Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Zhen-Zhou Zhang"'
Autor:
Mi-Wen Zhang, Xue-Ting Li, Zhen-Zhou Zhang, Ying Liu, Jia-Wei Song, Xin-Ming Liu, Yi-Hang Chen, Ning Wang, Ying Guo, Li-Rong Liang, Jiu-Chang Zhong
Publikováno v:
Cell Stress Chaperones
Doxorubicin (DOX) is a chemotherapeutic drug for a variety of malignancies, while its application is restricted by the cardiovascular toxic effects characterized by oxidative stress. Ferroptosis is a novel iron-dependent regulated cell death driven b
Autor:
Xue-Ting Li, Jia-Wei Song, Zhen-Zhou Zhang, Mi-Wen Zhang, Li-Rong Liang, Ran Miao, Ying Liu, Yi-Hang Chen, Xiao-Yan Liu, Jiu-Chang Zhong
Publikováno v:
Free Radical Biology and Medicine. 193:459-473
Hypertension is one of the leading causes of chronic kidney disease characterized with renal fibrosis. This study aimed to investigate roles and mechanisms of sirtuin 7 (SIRT7) in hypertensive renal injury. Mini-pumps were implanted to male C57BL/6 m
Publikováno v:
Chinese Medical Journal. 135:1019-1026
Hypertension is the leading risk factor for global mortality and morbidity and those with hypertension are more likely to develop severe symptoms in cardiovascular and cerebrovascular system, which is closely related to abnormal renin-angiotensin sys
Autor:
Ying Liu, Zhao-Jie Dong, Jia-Wei Song, Li-Rong Liang, Lan-Lan Sun, Xiao-Yan Liu, Ran Miao, Ying-Le Xu, Xue-Ting Li, Mi-Wen Zhang, Zhen-Zhou Zhang, Jiu-Chang Zhong
Publikováno v:
Experimental cell research. 411(2)
Hypertensive renal injury is accompanied by tubular interstitial fibrosis leading to increased risk for renal failure. This study aimed to explore the influences of miR-122-5p in hypertension-mediated renal fibrosis and damage. 14-week-old male SHR a
Publikováno v:
European Journal of Pharmacology. 925:174977
Cardiovascular disorders and associated renal diseases account for the main cause of morbidity and mortality worldwide, necessitating the development of novel effective approaches for the prevention and treatment of cardiorenal diseases. Mammalian si
Autor:
Yu-Dan Cao, Ying Liu, Yuan Xu, Xiaoyan Liu, Ran Miao, Ying-Le Xu, Xiao-Fang Song, Mi-Wen Zhang, Jiu-Chang Zhong, Xue-Ting Li, Zhen-Zhou Zhang, Jia-Wei Song, Jing Li, Ying Dong
Publikováno v:
International Journal of Cardiology
Background Angiotensin converting enzyme 2 (ACE2) has recently been identified as the functional receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent response for novel coronavirus disease 2019 (COVID-19). Th
Autor:
Yu Liu, Ying Dong, Xinchun Yang, Qian Zhang, Ran Miao, Mei Yang, Zhen-Zhou Zhang, Jiuchang Zhong, Ying Liu, Xiaoyan Liu, Juan-Juan Song, Yi-Fan Fan, Jia-Wei Song
Publikováno v:
Journal of Molecular Histology
Apoptosis, inflammation, and fibrosis contribute to vascular remodeling and injury. Elabela (ELA) serves as a crucial regulator to maintain vascular function and has been implicated in the pathogenesis of hypertensive vascular remodeling. This study
Autor:
Xueyi Chen, Hai-Yan Jin, Jiu-Chang Zhong, Gavin Y. Oudit, Josef M. Penninger, Zhen-Zhou Zhang, Yu-Wen Cheng, Wang Wang, Ying-Le Xu, Bei Song
Publikováno v:
Hypertension. 70:1165-1175
The apelin pathway has emerged as a critical regulator of cardiovascular homeostasis and disease. However, the exact role of pyr1-apelin-13 in angiotensin (Ang) II–mediated heart disease remains unclear. We used apelin-deficient (APLN −/y ) and a
Autor:
Hai-Yan Jin, Yu-Wen Cheng, Zhen-Zhou Zhang, Ran Xu, Qian-Hui Shang, Qing Chang, Ying-Le Xu, Bei Song, Jiu-Chang Zhong, Lin-Xi Chen
Publikováno v:
Oncotarget
// Zhen-Zhou Zhang 1, 2, * , Yu-Wen Cheng 1, * , Hai-Yan Jin 1, 3, * , Qing Chang 1 , Qian-Hui Shang 4 , Ying-Le Xu 1 , Lin-Xi Chen 5 , Ran Xu 1 , Bei Song 1 and Jiu-Chang Zhong 1, 2 1 State Key Laboratory of Medical Genomics, Ruijin Hospital, Shangh
Autor:
Qing Chang, Hai-Yan Jin, Dingliang Zhu, Zhen-Zhou Zhang, Bei Song, Lai-Jiang Chen, Ran Xu, Jiu-Chang Zhong, Ying-Le Xu, Gavin Y. Oudit, Huimin Yu
Publikováno v:
Peptides. 79:49-57
Angiotensin-converting enzyme 2 (ACE2) has been shown to prevent atherosclerotic lesions and renal inflammation. However, little was elucidated upon the effects and mechanisms of ACE2 in atherosclerotic kidney fibrosis progression. Here, we examined