Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Zhenfang Yan"'
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract Interferon (IFN)-γ inducible protein 16 (IFI16), a key DNA sensor, triggers downstream STING-dependent type I interferon (IFN-I) production and antiviral immunity. However, how the IFI16-STING signaling pathway is regulated by EMCV infectio
Externí odkaz:
https://doaj.org/article/ea256fe9d7064febb7e8adc4c1a9db1c
Autor:
Zhenfang Yan, Jingying Xie, Zhengyang Hou, Yaxin Zhang, Jiayu Yue, Xiangbo Zhang, Lei Chen, Yanmei Yang, Xiangrong Li, Huixia Li, Ruofei Feng
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-12 (2024)
Abstract Natural immunity is the first defense line of the host immune system, which plays a significant role in combating foreign pathogenic microorganisms. The IFN-β (interferon-beta) signaling pathway, being a typical example of innate immunity,
Externí odkaz:
https://doaj.org/article/5e46383ca2b24e3e97117213ec008fae
Autor:
Dianyu Li, Rongqian Mo, Xiaoyi Li, Rongrong Cheng, Jingying Xie, Hongshan Li, Yanmei Yang, Shasha Li, Huixia Li, Zhenfang Yan, Suocheng Wei, Adi Idris, Xiangrong Li, Ruofei Feng
Publikováno v:
mSphere, Vol 9, Iss 6 (2024)
ABSTRACT Mammalian orthoreovirus (MRV) outer capsid protein σ3 is a multifunctional protein containing a double-stranded RNA-binding domain, which facilitates viral entry and assembly. We reasoned that σ3 has an innate immune evasion function. Here
Externí odkaz:
https://doaj.org/article/18e7e51c893543eebec534368e53054e
Autor:
Xu Zhao, Zhengyang Hou, Yaxin Zhang, Daoqin Mao, Zhenfang Yan, Shunyu Yang, Jingying Xie, Ruofei Feng
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 7, p 273 (2024)
Background: Understanding the mechanisms through which interferon (IFN) signaling is negatively regulated is crucial for preserving the equilibrium of innate immune reactions, as the innate immune system functions, such as the original barrier, comba
Externí odkaz:
https://doaj.org/article/6ffc49143f8946119615a7922513c50e
Autor:
Jingying Xie, Xiangrong Li, Shunyu Yang, Zhenfang Yan, Lei Chen, Yanmei Yang, Dianyu Li, Xiangbo Zhang, Ruofei Feng
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Pseudorabies virus (PRV) is an agent of Aujeszky's disease, and causes great economic losses to pig farming. Re-outburst of pseudorabies implies that new control measures are urgently needed. We show here that DDX56 possesses the ability to inhibit P
Externí odkaz:
https://doaj.org/article/3c607773f8d74ade8e85e50ac67c6916
Autor:
Lei Chen, Xiangrong Li, Yingying Deng, Yingjie Bi, Zhenfang Yan, Yanmei Yang, Xiangbo Zhang, Huixia Li, Jingying Xie, Ruofei Feng
Publikováno v:
Viruses, Vol 15, Iss 4, p 866 (2023)
Interferon (IFN) helps cells fight viral infections by further inducing the expression of many downstream IFN-stimulated genes (ISGs). Human interferon-inducible transmembrane proteins (IFITM) are one of these ISGs. The antiviral function of human IF
Externí odkaz:
https://doaj.org/article/4c668a4184e045c080d75819bd65a123
Autor:
Xiangrong Li, Jingying Xie, Dianyu Li, Hongshan Li, Yuhui Niu, Bei Wu, Yanmei Yang, Zhenfang Yan, Xiangbo Zhang, Lei Chen, Ruofei Feng
Publikováno v:
Viruses, Vol 14, Iss 9, p 1851 (2022)
Pseudorabies (PR) is a domestic and wild animal infectious disease caused by the pseudorabies virus (PRV) and is one of the major infectious diseases that endanger the global swine industry. Studies have reported that PRV may achieve cross-species tr
Externí odkaz:
https://doaj.org/article/0f087a2d246740c3aa53afcf116a2258
Publikováno v:
Viruses, Vol 14, Iss 5, p 954 (2022)
Nuclear factor κB (NF-κB) is involved in a wide range of innate immune activities in host cells and serves as an important component of a host’s immunity system. To survive in infected cells, viruses have evolved intricate strategies to evade the
Externí odkaz:
https://doaj.org/article/278d64b745ae41c0b5db57e28ef32086
Autor:
Zhenfang Yan, Jiayu Yue, Yaxin Zhang, Zhengyang Hou, Dianyu Li, Yanmei Yang, Xiangrong Li, Idris, Adi, Huixia Li, Shasha Li, Jingying Xie, Ruofei Feng
Publikováno v:
Virologica Sinica (16740769); Aug2024, Vol. 39 Issue 4, p587-599, 13p