Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Zhenbin Cai"'
Autor:
Jie Yang, Yunlong Zhang, Zhenbin Cai, Jianyu Zou, Shaojin Li, Guiqiang Miao, Hongsheng Lin, Xiaodong Zhao, Minghui Tan
Publikováno v:
Brain Research Bulletin, Vol 205, Iss , Pp 110806- (2023)
Promoting axonal regeneration is an effective strategy for recovery from traumatic spinal cord injury (SCI). Spastin, a microtubule-severing protein, modulates axonal outgrowth and branch formation by regulating microtubule dynamics. However, the exa
Externí odkaz:
https://doaj.org/article/fc61acd6f9de4433a6ec1490d9fd52fc
Autor:
Jianyu Zou, Huihuang Chen, Cuiqing Liu, Zhenbin Cai, Jie Yang, Yunlong Zhang, Shaojin Li, Hongsheng Lin, Minghui Tan
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
BackgroundIntracerebral hemorrhage (ICH) is a stroke syndrome with an unfavorable prognosis. Currently, there is no comprehensive clinical indicator for mortality prediction of ICH patients. The purpose of our study was to construct and evaluate a no
Externí odkaz:
https://doaj.org/article/6ace9d58983d493fb8af6b66a5663b08
Autor:
Jianyu Zou, Zhenbin Cai, Zhi Liang, Yaozhong Liang, Guowei Zhang, Jie Yang, Yunlong Zhang, Hongsheng Lin, Minghui Tan
Publikováno v:
European Journal of Histochemistry, Vol 65, Iss 4 (2021)
Spastin is one of the proteins which lead to hereditary spastic paraplegia (HSP), whose dysfunction towards microtubule severing and membrane transporting is critically important. The present study is to elucidate the mechanisms of the protein stabil
Externí odkaz:
https://doaj.org/article/05b70c61071a4ae1bea48f9d45e59ce3
Autor:
Tao Jiang, Zhenbin Cai, Zhisheng Ji, Jianyu Zou, Zhi Liang, Guowei Zhang, Yaozhong Liang, Hongsheng Lin, Minghui Tan
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Spastin, a microtubule-severing enzyme, is important for neurite outgrowth. However, the mechanisms underlying the post-transcriptional regulation of spastin during microtubule-related processes are largely unknown. We demonstrated that the spastin e
Externí odkaz:
https://doaj.org/article/223ba4e430064f96b57c1f61563bb219
Autor:
Jifeng Zhang, Yichen Yin, Zhisheng Ji, Zhenbin Cai, Bo Zhao, Jiong Li, Minghui Tan, Guoqing Guo
Publikováno v:
Neural Plasticity, Vol 2017 (2017)
Amyloid-β (Aβ) plays an important role in Alzheimer’s disease (AD), as oligomeric Aβ induces loss of postsynaptic AMPA receptors (AMPARs) leading to cognitive deficits. The loss of postsynaptic AMPARs is mediated through the clathrin-dependent e
Externí odkaz:
https://doaj.org/article/dc14bc7fb1c146d2bb50c733877693eb
Autor:
Yuhao, Yang, Jie, Yang, Yaozhong, Liang, Guowei, Zhang, Zhenbin, Cai, Yunlong, Zhang, Hongsheng, Lin, Minghui, Tan
Publikováno v:
Biochemical and Biophysical Research Communications. 643:77-87
Investigating novel mechanisms of neurite outgrowth via cytoskeleton is critical for developing therapeutic strategies against neural disorders. Rab3A is a vesicle-related protein distributed throughout the nervous system, but the detailed mechanism
Autor:
Shaojin Li, Luming Zhang, Haiyan Yin, Guowei Zhang, Minghui Tan, Zhenbin Cai, Tao Huang, Hongsheng Lin, Jun Lyu
Publikováno v:
Nursing in Critical Care.
Autor:
Shaojin Li, Yaozhong Liang, Jianyu Zou, Zhenbin Cai, Hua Yang, Jie Yang, Yunlong Zhang, Hongsheng Lin, Guowei Zhang, Minghui Tan
Publikováno v:
The Journal of biological chemistry. 298(9)
Katanin p60 ATPase-containing subunit A1 (KATNA1) is a microtubule-cleaving enzyme that regulates the development of neural protrusions through cytoskeletal rearrangements. However, the mechanism underlying the linkage of the small ubiquitin-like mod
Publikováno v:
Neuroscience. 434:83-92
Plexin family proteins mediate semaphorin signalling during dendritic arbour development. However, the role of PlexinA3 in the growth of dendrites of cultured cerebellar granule neurons (CGNs) is not known. We found that PlexinA3 colocalizes with CRM
Publikováno v:
Aging (Albany NY)
Hyperammonemia in the CNS induces irreversible damages to neurons due to ultimate cell loss. Neurite degeneration, a primary event that leads to neuronal cell death, remains less elucidated especially in hyperammonemia circumstances. Here, we found t