Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Zhen-Ye Zhang"'
Autor:
Shan-Shan Li, Lu Pan, Zhen-Ye Zhang, Meng-Dan Zhou, Xu-Fei Chen, Ling-Ling Qian, Min Dai, Juan Lu, Zhi-Ming Yu, Shipeng Dang, Ru-Xing Wang
Publikováno v:
Diabetes & Metabolism Journal, Vol 48, Iss 4, Pp 716-729 (2024)
Background Diabetes-induced cardiac fibrosis is one of the main mechanisms of diabetic cardiomyopathy. As a common histone methyltransferase, enhancer of zeste homolog 2 (EZH2) has been implicated in fibrosis progression in multiple organs. However,
Externí odkaz:
https://doaj.org/article/c1758dd2334043b98000374f55d1f0c9
Autor:
Lei Zhang, Huan-Huan Liu, Fan Yang, Zhi-Yuan Zhang, Zhen-Ye Zhang, Xiao-Xi Zhao, Ling-Ling Qian, Shi-Peng Dang, Ru-Xing Wang
Publikováno v:
Diabetology & Metabolic Syndrome, Vol 15, Iss 1, Pp 1-11 (2023)
Abstract Background Glucose fluctuations (GF) are a risk factor for cardiovascular complications associated with type 2 diabetes. However, there is a lack of adequate research on the effect of GF on myocardial fibrosis and the underlying mechanisms i
Externí odkaz:
https://doaj.org/article/60efd50d2dd84fca8d4377ce42a0dab7
Autor:
Lei Zhang, Huan-Huan Liu, Fan Yang, Zhi-Yuan Zhang, Ying Wu, Feng Li, Shi-Peng Dang, Zhen-Ye Zhang, Ling-Ling Qian, Ru-Xing Wang
Publikováno v:
BMC Cardiovascular Disorders, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background Diabetes is associated with myocardial fibrosis, while the underlying mechanisms remain elusive. The aim of this study is to investigate the underlying role of calcineurin/nuclear factor of activated T cell 3 (CaN/NFATc3) pathway
Externí odkaz:
https://doaj.org/article/fc4fd511b00849b8b1c6d04b85abef3c
Publikováno v:
Journal of Diabetes, Vol 15, Iss 5, Pp 368-381 (2023)
Abstract Background The relationship between glucose fluctuation and the risk of cardiovascular disease (CVD) in patients with diabetes remains elusive. Glycated hemoglobin (HbA1c) variability is a key parameter of glucose fluctuation. Methods PubMed
Externí odkaz:
https://doaj.org/article/3010a1c400234219bc6295975d4cf7df
Autor:
Feng Li, Tong-Yue Du, Li-Da Wu, Lei Zhang, Huan-Huan Liu, Zhen-Ye Zhang, Jie Zhang, Zhi-Yuan Zhang, Ling-Ling Qian, Ru-Xing Wang, Jian-Feng Hao
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Dilated cardiomyopathy (DCM) is characterized by the left ventricular dilatation and impaired myocardial systolic dysfunction with high mortality and morbidity. However, the underlying mechanisms remain elusive. We first identified the diffe
Externí odkaz:
https://doaj.org/article/c5439cefdc4b467d89b98a40b828cbca
Publikováno v:
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-12 (2021)
Abstract Co-expression network may contribute to better understanding molecular interaction patterns underlying cellular processes. To explore microRNAs (miRNAs) expression patterns correlated with AF, we performed weighted gene co-expression network
Externí odkaz:
https://doaj.org/article/08f0b70aca0e4bca839539b3f073b3f1
Autor:
Zhen-Ye Zhang, Shi-Peng Dang, Shan-Shan Li, Ying Liu, Miao-Miao Qi, Ning Wang, Ling-Feng Miao, Ying Wu, Xiao-Yan Li, Chun-Xin Wang, Ling-Ling Qian, Ru-Xing Wang
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundGlucose fluctuations may be associated with myocardial fibrosis. This study aimed to investigate the underlying mechanisms of glucose fluctuation-related myocardial fibrosis.MethodsStreptozotocin (STZ)-injected type 1 diabetic rats were ran
Externí odkaz:
https://doaj.org/article/d4cd23e1bd42474ba49436619d0015eb
Autor:
Feng Li, Tong‑Yue Du, Li‑Da Wu, Lei Zhang, Huan‑Huan Liu, Zhen‑Ye Zhang, Jie Zhang, Zhi‑Yuan Zhang, Ling‑Ling Qian, Ru‑Xing Wang, Jian‑Feng Hao
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/8ebf3ac825664863a57edd21e5df414a
Autor:
Feng Li, Lei Zhang, Li-Da Wu, Zhi-Yuan Zhang, Huan-Huan Liu, Zhen-Ye Zhang, Jie Zhang, Ling-Ling Qian, Ru-Xing Wang
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 15, p 4468 (2022)
Background: Age is an independent risk factor of the progress and prognosis of atrial fibrillation (AF). However, ablation outcomes between elderly and younger patients with AF remain elusive. Methods: Cochrane Library, Embase, PubMed, and Web of Sci
Externí odkaz:
https://doaj.org/article/5520f0511b2a444a9312ad0546cf2470
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Quercetin has attracted more attention in recent years due to its protective role against ischemia/reperfusion injury. Quercetin can alleviate oxidative stress injury through the inhibition of NADPH oxidase and xanthine oxidase, blockage of the Fento
Externí odkaz:
https://doaj.org/article/bf025fbdcef947bdae534d8462e38f36