
Bioscience Reports
Esophageal squamous cell carcinoma (ESCC) is a 5-year survival rate unsatisfied malignancies. The study aimed to identify the novel diagnostic and prognostic targets for ESCC. Expression profiling (GSE89102, GSE97051, and GSE59973) data were download